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Jeff Chen

@jeffchenmycolab.bsky.social

Principal Research Scientist @VIDO.org & adjunct prof @usask.ca - focus on molecular microbiology, host-pathogen interxns, development of vaccines & drugs against human & bovine TB. - all views, opinions and comments my own.

498 Followers  |  194 Following  |  24 Posts  |  Joined: 05.11.2024  |  1.9629

Latest posts by jeffchenmycolab.bsky.social on Bluesky

Quote by Paul Sutter which says "The public needs to see scientists as poeple, rather than simply sources of information"

Quote by Paul Sutter which says "The public needs to see scientists as poeple, rather than simply sources of information"

Given the absolutely insane levels of disinformation and growing attacks on science and scientists, all scientists must be taught

- how to communicate effectively
- how to engage the public
- how to engage politicians and policy makers
- how to engage with the media
- how to counter misinformation

14.10.2025 01:17 โ€” ๐Ÿ‘ 96    ๐Ÿ” 25    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 4

Welcome, Shabaana!

06.10.2025 01:39 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Yes absolutely...we have a follow-up study demonstrating exactly that. Stay tuned

30.09.2025 22:45 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Thank you Steve ๐Ÿ™

30.09.2025 18:59 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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What a week! ๐ŸŽ‰From our Scientific Summit to the 50th Gala to celebrating our amazing team, thank you to everyone who joined us to mark 50 years of VIDO. The future of innovation, collaboration & impact starts now. #VIDOis50
@usask.ca

26.09.2025 16:51 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿšจ We're hiring for an animal technician! Apply now to join our team: vido.applytojobs.ca/veterinary%2...
#WorkAtVIDO #WorkWithUs #Hiring #JoinOurTeam #ResearchCareers

16.09.2025 18:54 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

In doing so, this talented young scientist discovered 1) a novel activator of ESX-1 gene transcription and 2) a novel vaccine that is as protective as BCG but does not compromise existing TB diagnostic tests.

12.09.2025 20:26 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Slim Zriba (PhD student) engineered Mycobacterium smegmatis to produce a functional Mtb ESX-1 system.

12.09.2025 20:26 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
Assembly of the Mycobacterium tuberculosis type VII ESX-1 secretion system in Mycobacterium smegmatis identifies a new transcriptional activator of esx-1 genes and a novel TB vaccine | Microbiology Sp... In this study, we modified Mycobacterium smegmatis, which is often used as a surrogate model organism in mycobacterial research, to produce and assemble a functional Mycobacterium tuberculosis (M. tb)...

Delighted to share our latest report in Microbiology Spectrum
journals.asm.org/doi/10.1128/...

12.09.2025 20:26 โ€” ๐Ÿ‘ 4    ๐Ÿ” 3    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0

๐Ÿ˜”

20.08.2025 06:54 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Seventy-year-old Parkinsonโ€™s drug shows promise against tuberculosis A medication developed in the 1950s to treat Parkinson’s disease may offer a powerful new tool in the fight against tuberculosis (TB), according to new research from the University of British Co...

Seventy-year-old Parkinsonโ€™s drug shows promise against tuberculosis | EurekAlert! www.eurekalert.org/news-release...

14.08.2025 18:09 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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My fantastic group threw me a surprise birthday lunch today ๐ŸŽ‰ ๐Ÿฅณ ๐Ÿช… Couldn't ask for a better group of people to be my partners in crime in the lab ๐Ÿ˜

31.05.2025 00:27 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Corporate administrators who have only experienced jobs whose main benefit was pay cannot fathom that the very best find intrinsic value in excellence and are best left to do it without undue interference or burden

24.05.2025 12:34 โ€” ๐Ÿ‘ 150    ๐Ÿ” 29    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3

Congratulations!

14.05.2025 02:44 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs.

Plant, Bacterial, Archaeal Non-model Bioeng
Custom Lab Hardware
Turn Key Genetic Design

Please repost for reach ๐Ÿ’š

02.05.2025 14:39 โ€” ๐Ÿ‘ 161    ๐Ÿ” 280    ๐Ÿ’ฌ 7    ๐Ÿ“Œ 4
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Join the Blokesch lab (@EPFL) as a postdoc in Molecular Microbiology ๐Ÿคฉ
Study Vibrio cholerae defense systems (phage/plasmid) in a dynamic, collaborative environment in Lausanne close to Lake Geneva in ๐Ÿ‡จ๐Ÿ‡ญ!
Please visit my lab's webpage for details about the position and how to formally apply.

