Geanncarlo Lugo

Our new paper is out in @lsajournal.org
We explored how glycolysis inhibition in tuberculosis-infected macrophages can reduce HIV-1 spread.
🔗 Read it here: doi.org/10.26508/lsa...
Huge thanks to @Zoi Vahlas, @lucianabalboa.bsky.social, @oneyrolles.bsky.social & @chrisverollet.bsky.social

Our new paper is out in @lsajournal.org
We explored how glycolysis inhibition in tuberculosis-infected macrophages can reduce HIV-1 spread.
🔗 Read it here: doi.org/10.26508/lsa...
Huge thanks to @Zoi Vahlas, @lucianabalboa.bsky.social, @oneyrolles.bsky.social & @chrisverollet.bsky.social

A Harvard Scientist’s Tuberculosis Research Is Threatened by Trump’s Cuts Researchers who have lost funds warned of long-term repercussions, but several said their school should still refuse to comply with the federal government.

This feels straight out of a George Orwell novel: truly unbelievable. Targeting universities and their research on pandemic diseases is a self-defeating move, 1 that risks setting us back a century: Space Travel & Tuberculosis Research Are Hit by Trump’s Harvard Cuts www.nytimes.com/2025/04/16/u...

Mario Vargas Llosa: An Appreciation The Peruvian author Mario Vargas Llosa was the world’s savviest and most accomplished political novelist.

Una copa bien en alto por uno de mis autores favoritos. Gracias por las historias, las palabras, y la valentía. Buen viaje, Mario. 🥂📚
Farewell to the Last Writer of the Latin American Boom www.nytimes.com/2025/04/13/b...

🩸 New @naturecomms.bsky.social study with #IrsiCaixa collaboration explores therapeutic plasma exchange for #LongCovid, assessing its safety and efficacy in a phase II trial.

🧪 The study provides valuable insights into this complex condition.

👇🏽👇🏽👇🏽

www.nature.com/articles/s41...

Excited to share our last study. Huge congrats to Sarah Monard, Arnaud Métais, @gclugo.bsky.social, @chrisverollet.bsky.social and all colleagues!
We have found a mysterious cell type inside TB lung lesions that seems neuron-like but isn't quite a nerve cell.
Let's dive in👇

shorturl.at/x4Sb5

This new study shows that inhibition of S1pr3 ameliorates bleomycin-induced #PulmonaryFibrosis (PF) by reducing #macrophage M2 polarization via the PI3K/Akt-Stat3 signaling pathway, indicating that S1pr3 may be a potential target for PF treatment.

#OpenAccess: www.sciencedirect.com/science/arti...

cover of my new book everything is tuberculosis: the history and persistence of our deadliest infection

Everything Is Tuberculosis comes out THE DAY AFTER TOMORROW. I am so excited and also nervous. I hope you like it. Preorder your signed copy at everythingistb.com

@jakstat.bsky.social et al. of the Ardolino Lab show that PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway. rupress.org/jem/article/...

📘 In Tumor #Metabolism 2025: rupress.org/jem/collecti...
#KSTumorMetab25

Miao et al. highlight tRNA m1A modification as a regulatory checkpoint in cholesterol #metabolism in CD8+ T cells, suggesting potential novel strategies for #cancer #immunotherapy. rupress.org/jem/article/...

📘 In Tumor Metabolism 2025: rupress.org/jem/collecti...
#KSTumorMetab25

Revealed: NIH research grants still frozen despite lawsuits challenging Trump order The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.

"About a month after Donald Trump took office, almost all grant-review meetings remain suspended at the US National Institutes of Health, preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget." -Nature Press

go.nature.com/3EQlDjy

From Yemen to Mayotte, the spread of a highly drug-resistant cholera strain Scientists from the National Reference Center for Vibrios and Cholera at the Institut Pasteur, in collaboration with the Centre hospitalier de Mayotte, have revealed the spread of a highly drug-resist...

A recent study by the Institut Pasteur highlights the emergence of a cholera strain resistant to 10 antibiotics, including key treatments azithromycin and ciprofloxacin. This study demonstrates the need to strengthen global surveillance of the cholera agent. 🌍🔬 #cholera #AntibioticResistance

Join our Infectious diseases & antimicrobial resistance workshop !
Registration form : www.ipbs.fr/mira-worksho...
Programme and details : www.ipbs.fr/mira2025/

#AMR #WAAW #AntimicrobialResistance #PublicHealth #Antibiotics #Tuberculosis #healthcareinnovation

Opinion | I’m a health researcher. NIH’s pause on research grants could have a devastating cost. This is a potentially devastating event — not just for the scientific community, but for all Americans.

An explainer about how health research funding happens and why this NIH funding cycle shutdown matters: www.msnbc.com/opinion/msnb...

Are you affected by the Trump administration’s pause on health communications, science meetings, and reviews? Have you been affected by the Trump administration’s pause on communications, science meetings, and reviews? @statnews would like to hear from you.

Please repost! We’re trying hard to sort out rumors from truth + would like to hear from anyone affected by the new federal orders + NIH pause. Patients, scientists, health equity researchers: please contact us below. We won’t share anything without your permission. www.statnews.com/2025/01/25/t...

Sialylated IgG induces the transcription factor REST in alveolar macrophages to protect against lung inflammation and severe influenza disease Anti-inflammatory sialylated IgG is enriched in younger people and in mild influenza patients. Chakraborty, Yik-Ling Cheng, Edwards, Gonzalez, et al. define a mechanism by which sialylated IgG induces...

Adaptive immune regulation of innate immunity ✨ the paradigm has been innate immune regulation of adaptive immunity but the relationship is bidirectional. So much to discover and learn here.

www.cell.com/immunity/ful...

Thank you so much, Oli ! 🫶 Your words mean the world to me. Grateful to share this little blue planet with amazing people like you. Excited to connect, learn, and share together here! 🚀🌟

Hello, BlueSky! 🌟
Excited to join this community and start a fresh chapter here. Looking forward to connecting, sharing ideas, and building something meaningful together. Let’s make this space vibrant and inspiring!

Feel free to say hi or follow along. ✨
— Geanncarlo (@gclugo.bsky.social)

🎉 Congrats to Dr. Wendy Le Mouëllic on crushing her PhD defense! Another viva victory for the lab 🧪🎓 #PhDone

🎉Thrilled to announce the 10th anniversary of the
@ipbstoulouse.bsky.social Student Symposium in Toulouse, Nov. 4-5! Honored to welcome stellar keynote speakers Y. Belkaid, @mblokesch.bsky.social, F. Mechta-Grigoriou, and B. Küster - A celebration of science & discovery!
www.ipbs.fr/agenda/event...