Elias Copin

Thank you to @cp-devcell.bsky.social for selecting our story to feature on the cover of today’s issue of Developmental Cell!
Thank you to Zoë Ruiz for the wonderful art work! Read more here: www.cell.com/developmenta...

The Crick PhD program is open and there are amazing projects including our lab's. I couldn't recommend enough joining the program: brilliant community and excellent training and mentorship.
Specific project with us will be decided based on your interests.

Apply here www.crick.ac.uk/careers-stud...

Very sad news, John Gurdon has died.

A developmental biologist's developmental biologist, Nobel prize winner

His work is the foundation of much of today's dev & stem cell bio.

An inspiration to many, including me. Always asking questions & wanting the answers

www.magd.cam.ac.uk/news/profess...

Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Converging development: how cell paths unite in the embryo By tracking the fate of individual embryonic stem cells, researchers have found that endoderm cells – early embryonic cells that give rise to tissues such as the gut and lungs – originate from multipl...

Researchers have found that early embryonic cells start to specialise via converging developmental paths, rather than following linear trajectories as was previously believed.
www.crick.ac.uk/news/2025-09...

Check out @oliveringe.bsky.social's beautiful work on endoderm specification - super thankful to have been involved with this story!

Spatiotemporal orchestration of mitosis by cyclin-dependent kinase - Nature Experiments in fission yeast show that cyclin-dependent kinase is first activated in the nucleus, from which the mitotic signal is propagated from CDK at the centrosome to the cytoplasm.

Nature research paper: Spatiotemporal orchestration of mitosis by cyclin-dependent kinase

https://go.nature.com/444lRhe

If you are going to sunny California to the Salk Cell Cycle meeting don't miss @eliascopin.bsky.social's talk! Elias is our cell cycle and cell fate enthusiast and his presenting new exciting results. Come and say hi! I wish i was there too - it is going to be a fantastic meeting!!

Stem cells coaxed into most advanced amniotic sacs ever grown in the lab Nature - The sacs grew to roughly 2 centimeters wide and could be used to study early pregnancy.

The sacs grew to roughly 2 centimeters wide and could be used to study early pregnancy

https://go.nature.com/43jmUrY

New paper from @santoslab.bsky.social lab. Huge congrats to @borzogharibi.bsky.social & @oliveringe.bsky.social for this amazing work!

Registration and abstract submission for YEN 2025 is officially open!

We are looking forward to seeing you at the 17th Young Embryologist Network Conference on the 19th May 2025.

Attendence is FREE thanks to our amazing sponsors: @biologists.bsky.social @10xgenomics.bsky.social and Azenta.