Check it out all! 
Personalized Adaptive Cortical Electro-stimulation (PACE) for depression (osf.io/preprints/psyaโฆ) โฆ
โฆ.is now coming to Bipolar Disorder thanks to @BD2Discoveries !!! So happy to keep the work of moving forward in this capacity! Onward!!!
               
            
            
                29.10.2025 18:05 โ ๐ 7    ๐ 1    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            After the initial externalization testing where we confirm engagement of the individual networks by isolating behaviors, optimization and treatment include the entire symphony of networks. We think this is important to cover vast heterogeneity in TRD. We are testing spatial optimization too though.
               
            
            
                07.09.2025 23:36 โ ๐ 1    ๐ 0    ๐ฌ 1    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            super cool (& inspiring)! Finally read this and was wondering, for chronic stimulation (beyond initial 3-day electrode mappings), were all 4 electrode panels stimulated simultaneously? or were they isolated and that could vary with optimization? (didn't catch in paper, curious about PFC specificity)
               
            
            
                07.09.2025 22:30 โ ๐ 1    ๐ 1    ๐ฌ 1    ๐ 0                      
            
         
            
        
            
            
            
            
                                                 
                                                         
                                                
    
    
    
    
            Science of Learning symposium #flux2025 - sponsored by the Jacobs Foundation. First up: the LEVANTE research network which embraces open science principles to studying learning variability in children around the world. @fluxsociety.bsky.social
               
            
            
                04.09.2025 08:55 โ ๐ 11    ๐ 2    ๐ฌ 2    ๐ 0                      
            
         
            
        
            
            
            
            
                                                 
                                                
    
    
    
    
            Welcome to Dublin! From winding cobblestone lanes to literary pubs and centuries of innovation, Dublin blends rich history with vibrant culture. We canโt wait for you to experience it all during Flux 2025 โ excellent lineup of speakers, and our 2025 Pre-Conference Workshops, and more! #Flux2025
               
            
            
                03.09.2025 07:30 โ ๐ 5    ๐ 2    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            ๐๐พ๐๐พ๐๐พ
               
            
            
                03.09.2025 07:19 โ ๐ 4    ๐ 0    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            Hello all, see below! Letโs support Russell support our kids and @umn-midb.bsky.socialโฆtake a read! ๐๐พ๐๐พ
               
            
            
                03.09.2025 07:18 โ ๐ 1    ๐ 0    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            @drjuliamoser.bsky.social keeps killing it with these papers! Check this one out! ๐๐พ๐๐พ๐๐พ๐๐พ
               
            
            
                30.08.2025 20:59 โ ๐ 6    ๐ 0    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            FYI all. Anyone having issues with downloading our preprints I believe can still get to them when logged in. We also have some alternative links. Please reach out if you are having any issues.
               
            
            
                21.08.2025 15:38 โ ๐ 1    ๐ 0    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            ๐๐พ๐๐พ๐๐พ๐๐พ
               
            
            
                20.08.2025 12:23 โ ๐ 11    ๐ 3    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            A truly spectacular demonstration of the medical potential of precision mapping an individual patient's brain. I am so excited to be part of this work!
               
            
            
                13.08.2025 18:29 โ ๐ 10    ๐ 3    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            Quรฉ bien
               
            
            
                13.08.2025 16:34 โ ๐ 3    ๐ 2    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            From 20+ failed treatments to lasting remission. 
After decades with treatment-resistant depression and two near-fatal suicide attempts, โMikeโ found relief through Precision Functional Mapping and adaptive cortical stimulation developed at the University of Minnesota
               
            
            
                12.08.2025 20:54 โ ๐ 1    ๐ 1    ๐ฌ 1    ๐ 1                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            Treatment resistant depression is incredibly cruel. This is beautiful
               
            
            
                13.08.2025 03:43 โ ๐ 11    ๐ 4    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            He actually is and very articulate. He is teaching us a lot
               
            
            
                13.08.2025 14:54 โ ๐ 3    ๐ 1    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            Cool work here
               
            
            
                13.08.2025 11:35 โ ๐ 4    ๐ 2    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            Yes, please!
               
            
            
                12.08.2025 10:40 โ ๐ 1    ๐ 1    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            ๐๐พ๐๐พ๐๐พ๐๐พ
               
            
            
                12.08.2025 21:40 โ ๐ 2    ๐ 1    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            Oh do I understand. So full of happiness to see that Mike is doing better and has relief from the nightmare of treatment-resistant severe depression. Joy is bliss!
               
            
            
                12.08.2025 14:09 โ ๐ 8    ๐ 2    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            Congratulations! This is very important work.
               
            
            
                12.08.2025 08:44 โ ๐ 2    ๐ 1    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            ๐๐พ๐๐พ๐๐พ๐๐พ
               
            
            
                12.08.2025 10:38 โ ๐ 6    ๐ 1    ๐ฌ 1    ๐ 0                      
            
         
            
        
            
            
            
            
                                                 
                                                
    
    
    
    
            JOY ๐
               
            
            
                11.08.2025 22:46 โ ๐ 3    ๐ 2    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            ๐๐พ๐๐พ๐๐พ๐๐พ
               
            
            
                11.08.2025 20:31 โ ๐ 0    ๐ 0    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            electrodes can stay forever though like anything they can slowly degrade over time! We have some patients with electrodes in their brain for more than 20 years!
               
            
            
                11.08.2025 18:18 โ ๐ 4    ๐ 1    ๐ฌ 1    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            Wow, that is amazing! Iโd have a practical question: how long can the  electrodes stay inside?
               
            
            
                11.08.2025 14:56 โ ๐ 2    ๐ 1    ๐ฌ 2    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            Thanks you! Tagging @drdaviddarrow.bsky.social
               
            
            
                11.08.2025 18:05 โ ๐ 1    ๐ 0    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            Unreal work--proud to be part of the team @umn-midb.bsky.social !
               
            
            
                11.08.2025 17:50 โ ๐ 9    ๐ 2    ๐ฌ 0    ๐ 0                      
            
         
            
        
            
            
            
            
            
    
    
    
    
            This is fascinating
               
            
            
                11.08.2025 16:27 โ ๐ 6    ๐ 2    ๐ฌ 0    ๐ 0                      
            
         
            
        
    
         
        
            
        
                            
                    
                    
                                    
                            
                    
                    
                                            McLure II Professor 
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                                            I'm Nature's Deputy Editor for ecology, evolution and social science and handle papers in cog neuro, psych, and a variety of behavioral and social sciences. When I'm not working, I'm a mom (and sometimes even try to find time to play my harp or ski).
                                     
                            
                    
                    
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