Omega Lab

🧠 Join Our Team! 🧠
2 PhD candidates and 1 Study Nurse positions ope as part of our new RCT within the LeiCeM Excellence Cluster.
- PhD (deadline:15/10): tinyurl.com/35e5tbhy
- PhD within the IMPRIS-CONI (deadline:02/11): tinyurl.com/y9yt4akf
- Study Nurse (deadline:15/10): tinyurl.com/4zztjmj9

Only one more week until our hybrid Mini-Symposium on September, 2 2024 @mpicbs.bsky.social
with @neurometabolic.bsky.social @rachellippert.bsky.social, Leonie Koban & Mirjam Bloemendaal #WomenInStem You can still register here and join online or in person: survey.academiccloud.de/index.php/57...

Flyer showing title (Exploring the Gut-Brain Interplay), Date (September, 2nd 2024 from 9am - 11.30 am, CET), pictures of speakers & talk titles: Mirjam Bloemendaal (RadboudMC, Nijmegen, Netherlands): The gut microbiome & anti-depressant treatment response Sharmili Edwin Thanarajah (University Hospital Frankfurt, Germany): The impact of Western diet & peripheral metabolism on mental health Leonie Koban (Lyon Neuroscience Research Center, Lyon, France): Gut-brain interactions in human decision-making Rachel Lippert (German Institute of Nutrition Research, Potsdam, Germany): The role of maternal metabolic environment in lifelong alterations to offspring neurophysiology. Registration link: https://survey.academiccloud.de/index.php/578946?lang=en

We're super excited to announce our hybrid Mini-Symposium on September, 2 2024 (9-11.30 a.m. CET) @mpicbs.bsky.social covering
fascinating research on gut-brain interactions with
@neurometabolic.bsky.social @rachellippert.bsky.social Leonie Koban & Mirjam Bloemendaal. Please register & share!

Thanks to everyone involved: LIFE-Adult study center for data, #RHU_SHiVA #MPI_CBS for support and the #CBSOpenScience for open science spirit.
Find surrogate data+code at github.com/fBeyer89/VRF...

Our results underline that high blood pressure is the most important vascular risk factor to mitigate WMH progression and associated cognitive decline. WHR did not have additional negative association with WMH progression, even though previously reported.

A figure showing results from the linear mixed models, where WMH progression is significantly associated with global cognitive decline (p<0.001), with a Bayes Factor > 10

Stronger progression in WMH was related to stronger cognitive decline, globally ✅œ… but not for executive function ❌

A figure depicting the results of the linear mixed models, showing that change in DBP was significantly associated with WMH progression (p<0.001), with a Bayes Factor > 10

We found that baseline diastolic BP did not relate to WMH progression❌Œ, while change in DBP did ✅ œ…. Baseline WHR and its change was not related to WMH progression ❌Œ

We investigated modifiable risk factors of cerebral small vessel disease 🧠 and tested whether baseline and change in blood pressure 🩺 and waist-to-hip ratio 🍐Ÿ were associated with progression of white matter hyperintensities in older adults over seven years.

Progression of white matter hyperintensities is related to blood pressure increases and global cognitive decline – A registered report Abstract. White matter hyperintensities (WMH) reflect cerebral small vessel disease (cSVD), a major brain pathology contributing to cognitive decline and dementia. Vascular risk factors, including hig...

We are very happy to present our first registered report 🤩, now published in Imaging Neuroscience. After two very productive revisions of the stage 1 and stage 2 versions through @pci-regreports.bsky.social we can only recommend this!
** PAPER ** > doi.org/10.1162/imag...

Figures showing the effects of prebiotics on behavioral wanting ratings and decreases in brain activation in response to high-caloric, wanted food stimuli in prefrontal and brainstem areas.

New #RCT on the gut-brain axis 🧠🍏🦠 how #plant-based #prebiotics affect food decision-making now out in Gut 🥳
👏@omegalab.bsky.social

paper ➡️ doi.org/10.1136/gutj...
summary ➡️ t.co/XhJC1GlSwN
#neuroskyence #PsychSciSky #PsychSkySci #Medsky #neuroimaging #wisskomm #scicomm
#gut #brain #openscience

Three of our lab members, Daria EA Jensen (P.0748), Meghedi Vartanian (P.1065), and Konrad Endres (P.1111), have the opportunity to attend ECNP in Barcelona and present their posters today and tomorrow. Come & learn more about the hypothalamus, neuronal responses to visual food cues & ghrelin!