Silas Maniatis's Avatar

Silas Maniatis

@manimota.bsky.social

Father and scientist. Doing dad stuff in Brooklyn and science at New York Genome Center. ๐˜ˆ๐˜ด๐˜ด๐˜ฐ๐˜ค๐˜ช๐˜ข๐˜ต๐˜ฆ ๐˜‹๐˜ช๐˜ณ๐˜ฆ๐˜ค๐˜ต๐˜ฐ๐˜ณ, ๐˜š๐˜ฑ๐˜ข๐˜ต๐˜ช๐˜ข๐˜ญ ๐˜Ž๐˜ฆ๐˜ฏ๐˜ฐ๐˜ฎ๐˜ช๐˜ค๐˜ด ๐˜ˆ๐˜ณ๐˜ค๐˜ฉ๐˜ช๐˜ท๐˜ฆ ๐˜ฐ๐˜ง ๐˜ฎ๐˜บ ๐˜ต๐˜ช๐˜ฎ๐˜ฆ ๐˜ข๐˜ต ๐˜ต๐˜ฉ๐˜ฆ ๐˜ฐ๐˜ญ๐˜ฅ ๐˜ฑ๐˜ญ๐˜ข๐˜ค๐˜ฆ @๐˜ฎ๐˜ข๐˜ฏ๐˜ช๐˜ฎ๐˜ฐ๐˜ต๐˜ข๐˜ด๐˜ฐ๐˜ญ๐˜ฅ๐˜ด๐˜ต๐˜ถ๐˜ง๐˜ง.๐˜ฃ๐˜ด๐˜ฌ๐˜บ.๐˜ด๐˜ฐ๐˜ค๐˜ช๐˜ข๐˜ญ @๐˜ฎ๐˜ข๐˜ฏ๐˜ช๐˜ฎ๐˜ฐ๐˜ต๐˜ข ๐˜ฐ๐˜ฏ ๐˜ฎ๐˜ฐ๐˜ด๐˜ต ๐˜ฑ๐˜ญ๐˜ข๐˜ต๐˜ง๐˜ฐ๐˜ณ๐˜ฎ๐˜ด

1,682 Followers  |  4,194 Following  |  133 Posts  |  Joined: 16.09.2023  |  2.1052

Latest posts by manimota.bsky.social on Bluesky

That surprise being the proposal to eliminate all nuclear weaponsโ€ฆ To which Reagan said, nah, weโ€™re good. SDI (AKA Star Wars, space based defense against nuclear missiles) is more important.. What a tragedy for the world to have a demented old racist at the helm at a critical moment

11.10.2025 14:22 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Obviously the CDCโ€™s most important work is in protecting us from pathogens as part of normal life, but it is also a component of our national security, born of the Cold War. It astounds me that these โ€˜tough guysโ€™ talk so much ish but donโ€™t do the work to be ready. Big never been in a fight energy

11.10.2025 14:04 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

So whatโ€™s the plan if thereโ€™s a biological weapon used against the United States? We have no CDC as of last night, so we probably wouldnโ€™t even know until hospitals are so overwhelmed that thereโ€™s no way to deny it. Even then, weโ€™ll have no way to know if itโ€™s a weapon or to mount a defense.

11.10.2025 14:00 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Thread:

A year ago yesterday was a very happy day for me. I had lost my prostate. It was good riddance, as it was riddled with cancer. Iโ€™m now cancer-free โ€” and thankful for the tax-funded technology that saved my life.

10.10.2025 01:11 โ€” ๐Ÿ‘ 1654    ๐Ÿ” 247    ๐Ÿ’ฌ 29    ๐Ÿ“Œ 21

All of a sudden getting lots of inflammatory memeish divisive content pushed to my discover and popular with friends feeds here. Very reminiscent of 2016. Please be cognizant of what is being put in front of you

07.10.2025 01:42 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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90's NYC Nostolgia on Instagram: "Canal Street 90s Randomness 90s Canal Street, a carnival of everything and anything you could imagine for sale. Wires, pliers, clamps, duct tape, speakers, hundreds ... 747 likes, 37 comments - 90snycity on October 5, 2025: "Canal Street 90s Randomness 90s Canal Street, a carnival of everything and anything you could imagine for sale. Wires, pliers, clamps, duct tap...

www.instagram.com/90snycity/re...

