Rakyan Lab

Paper in Nature 150 years ago. Beats reading any single-cell experiment…

Ha ha ha! 😂

Definitely worth watching!!

Franklin Stahl, biologist who helped reveal how DNA replicates, dies at 95 — The Washington Post An early experiment, with colleague Matthew Meselson, helped set the stage for a revolution in genetics.

apple.news/A6s0jhagcSLy...

Congrats!

Sandra, PhD student in our lab, is attending and loving everything about the course!

Our Evolutionary Biology and Ecology of Cancer Summer School #EBECancer2025 in full swing @eventswcs.bsky.social in sunny Hinxton, Cambridge. @florentmouliere.bsky.social giving a deep dive into tracking cancer evolution with cfDNA. @amyboddy.bsky.social @yosoykit.bsky.social @afrankell.bsky.social

Hello! Ever wonder what's "talking to" your favorite transcript, but were too scared to ask? In our review in @cp-cellreports.bsky.social, @mardakheh.bsky.social and I highlight new RNA-focused tools for discovering RNA interactions across organizational scales. Checkit!

tinyurl.com/ydn6e3ac

Excited to contribute to the Mitoribosome collaborative study led by @wredenberglab.bsky.social in @natcomms.nature.com🎉 "The mitochondrial methylation potential gates mitoribosome assembly"
The assembly starts before the completion of the rRNA gene cluster processing🧵
www.nature.com/articles/s41...

Rapid polygenic adaptation in a wild population of ash trees under a novel fungal epidemic Rapid evolution through small shifts in allele frequencies at thousands of loci is a long-standing neo-Darwinian prediction but is hard to characterize in the wild. European ash tree (Fraxinus excelsi...

Just out in Science: we demonstrate a micro-evolutionary shift in a single generation, involving thousands of genomic loci, giving younger ash trees more resistance to ash dieback, on average, than their parents
www.science.org/doi/10.1126/science.adp2990

Woah!

Excited to launch our AlphaGenome API goo.gle/3ZPUeFX along with the preprint goo.gle/45AkUyc describing and evaluating our latest DNA sequence model powering the API. Looking forward to seeing how scientists use it! @googledeepmind

I've wanted to write this article for years. About my and other's struggles to even survive sometime in #academia. Thank you to the amazing editors at @plosbiology.org that gave me the forum to write this piece. #science

Photograph of a stout wet black bug with dozens of tan-colored eggs on its back, some of them deflated after emergence. The bug is standing on a gray stone.

Happy Father's day as well to all the bug dads. Male water bugs, Belostomatidae, carry their partner's eggs around on their backs until they hatch, making sure the temperature and oxygen levels are acceptable, and the predators are at bay.

Fantastic study and preprint.

Wow!

🔎 Despite failed experiments as a student, alumnus Professor Azim Surani has spent his entire career trying to understand early mammalian development.

🔬 This year marks the 40th anniversary of his discovery of genomic imprinting — the process that tags specific genes, turning

It was such a great meeting. So proud to be part of this vibrant community. We keep going from strength to strength.

Cartoon showing a woman looking in to a microscope saying "Whoaah!!!" The caption states "The best part of Science is knowing, for a moment, something that nobody else in the world knows"

A reminder in these hard times. #sciencestrong

It was great to catch up with many friends and meet new people. Thank you all for participating in this event.

Thank you everyone for participating in the QMUL epigenetics centre launch event. It was a great success. Special thanks to SAB @deborahbourchis.bsky.social @lab-turner.bsky.social
Bas Heijmans and @elisaoricchio.bsky.social for interaction with our centre.

Check out our latest work‼️Fantastic study with really cool data and findings led by @allancarbal.bsky.social in collaborarion with Stephan’s lab. The one and many ways of getting a belly…

New from our lab @crick.ac.uk, in collaboration with the Enchev and Bukau labs.
By studying a protein that is difficult to fold, we discover fascinating new mechanisms by which the ribosome supports protein biogenesis.
www.biorxiv.org/content/10.1...

Very excited to share our latest work in #MolCell showing NPM1 stabilizing the association of nucleolus associated domains (NADs) and recruiting G9a to establish their repressive chromatin states. www.sciencedirect.com/science/arti...

Teeth first evolved as sensory tissue in the armored exoskeletons of ancient fish, fossil scans find Anyone who has ever squirmed through a dental cleaning can tell you how sensitive teeth can be. This sensitivity gives important feedback about temperature, pressure—and yes, pain—as we bite and chew ...

New paper from the lab: Our teeth arose as sensory organs on the outside of the body of ancient jawless fish.!! Congrats to Yara Haridy and the team!
Background and video: phys.org/news/2025-05...
Open Access Paper: www.nature.com/articles/s41...
News and Views: www.nature.com/articles/d41...

Join us for an in-person mini-symposium at @qmbci.bsky.social on July 16th to discuss several topics at the intersection of RNA biology and cancer. Free to come. Pizza and drinks to network @diunguyenvnuk.bsky.social @kevinrouault.bsky.social @rnasociety.bsky.social 👇👇

The sequel is more popular than the original!

A graph showing the price per pound for different vehicles and types of cheese. There are a surprising number of cheeses in the top half, such as Roquefort.

This is the best graph I've seen in a while 📊

The human pangenome continues to grow and improve! Release 2 is here! Click through for the details, but this is a pretty amazing dataset including not just the phased assemblies, but PacBio HiFi, ONT Ultralong, Dovetail/Illumina Hi-C, PacBio Kinnex, and Illumina WGS for all samples

www.wehi.edu.au/careers/make...
WEHI is looking for new lab heads! New and experienced lab heads welcome. Check out the ad, consider applying and share. We’re a collaborative bunch, in Australia, with fabulous technology, great colleagues at a values-driven organisation. @wehi-research.bsky.social