Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours - Nature An understanding of the molecular mechanisms promoting the generation of immunoregulatory and tumour-promoting monocytes and macrophages is key to breaking the cycle of tumour myelopoiesis and develop...

🔬Our paper from the @miriammerad.bsky.social lab is now online! This is a story shaped over years of cross-disciplinary endeavor at @sinaiimmuno.bsky.social and labs across the world. 🧵:
www.nature.com/articles/s41...

Learning the cellular origins across cancers using single-cell chromatin landscapes - Nature Communications Understanding the cellular origins of cancers is crucial for improving diagnosis and treatment. Here, the authors utilize single cell chromatin accessibility data, patient whole-genome sequencing muta...

Alex's highly complementary study and fantastic story here: www.nature.com/articles/s41...

Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours - Nature An understanding of the molecular mechanisms promoting the generation of immunoregulatory and tumour-promoting monocytes and macrophages is key to breaking the cycle of tumour myelopoiesis and develop...

📝NEW STUDY📝 Cancer's first punch when battling the immune system may be rewiring myeloid progenitors in bone marrow so they become suppressive tumor macrophages blunting T-cell attacks. Find out how in @nature.com from @samhegde.bsky.social & @miriammerad.bsky.social 🧐 www.nature.com/articles/s41...

A targetable epigenetic node of myeloid progenitor dysregulation that sustains immunosuppressive lung tumor microenvironment, a target for improving immunotherapy outcomes @nature.com @miriammerad.bsky.social
@sinaiimmuno.bsky.social
www.nature.com/articles/s41...

YouTube video by Raging Moderates The Fallout from Charlie Kirk's Death

Jess and I share our thoughts on the assassination of Charlie Kirk.

@ragingmoderates.bsky.social
@jessicatarlov.bsky.social

youtu.be/Sz3SBK8PJik?...

Albeit not fully discovered yet, “how to get a second date”

admitting that you are not in control of who is joining your highly classified war plans chat is even more tragic…

We need more Jon Ossoffs in the Democratic Party.

This is just fantastic.

The worst lie of this lying twerp is that democrats are well organised

Measles in the 21st Century: Progress Toward Achieving and Sustaining Elimination Abstract. The global measles vaccination program has been extraordinarily successful in reducing measles-related disease and deaths worldwide. Eradication

Devastating to hear of a child's death from measles—a completely preventable disease. Even more concerning is public health officials downplaying the outbreak. attached here is an important article on the lifesaving impact of measles vaccines. #FollowTheData academic.oup.com/jid/article/...

Wait, are you telling me that microplastic-eating bacteria tablets are not available at the nearest drug store?!

Technical question…Is the permuted distribution computed across clones from all conditions? Very cool work!

Former NFL Kicker Arrested At City Council Meeting After Slamming 'Nazi' MAGA Movement Now that's resistance.

This is resistance.

New to bluesky, but I’m excited to share my work over the last few years with @jbuenrostro.bsky.social! Chronic inflammation creates an epigenetic memory in colonic stem cells, priming them for tumor growth: tinyurl.com/ColitisNagar.... Here’s a walkthrough of what we found (🧵)

This Is the Way to Stop Elon Musk Senate Democrats have the power to block federal contracts to Tesla and SpaceX. It’s the path to pushing Musk out of politics.

theintercept.com/2025/02/17/e...

This is the way.

Incompetence in Washington puts every American at risk, no matter how you voted. No one should be happy that the DOGE team - the same folks who randomly published classified U.S. security information online today - wants access to your bank account & Social Security numbers.

Cybertruck crash raises alarm bells about Tesla's self-driving software A crash involving a Tesla Cybertruck in self-driving mode this week has sparked worries about the reliability of the company's software that powers the feature, days after CEO Elon Musk said he would roll out a paid robotaxi service this year.

Unsafe at any speed www.reuters.com/business/aut...

NIH-supported research saves lives: here are two "poster" human beings to prove it.
Emily Whitehead: cured of her leukemia by CAR-T developed at Penn.
Victoria Gray: major symptoms of her sickle cell disease resolved following CRISPR gene editing - path paved at Boston Childrens, UW, UC Berkeley.

How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.

This is the most relevant article to NIH and research cuts I’ve seen.

Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !”

globalnews.ca/news/9793403...

Trump & Musk are making massive cuts to the National Institutes of Health.

I know there is a lot going on right now, but this is one of worst things they have done so far, will affect cancer research and trials, the search for cures, innovation and competitiveness, our universities. Your lives.

Well apparently nobody gives a shit about anything except eggs. So I’d say she’s hitting in the right direction

Rep. LaMonica McIver: "We are at war!"

Jasmine is on FIRE 🔥 🔥🔥

"...we are going to be in your face, we are going to be on your asses, and we are going to make sure you understand what democracy looks like...

...and this ain't it!"

I don’t see how showing that climate change it’s a 100+ years issue does you any favour in stressing the urgency of the issue..

YouTube video by FLAGRANT Mark Cuban on Running for Prez, Diddy Parties, & Destroying Big Pharma

This is me on the same podcast.

youtu.be/zWTHmqbbFOQ?...

Bishop Mariann Edgar Budde

Hero.

That’s who reminded me! 😂

So it’s either his bionic implants are short circuiting or he’s cleverly “disguising” a nazi salute for his AfD friends back in Germany.

Kudos to whoever did this one. Perfect.