05.10.2025 23:53 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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90's NYC Nostolgia on Instagram: "90s Canal Street Chaos . . . #90snostalgia #90sthrowback #GenX #NYC #TrashCulture #90sCanalStreet #StreetVendors #Electronics #90sCulture #NostalgiaTrip" Get an immersive experience of 90s Canal Street, with its eclectic mix of vendors, electronics, and NYC street culture. From the streets to the vendors, we're diving into the nostalgia and chaos of th...

Environs of NYGC when I moved to NYC. fun fact: those jnko and UFO โ€˜parachute pantsโ€™ started as a style in the NYC junglist scene after my buddy Alex โ€˜Lex Lugerโ€™ Dawson picked up a pair of surplus FRG paratrooper pants from the surplus store w the mortar in 1996

www.instagram.com/90snycity/re...

05.10.2025 23:50 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Massive immigration raid on Chicago apartment building leaves residents reeling: 'I feel defeated' The Department of Homeland Security said federal agents with Border Patrol, the FBI and the Bureau of Alcohol, Tobacco, Firearms and Explosives arrested 37 people in the raid.

Watson said she saw agents dragging residents, including kids, out of the building without any clothes on and into U-Haul vans. Kids were separated from their mothers, she said.
โ€œIt was heartbreaking to watch,โ€ said Watson, โ€œit was horrible.โ€

chicago.suntimes.com/immigration/...

02.10.2025 17:20 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
From the archives: Naturalist Jane Goodall
YouTube video by CBS Sunday Morning From the archives: Naturalist Jane Goodall

Thank you Dr Goodall for teaching us that non-humans can be sentient, that non-humans make tools, and that deep empathy with a being so different from oneโ€™s self is the path to wisdom. But most importantly, thank you for inspiring my daughter and for inspiring me. youtu.be/X-i9kV2Htuc?...

02.10.2025 02:21 โ€” ๐Ÿ‘ 7    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

NEWS: The federal govt is sending NYCโ€™s top disease control official to Arizona for a months-long stint at an Indian Health Service facility.

Thatย could complicate local infectious disease response efforts.

โ€œIf we have an outbreak, then weโ€™re fucked,โ€ a city health department staffer told me.

01.10.2025 20:23 โ€” ๐Ÿ‘ 71    ๐Ÿ” 31    ๐Ÿ’ฌ 6    ๐Ÿ“Œ 9
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National Defense Ministry Honors 11 Soldiers for Refusing Illegal Orders National Defense Ministry Honors 11 Soldiers for Refusing Illegal Orders Honored for rejecting illegal orders during martial law, Marine death probe

The South Korean Ministry of Defense has awarded medals of merit to 11 officers for disobeying direct orders of superiors during the martial law fiasco, orders that they deemed to be contrary to the constitution and endangerment to democracy.
www.chosun.com/english/nati...

27.09.2025 18:44 โ€” ๐Ÿ‘ 19684    ๐Ÿ” 6086    ๐Ÿ’ฌ 407    ๐Ÿ“Œ 836

Just a reminder that the plan always was to fire federal workers until every agencyโ€™s staffing is at the same level as during a shutdown. They put it in the original DOGE EO. So, please remind your representatives of this when they get worried about firings instead of furloughs.

25.09.2025 16:31 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
A color photograph of President Bill Clinton signing the Comprehensive Nucear-Test-Ban Treaty at a desk during a ceremony at the United Nations on September 24, 1996. A small UN flag is on the desk in the foreground.

A color photograph of President Bill Clinton signing the Comprehensive Nucear-Test-Ban Treaty at a desk during a ceremony at the United Nations on September 24, 1996. A small UN flag is on the desk in the foreground.

Today in 1996, the Comprehensive Nuclear-Test-Ban Treaty opened for signature at the United Nations. President Bill Clinton signed that day, as did representatives of 70 other states, including nuclear-weapon states China, France, the Russian Federation, and the United Kingdom.

24.09.2025 14:45 โ€” ๐Ÿ‘ 60    ๐Ÿ” 21    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1

www.uscis.gov/sites/defaul...

21.09.2025 01:24 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Fortunately (I guess) the govt just clarified/announced this is prospective onlyโ€ฆ for now? What are we even doing?

21.09.2025 01:24 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Thinking about and sending good will to all H1B holders abroad at meetings or visiting home etc, scrambling to make it back to the U.S. in the next 2hrs45min. This is unbelievably cruel and self destructive. H1B visa holders are the backbone of US dominance in science, engineering, & tech.

21.09.2025 01:15 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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TikTok misusing our personal data is bad.

Selling TikTok to a Trump-aligned billionaire family and one of his biggest political donors is even worse.

