bioRxiv Developmental Biology

Apical spectrin organizes cortical actin filament bundles to pattern C. elegans cuticle ridges https://www.biorxiv.org/content/10.64898/2026.03.05.709908v1

A tunnel microtract organ for T cell progenitor homing is formed by neural crest morphogenesis via Sox10-Cdc42 axis https://www.biorxiv.org/content/10.64898/2026.03.05.709688v1

Distribution-Aware Federated Learning for Diabetes Prediction Using Tabular Clinical Data Under Non-IID and Class-Imbalanced Settings https://www.biorxiv.org/content/10.64898/2026.03.05.709751v1

Genome-wide discovery of cis-regulatory elements in a large genome https://www.biorxiv.org/content/10.64898/2026.03.07.709930v1

Postnatal Development of the Gray Short Tailed Opossum (Monodelphis domestica): Implications for Metatherian Decline at the K/Pg Boundary https://www.biorxiv.org/content/10.64898/2026.03.05.709990v1

Transcriptional feedback targeting Wnt pathway components reveals hidden heterogeneity in C. elegans seam cell lineages. https://www.biorxiv.org/content/10.64898/2026.03.04.709659v1

Cardiac-immune microniches programme macrophage states in the regenerating heart https://www.biorxiv.org/content/10.64898/2026.03.05.709830v1

Structure and genomic organization of the human DUX4 homologue bovine DUXC https://www.biorxiv.org/content/10.64898/2026.03.05.709741v1

ENS lineage potential is not intrinsically regionalized but is modulated by PTPRZ1 signaling https://www.biorxiv.org/content/10.64898/2026.03.05.709942v1

MEIOSIN retains an intrinsic STRA8-independent activity that drives meiotic entry across vertebrate evolution https://www.biorxiv.org/content/10.64898/2026.03.04.709545v1

A spatial and temporal atlas of tubulin isotype expression during neural crest EMT https://www.biorxiv.org/content/10.64898/2026.03.04.709627v1

Physiologic variation in sperm miRNAs tune embryonic gene regulatory programs and developmental outcomes https://www.biorxiv.org/content/10.64898/2026.03.04.709527v1

Temporal Gatekeeping Role of Lmx1 during chordate neural tube morphogenesis https://www.biorxiv.org/content/10.64898/2026.03.04.709676v1

Porcine extended pluripotent stem cell-derived somite-like mesoderm cells with Dox-driven PAX7 are robust seed cell resource for facilitating production of cultured meat https://www.biorxiv.org/content/10.64898/2026.03.03.709441v1

Measuring developmental information encoded by a dynamicallandscape https://www.biorxiv.org/content/10.64898/2026.03.03.709461v1

Short-chain PFAS exposure alters embryonic development and behavior in zebrafish https://www.biorxiv.org/content/10.64898/2026.03.03.709373v1

Fibronectin 1 is required for suture patency and dysregulated across craniosynostosis models in the mouse https://www.biorxiv.org/content/10.64898/2026.03.04.709647v1

Robust self-organization of livestock pluripotent stem cells into post-gastrulation embryo models with advanced neuronal and mesodermal structures https://www.biorxiv.org/content/10.64898/2026.03.02.709113v1

Topological Analysis of Multi-Network Threading in the Pancreas https://www.biorxiv.org/content/10.64898/2026.03.02.708973v1

Early life stress of maternal deprivation and peer-rearing jeopardize mesoprefrontal and mesolimbic dopamine receptors in the rhesus monkey https://www.biorxiv.org/content/10.64898/2026.02.28.708755v1

Macrophages regulate meiotic initiation and germ cell clearance in the developing ovary https://www.biorxiv.org/content/10.64898/2026.02.28.708733v1

Exploration of the screening and regulatory mechanisms of biomarkers related to ac4C modification in laryngeal squamous cell carcinoma patients based on single-cell analysis and machine learning https://www.biorxiv.org/content/10.64898/2026.02.28.708684v1

A Single-Cell Transcriptomic Atlas of Symmetry Breaking Across Eutherian Mammals https://www.biorxiv.org/content/10.64898/2026.02.27.708463v1

Sex specific systemic effects of sev-Gal4 driven activated Ras expression mediated through hnRNPs in Drosophila https://www.biorxiv.org/content/10.64898/2026.02.27.708457v1

Cone photoreceptor ablation in microglia-deficient larval zebrafish retina elicits a regenerative response alongside a compensatory immune cell response https://www.biorxiv.org/content/10.64898/2026.02.26.708140v1

Genome wide transcriptional changes underlie gradual and recurrent adaptation to protein malnutrition in zebrafish https://www.biorxiv.org/content/10.64898/2026.02.26.708142v1

Hypoxia-activated scleraxis a mediates epicardial progenitor differentiation into a unique cardiac perivascular cell type https://www.biorxiv.org/content/10.64898/2026.02.26.708296v1

A Mediator-dependent hypertranscriptional program governs neural stem cell fate decisions in vivo https://www.biorxiv.org/content/10.64898/2026.02.26.708183v1

Endocardial TIE1 synergizes with TIE2 to regulate the atrial internal muscular network assembly https://www.biorxiv.org/content/10.64898/2026.02.26.708190v1

Tissue composition shapes differential skeletal integration strategies during axolotl limb regeneration https://www.biorxiv.org/content/10.64898/2026.02.26.708175v1