Angel Felix - β’ΆπŸ΄ βš›οΈŽ's Avatar

Angel Felix - β’ΆπŸ΄ βš›οΈŽ

@italoromeno.bsky.social

β’Άβ˜­βš›οΈŽH Β«Know yourselves: be infertile and let the earth be silent after yeΒ» -- The Last Messiah, P. W. Zapffe -------------------------------------------------- #RRMS: #Tysabri, then #Tyruko, now #Ocrevus

189 Followers  |  220 Following  |  232 Posts  |  Joined: 08.09.2023
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Posts by Angel Felix - β’ΆπŸ΄ βš›οΈŽ (@italoromeno.bsky.social)

How To REDUCE HISTAMINE Inflammation in 12 Weeks
YouTube video by Dr. Paul Anderson How To REDUCE HISTAMINE Inflammation in 12 Weeks
21.02.2026 20:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Dr. Lawrence Afrin presents  β€œMast Cell Activation Syndrome”
YouTube video by EDS Awareness Dr. Lawrence Afrin presents β€œMast Cell Activation Syndrome”
02.11.2025 13:01 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
7 POWERFUL Ways to Reduce Histamine Inflammation Naturally
YouTube video by Dr. Paul Anderson 7 POWERFUL Ways to Reduce Histamine Inflammation Naturally

youtu.be/PQBAhfUw_kQ?...

27.10.2025 19:38 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Anti-allergic action of anti-malarial drug artesunate in experimental mast cell-mediated anaphylactic models - PubMed We report here for the first time that artesunate possesses anti-allergic activity by blocking IgE-induced mast cell degranulation, providing a foundation for developing artesunate for the treatment o...

pubmed.ncbi.nlm.nih.gov/23253152

17.10.2025 21:04 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Antibiotics Suppress Activation of Intestinal Mucosal Mast Cells and Reduce Dietary Lipid Absorption in Sprague-Dawley Rats The gut microbiota affects intestinal permeability and mucosal mast cells (MMCs) responses. Activation of MMCs has been associated with absorption of …

www.sciencedirect.com/science/arti...

15.10.2025 06:41 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The effect on brain atrophy of different MS disease modifying therapies based on a network meta-analysis (click the image) pubmed.ncbi.nlm.nih.gov/41080911/

14.10.2025 04:38 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
Pemafibrate and telmisartan combo may reverse fatty liver Explore the latest findings on fatty liver disease and how approved drugs may reduce liver fat accumulation and cardiovascular risks.

www.drugtargetreview.com/news/189185/...

14.10.2025 07:04 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Tried it already. Don't remember how it made me feel, but it's expensive

14.10.2025 07:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Dual role of histamine on microglia-induced neurodegeneration - PubMed Several hypotheses have been raised about the dual role of histamine in neurological disorders, and evidences have shown its crucial involvement in the modulation of microglia-mediated neuroinflammati...

pubmed.ncbi.nlm.nih.gov/28057587/

11.10.2025 01:11 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation - PubMed Overall, our results highlight the relevance of histamine in the modulation of microglial activity that ultimately may interfere with neuronal survival in the context of Parkinson's disease (PD) and, ...

Title says it all.
pubmed.ncbi.nlm.nih.gov/27260166/

11.10.2025 00:39 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Mast Cell Changes the Phenotype of Microglia via Histamine and ATP - PubMed Our results highlight the relevance of MC-derived histamine and ATP in the modulation of secretory and phagocytic activities that would explain the heterogeneity of microglial responses in different p...

pubmed.ncbi.nlm.nih.gov/33443845/

11.10.2025 00:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
The POTScast E178: Mast Cell Matters: Psychiatric Manifestations of MCAS with Dr  Janet Settle
YouTube video by Standing Up to POTS, Inc. The POTScast E178: Mast Cell Matters: Psychiatric Manifestations of MCAS with Dr Janet Settle

youtu.be/8NMvXD3JPJA?...

03.10.2025 09:15 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Clemastine and metformin extend the window of NMDA receptor surface expression in ageing oligodendrocyte precursor cells - Scientific Reports Scientific Reports - Clemastine and metformin extend the window of NMDA receptor surface expression in ageing oligodendrocyte precursor cells

www.nature.com/articles/s41...

29.09.2025 19:31 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Allergy, histamine 1 receptor blockers, and the risk of multiple sclerosis - PubMed These results do not support a strong link between allergic conditions and multiple sclerosis (MS) risk but suggest a possible beneficial effect of antihistamines on the onset of MS.

pubmed.ncbi.nlm.nih.gov/16505314/

18.09.2025 09:49 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Calming Down Mast Cells with Ketotifen: A Potential Strategy for Multiple Sclerosis Therapy? - PubMed Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) characterized by extensive inflammation, demyelination, axonal loss and gliosis. Evidence indicates that mas...

pubmed.ncbi.nlm.nih.gov/31463682/

18.09.2025 07:06 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Viewpoints Sigma-1 receptor agonist fluvoxamine for multiple sclerosis Accumulating evidence suggests that the Epstein-Barr virus (EBV) plays a key role in the development of multiple sclerosis (MS). Additionally, depressive symptoms often precede the onset of MS. Given ...

pmc.ncbi.nlm.nih.gov/articles/PMC...