16.09.2025 21:26 โ€” ๐Ÿ‘ 2078    ๐Ÿ” 697    ๐Ÿ’ฌ 70    ๐Ÿ“Œ 30

What the hell? @npr.org is right now platforming Curtis Yarvin on its show โ€˜open to debateโ€™. The topic of debate: would the U.S. be better off as a dictatorship? This is insanely dangerous and stupid. We fought several wars, including our foundational war, that already answered this โ€˜questionโ€™

13.09.2025 22:14 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I mean, Iโ€™m merely a backwards American, for whom the renovated LaGuardia is the future, but how come you look like youโ€™re on a space 1999 spaceship version of CDG? Alsoโ€ฆ I hope the ERC can overlook certain.. things.. regarding the current state of affairs for US involved synergy proposals in Nov!

13.09.2025 05:50 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Yes. Of course. They requested 2 people with Hispanic last names come to the desk while boarding group A. TSA was already at the desk. No one came to the desk. By the end of group D, TSA had left the gate area

13.09.2025 03:38 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Iโ€™m returning from being on a panel at a conference in San Diego, and TSA is at the gate questioning everyone boarding the plane and checking IDs. Iโ€™ve never seen this before. They just questioned 4 active duty military personnel as they boarded

13.09.2025 03:23 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

As I fall asleep 24 years later, I know I will never again smell a structure fire without being instantly transported back to that day and the month of smoke that followed. Fuck all of these narcissistic performative little men. And I mean all of them. In every place & for any โ€˜causeโ€™ they claim.

12.09.2025 06:30 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Brooklyn golden hour remains undefeated

09.09.2025 22:41 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Boston is fired up and ready to get out the victory for @wutrain.bsky.social!

Vote in person tomorrow from 7am-8pm to send our incredible mayor back to City Hall.

08.09.2025 14:34 โ€” ๐Ÿ‘ 131    ๐Ÿ” 18    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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On this day in 1966, Star Trek first beamed into living rooms across America. None of us could have imagined then the journey it would set us on. And not just the cast and crew, but the millions of fans who would find hope, inspiration, and community in its vision of the future.

08.09.2025 18:34 โ€” ๐Ÿ‘ 13055    ๐Ÿ” 2442    ๐Ÿ’ฌ 599    ๐Ÿ“Œ 174
Joint Statement Calling for Secretary Kennedy Resignation The American Society for Microbiology released a joint statement calling for the resignation of HHS Secretary Robert F. Kennedy Jr.

As national medical, scientific, public health and patient organizations, we call for the resignation of HHS Secretary Robert F. Kennedy Jr. to ensure the health of the American people. Read our statement: asm.org/press-releas...

03.09.2025 23:10 โ€” ๐Ÿ‘ 735    ๐Ÿ” 341    ๐Ÿ’ฌ 12    ๐Ÿ“Œ 25

This was a wonderful project to work on! It also, in part, sparked a lot!

Beyond just our handles: @trackingskills.bsky.social aka trackingplumes (Bluesky and X), when I wanted to track mouse hands & Alex noses, we teamed up in 2017 to make @deeplabcut.bsky.social ๐Ÿ’œ

Delighted to see this out! ๐Ÿ™๐Ÿผ

02.09.2025 08:10 โ€” ๐Ÿ‘ 28    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Activation of polo-like kinase 1 correlates with selective motor neuron vulnerability in familial ALS Mutations in the Fused in Sarcoma (FUS) gene cause familial amyotrophic lateral sclerosis (ALS), characterized by selective degeneration of spinal motโ€ฆ

Always great to see nice work by good friends published! Congrats Olena, Hemali, and Neil!

www.sciencedirect.com/science/arti...

28.08.2025 22:22 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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A protein tunnel helps stressed lysosomes swell The endoplasmic reticulum donates lipids through a tunnel-like protein to help lysosomes expand

The endoplasmic reticulum donates lipids through a tunnel-like protein to help lysosomes expand.

Learn more in a new #SciencePerspective: https://scim.ag/45GWQrS

27.08.2025 13:07 โ€” ๐Ÿ‘ 51    ๐Ÿ” 14    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 3
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YO, what's up with all these almost-witchcraft techniques?? In this paper, they develop a way to freeze cells so quickly that it preserves Calcium waves midway!! WHAT??? HELLO??? So now you can do 3D reconstruction of calcium waves with just a normal confocal. www.nature.com/articles/s41...

26.08.2025 21:08 โ€” ๐Ÿ‘ 75    ๐Ÿ” 15    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3

@manimota is following 20 prominent accounts