Brian Rifkin

a group of people are playing drums on a stage while a man holds a chair over his head . ALT: a group of people are playing drums on a stage while a man holds a chair over his head .

The Näirb is a three leg stool that comes in black and the original oak. Perfect for sitting at low tables to compose depressing poetry about environmental destruction.

ASIs Advance: NephJC Shorts on BaxHTN — NephJC A NephJC short on the latest baxdrostat trial

Another baxdrostat new/press release www.reuters.com/business/hea...

Not sure how different these findings are from this: www.nephjc.com/news/2025/9/... covered by @brianrifkin.bsky.social

Funniest nugget, AZ expects $5 billion sales 😂.

If that truly happens it will be a spiro-shame 😭

a cartoon character from the simpsons is holding a bottle of protein ALT: a cartoon character from the simpsons is holding a bottle of protein

Hmm, interesting take. I’m not sure we ever had good evidence that “low” protein diets were more than theoretically beneficial in CKD (I never recommended them). Having said that I’m all for #glipination and MORE protein!!

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Welcome to #TenPostNephJC
Last #NephJC we discussed tolerance induction in HLA matched 🫘 transplants with donor Hematopoietic stem cells (MDR-101).
Missed the Chimeri-chat? No worries - We’re quite “tolerant” to those who missed their IS(Informative Session)!

pubmed.ncbi.nlm.nih.gov/39922283/

Nobel Prize in Physiology or Medicine 2025 The Nobel Prize in Physiology or Medicine 2025 was awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

TREGs get the @nobelprize.bsky.social

www.nobelprize.org/prizes/medic...

Immune tolerance back in the news

#NephSky #Transplant

#NephJC 🥇

what he said✨✨✨

Immune tolerance in kidney transplantation: from first principles to clinical engineering — NephJC A commentary putting the chimerism and immune tolerance in perspective

Perhaps we can help! Great commentary by @nephroseeker.bsky.social

www.nephjc.com/news/2025/30...

See…we are cutting edge 🏆 #NephJC

www.nephjc.com/news/chimera...

The Nobel Prize in medicine goes to 3 scientists for work on peripheral immune tolerance Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi have won the Nobel Prize in medicine for their discoveries about peripheral immune tolerance.

BREAKING: Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi win the Nobel Prize in medicine for work on peripheral immune tolerance.

Diabetes Foundation of Mississippi | Ridgeland, MS Living life without limits is what the Diabetes Foundation of Mississippi (DFM) believes is possible for all those who have diabetes. Every dollar raised by the DFM stays in Mississippi to go toward e...

Hmm. It’s a Facebook link to a Facebook fundraiser. You can also give at the Diabetes Foundation of Mississippi (and DM so I can match it):

www.msdiabetes.org

This year marks 30 years as a type 1 diabetic.
I am raising money this month for backpacks with supplies for new diabetics ($300) & hypoglycemia boxes for schools ($100).
Goal is to raise $6K.
I will match $6K for a total of 30 🎒& 30📦
Thanks 😊

www.facebook.com/share/1771mmSvjH/?mibextid=wwXIfr

a woman in a very nice selection dress is standing in a room ALT: a woman in a very nice selection dress is standing in a room

Yes, no, yes. Wait a minute…YES!!!

a superhero holding a book with the words " justice is blind not heartless " ALT: a superhero holding a book with the words " justice is blind not heartless "

When did we even start caring about who appointed which judge?? Aren’t judges supposed to be impartial and passionlessly enforce the law?

donald trump is giving a speech and saying i know words on i have the best words . ALT: donald trump is giving a speech and saying i know words on i have the best words .

Sorry could resist 😜

a woman is wearing a knight costume and helmet . ALT: a woman is wearing a knight costume and helmet .

War ravaged????

a cartoon illustration of a message being sent from me to you . ALT: a cartoon illustration of a message being sent from me to you .

Sending good vibes and thoughts.
See you next week!

See I told you immune tolerance wasn’t the answer. Modifying antigens on donor kidneys makes much more sense (and won’t wear off).

Can a new class of drugs finally control hypertension in millions of patients? In this Q&A, Mineralys CEO Jon Congleton discusses how targeting aldosterone could reshape hypertension treatment. Aldosterone synthase inhibitors

interesting interview with Mineralys CEO (aka Lorundrostat maker) on @statnews.com
www.statnews.com/sponsor/2025...

I am not sure there is any role for this class beyond difficult PA given spiro and finerenone

ASIs Advance: NephJC Shorts on BaxHTN — NephJC A NephJC short on the latest baxdrostat trial

As we said, where do ASIs fit?

www.nephjc.com/news/2025/9/24/baxdrostat

Starrt AKI Va from Dominique Tomacruz

Strange papers

Cost-effectiveness analysis in @jama.com JNO

jamanetwork.com/journals/jam...
Seems to suggest standard (versus early) dialysis in AKI is more expensive? (It was still cost effective)
Which is strange considering in STARRTAKI there was *less* dialysis in standard

an older man with a surprised look on his face is talking about type 2 diabetes ALT: an older man with a surprised look on his face is talking about type 2 diabetes

May your fast be easy, and your shots painless 🕍

a black and white photo of soldiers with the words we are a part of the rhythm nation ALT: a black and white photo of soldiers with the words we are a part of the rhythm nation

I (don’t) got rhythm
I (don’t) got rhythm
I (don’t) got rhythm
Who could ask for anything more!

a group of knights sitting in a cave with the words that 's no ordinary rabbit on the bottom ALT: a group of knights sitting in a cave with the words that 's no ordinary rabbit on the bottom

Nope, it’s got huge fangs.

a man wearing a harley davidson shirt says this ALT: a man wearing a harley davidson shirt says this

This 💩 is 🍌 b-a-n-a-n-a-s (my theme song for the rest of this administration)