25.04.2025 16:15 โ€” ๐Ÿ‘ 68    ๐Ÿ” 104    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3
NBC News: A deadly E. coli outbreak hit 15 states, but the FDA chose not to publicize it

NBC News: A deadly E. coli outbreak hit 15 states, but the FDA chose not to publicize it

Reuters: US FDA suspends food safety quality checks after staff cuts
April 17, 2025

Reuters: US FDA suspends food safety quality checks after staff cuts April 17, 2025

These stories landed today, within 11 hours of each other.

This presidential administration is a clear and present danger to the American people.

17.04.2025 20:29 โ€” ๐Ÿ‘ 11997    ๐Ÿ” 5302    ๐Ÿ’ฌ 285    ๐Ÿ“Œ 414

โ€œTuberculosis has long suffered a PR problemโ€ฆ We are looking at a world whereby, two years from now, 2 million people will die of #tuberculosis, instead of 1.25 millionโ€ฆ This is getting worse, not better, and I really hate it when we have the ability to make something better and we let it get worseโ€

12.04.2025 21:37 โ€” ๐Ÿ‘ 22    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿคฃ๐Ÿคฃ๐Ÿคฃ

10.04.2025 02:36 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
How researchers are trying to tackle Sask.'s high tuberculosis rates Saskatchewan's rate of tuberculosis infections was more than twice the national average in 2023. Scientists in the province hope to find a new drug treatment and a new vaccine. Jeffrey Chen, a princip...

To commemorate World TB day, got to discuss the state of TB in SK and our TB research at VIDO with Adam Hunter on CBC Radio
www.cbc.ca/player/play/...

24.03.2025 23:31 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Tuberculosis Resurgent as Trump Funding Cut Disrupts Treatment Globally The United States was the major funder of tuberculosis programs. Now hundreds of thousands of sick patients canโ€™t find tests or drugs, and risk spreading the disease.

The gutting of USAID has crippled tuberculosis programs, leaving hundreds of thousands of patients without tests or drugs and at risk of spreading the disease.

11.03.2025 17:06 โ€” ๐Ÿ‘ 214    ๐Ÿ” 101    ๐Ÿ’ฌ 17    ๐Ÿ“Œ 18

Amazing thesis work led by Sarah Danchuk now submitted for review and posted as preprint: ssrn.com/abstract=51598โ€ฆ. Short summary: M. bovis & M. orygis manifest enhanced virulence compared to M. tuberculosis in natural host model (calves) and small animal model (mice).

04.03.2025 23:56 โ€” ๐Ÿ‘ 6    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Iโ€™ll be in Pittsburgh at the Stand Up For Science March at Schenley Park. 11AM Friday March 7! Come on people! Support the good people who do research to improve and save lives!!

03.03.2025 01:23 โ€” ๐Ÿ‘ 17    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Europe PMCHome - Europe PMC Europe PMC is an archive of life sciences journal literature.

For all of you who cannot access pubmed, here is a good alternative:
europepmc.org

02.03.2025 09:56 โ€” ๐Ÿ‘ 226    ๐Ÿ” 85    ๐Ÿ’ฌ 8    ๐Ÿ“Œ 1
Europe PMCHome - Europe PMC Europe PMC is an archive of life sciences journal literature.

Remember, EuropePMC is actually better than #PubMed because it includes ALL preprints in search results, not just those including NIH-funded research.

europepmc.org

02.03.2025 08:28 โ€” ๐Ÿ‘ 484    ๐Ÿ” 178    ๐Ÿ’ฌ 12    ๐Ÿ“Œ 9
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To our American friends who may now be struggling to find health information on US websites: Please check out the Public Health Agency of Canada's website for helpful resources, updated dashboards & practical health tips.

๐Ÿ‡จ๐Ÿ‡ฆ๐Ÿ‡จ๐Ÿ‡ฆ๐Ÿ‡จ๐Ÿ‡ฆ

canada.ca/en/public-he...

01.02.2025 12:06 โ€” ๐Ÿ‘ 7571    ๐Ÿ” 3872    ๐Ÿ’ฌ 318    ๐Ÿ“Œ 307

And I can say with much satisfaction that the student has become much better at it than the teacher ๐Ÿ˜„

31.01.2025 20:11 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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VIDO held its annual research day - Slim Zriba (doctoral student) won 3rd prize for his project poster...super proud PI
Be on the lookout for some cool papers from this talented scientist๐Ÿ‘๐Ÿ‘๐Ÿ‘

31.01.2025 15:35 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Thanks for sharing Olivier

31.01.2025 15:28 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thank you Matthias...it's been a fun project

30.01.2025 19:04 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@jeffchenmycolab is following 20 prominent accounts