15.08.2025 14:57 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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A Disease That Makes You Allergic to Meat And Dairy Is Spreading Around The World Hours after savoring that perfectly grilled steak on a beautiful summer evening, your body turns traitor, declaring war on the very meal you just enjoyed.
07.08.2025 18:04 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Long-Term Administration of Valacyclovir Reduces the Number of Epstein-Barr Virus (EBV)-Infected B Cells but Not the Number of EBV DNA Copies per B Cell in Healthy Volunteers Epstein-Barr virus (EBV) establishes a latent infection in B cells in the blood, and the latent EBV load in healthy individuals is generally stable over time, maintaining a β€œset point.” It is unknown ...

pmc.ncbi.nlm.nih.gov/articles/PMC...

26.07.2025 16:18 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
grey summer sky and its water mirror part to reveal pale glow surrounding far silhouette horizon and heron for a moment standing in ripples beyond framing branch and leaf of always marsh’s water’s edge

grey summer sky and its water mirror part to reveal pale glow surrounding far silhouette horizon and heron for a moment standing in ripples beyond framing branch and leaf of always marsh’s water’s edge

ways of heron silhouettes

20.07.2025 14:18 β€” πŸ‘ 3633    πŸ” 293    πŸ’¬ 68    πŸ“Œ 15
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Fosinoprilat alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-ΞΊB signaling in monocytes - PubMed The inhibitory effect of the fosinoprilat on the TRL4/NF-ΞΊB signaling pathway reveals a potential anti-inflammatory and anti-atherosclerosis target.

pubmed.ncbi.nlm.nih.gov/24036412/

16.07.2025 02:01 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Doxycycline increases neurogenesis and reduces microglia in the adult hippocampus Adult hippocampal neurogenesis results in the continuous formation of new neurons and is a process of brain plasticity involved in learning and memory. Although inducible-reversible transgenic mouse m...

pmc.ncbi.nlm.nih.gov/articles/PMC...

05.07.2025 12:55 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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<em>Clinical & Translational Immunology</em> | ASI Journal | Wiley Online Library This article proposes the novel hypothesis that bipolar disorder (BD) is a chronic autoimmune disease caused by Epstein–Barr virus (EBV) infection of autoreactive B cells, which accumulate in the bra....

onlinelibrary.wiley.com/doi/full/10....

03.07.2025 16:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Anti-EBV: Artificial intelligence driven predictive modeling for repurposing drugs as potential antivirals against Epstein-Barr virus - PubMed Epstein-Barr virus (EBV) is linked to various cancers like gastric carcinoma, nasopharyngeal carcinoma, and Burkitt's lymphoma, leading to around 200,000 deaths annually. Despite efforts, FDA-approved...

pubmed.ncbi.nlm.nih.gov/40458637/

02.07.2025 20:09 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Small Molecule Screening Identifies Inhibitors of the Epstein-Barr Virus Deubiquitinating Enzyme, BPLF1 Herpesviral deubiquitinating enzymes (DUBs) were discovered in 2005, are highly conserved across the family, and are proving to be increasingly important players in herpesviral infection. EBV’s DUB, B...

Small Molecule Screening Identifies Inhibitors of the Epstein-Barr Virus Deubiquitinating Enzyme, BPLF1 - PMC

28.06.2025 20:32 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Epstein–Barr virus pathogenesis and emerging control strategies - Nature Reviews Microbiology Sixty years after the discovery of the Epstein–Barr virus (EBV), MΓΌnz discusses new developments in the immunobiology of the first discovered human tumour virus, including vaccines and the role of EBV...

www.nature.com/articles/s41...

23.06.2025 21:56 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Beta-lapachone, a modulator of NAD metabolism, prevents health declines in aged mice - PubMed NADH-quinone oxidoreductase 1 (NQO1) modulates cellular NAD(+)/NADH ratio which has been associated with the aging and anti-aging mechanisms of calorie restriction (CR). Here, we demonstrate that the ...

pubmed.ncbi.nlm.nih.gov/23071729/

19.06.2025 11:35 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Ξ²-Lapachone suppresses neuroinflammation by modulating the expression of cytokines and matrix metalloproteinases in activated microglia - Journal of Neuroinflammation Background Ξ²-Lapachone (Ξ²-LAP) is a natural naphthoquinone compound isolated from the lapacho tree (Tabebuia sp.), and it has been used for treatment of rheumatoid arthritis, infection, and cancer. In...

jneuroinflammation.biomedcentral.com/articles/10....

19.06.2025 11:33 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Decreased ethanol preference and wheel running in Nurr1-deficient mice | Request PDF Request PDF | Decreased ethanol preference and wheel running in Nurr1-deficient mice | Nurr1 (Nr4a2) is a transcription factor expressed in dopamine cells from early development and throughout life. N...

www.researchgate.net/publication/...

13.06.2025 13:56 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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NURR1 Impairment in Multiple Sclerosis The transcription factor NURR1 is a constitutively active orphan receptor belonging to the steroid hormone receptor class NR4A. Although a genetic association between NURR1 and autoimmune inflammatory...

pmc.ncbi.nlm.nih.gov/articles/PMC...

12.06.2025 22:46 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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A potential protective role of the nuclear receptor-related factor 1 (Nurr1) in multiple sclerosis motor cortex: a neuropathological study - PubMed Cerebral cortical inflammation and neurodegeneration are hallmark pathological features of multiple sclerosis that contribute to irreversible neurological disability. While the reason for nerve cell d...

pubmed.ncbi.nlm.nih.gov/37056475/

12.06.2025 22:08 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0