Intensive Care Medicine Experimental (ICMx)

How much #lung water is too much?🌊

This study demonstrates that CT-based estimates of EVLW in COVID-19 patients correlate well with TPTD values—suggesting a non-invasive, cost-effective alternative for #ICU monitoring.

🔗 doi.org/10.1186/s40635-025-00752-w
#MedSky

Can steroids reshape post-arrest metabolism?

High-dose methylprednisolone after OHCA alters plasma metabolites for 48 h—lowering ω-6 fatty acids and boosting tryptophan, arginine, and C3. A metabolic shift with therapeutic potential?

🔗 doi.org/10.1186/s40635-025-00754-8

#MedSky #CardioSky

In a new ICU mouse model, age and sex drive divergent responses to LPS-induced lung injury. Old males benefit most from ventilation, but old females fare worst. A step forward for translational critical care research.

🔗 doi.org/10.1186/s40635-025-00756-6

#MedSky #PulmSky #PulmCrit #IDSky

Mixed reality in the ICU? 👓

The ArtekMed system blends AR/VR for teleconsultation—rated promising by most users but still lags behind standard video calls in usability.

Real-time virtual care is coming…

🔗 doi.org/10.1186/s40635-025-00758-4

#MedSky

Can we control fever in acute brain injury without compromising brain oxygen? 🧠🌡️

Extended diclofenac infusions reduce temperature—but slightly lower PtO₂ too.

What does this mean for neurocritical care?

🔗 doi.org/10.1186/s40635-025-00759-3

#MedSky #NeuroSky

38th Annual Congress - Munich - ESICM The 38th Annual Congress, "LIVES," will take place in Munich from October 25-29, 2025, at the International Congress Centre Munich (ICM).

📢 Call for #Abstracts

#LIVES2025, the 38th Annual Congress of the @esicm.bsky.social , invites you to submit your original contributions in #IntensiveCare.

✨ Accepted abstracts will be published in a Supplement of #ICMx!

🗓️ Deadline: 10 April 2025, 23:59 CET

🔗

Awards - ESICM The ESICM Research Awards provide funding for innovative research projects in intensive care medicine across various disciplines.

🔬 The ESICM #Research Awards recognize groundbreaking projects that advance the field of #IntensiveCare.

🔹 Showcase your expertise
🔹 Gain recognition within the #ICU community
🔹 Contribute to the progress of #CriticalCare

📅 Deadline: 10 April, 23:59 CEST

www.esicm.org/research/awa...

#MedSky

📢 New Visual Abstract!

The effects of urine alkalinization on kidney function in critically ill patients with COVID-19: a proof-of-concept randomized clinical trial.

🔗 doi.org/10.1186/s40635-025-00739-7

#MedSky #ICMxVisualAbstract #FOAMcc #NephSky #Nephpearls

🩺 Exploring kidney protection in COVID-19

This trial assessed whether urine alkalinization could reduce #AKI risk.

👉 While pH targets were achieved, no significant clinical benefits emerged. A stepping stone for future research?

🔗 doi.org/10.1186/s40635-025-00739-7

#MedSky #NephSky #Nephpearls

📢 Mark your calendars for the #NEXTJamboree!

🎉 Join @esicm.bsky.social for the third edition of this free digital event, where young intensivists connect, share insights, and discuss the future of intensive care.

📅 April 29 – don’t miss it!

More details 👉 www.esicm.org/events/next-...

Capnodynamics vs. pulmonary catheterization 🏥

A new study finds that the capnodynamic method accurately estimates mixed venous oxygen saturation in post-op cardiac patients, offering a less invasive alternative to traditional monitoring.

🔗 doi.org/10.1186/s40635-025-00741-z

#MedSky #CardioSky

ICM Experimental | LinkedIn ICM Experimental | 65 followers on LinkedIn. 🚑 Intensive Care Medicine Experimental (ICMx) is an open-access journal dedicated to advancing experimental ICU research. As the official journal of the...

🔬 Stay up to date with the latest advances in intensive care medicine! At ICMx, we share groundbreaking research and key experimental studies. 🚑📚

Follow us not only here on Bluesky, but also on LinkedIn for more exclusive content!
🔗

Prehospital airway rescue: EVA vs. PCV

🩸 A hemorrhagic #trauma model shows that EVA via a 14F catheter provides sufficient oxygenation with lower intratracheal pressures and reduced lactate accumulation—could this be the future of field ventilation? 🌬️

🔗 doi.org/10.1186/s40635-025-00742-y

#MedSky

#AI Unlocks #ARDS Subphenotypes 🔬

New #MachineLearning models classify ARDS into "Efficient" & "Restrictive" subphenotypes—each with unique clinical outcomes. Could this shift the way we approach #ventilation?

🔗 doi.org/10.1186/s40635-025-00737-9

#MedSky #FOAMed #PulmSky #ICU #IntensiveCare

🤔 No One-Size-Fits-All for Mechanical Power in Ventilation: A new study explores how MP affects ventilator outcomes & highlights the need for personalized thresholds.

🗝️ Key takeaway? Median MP matters—universal cutoffs don’t.

🔗 doi.org/10.1186/s40635-025-00736-w

#MedSky #FOAMed #PulmSky #AI #ICU

🩸 Call for Submissions: Blood Purification in #Sepsis – From Bench to Bedside 🏥🔬

ICMx invites researchers to contribute to our new collection exploring the role of extracorporeal blood purification in sepsis.

🔗 Submit now: bit.ly/SubmitToICMx

#MedSky #NephSky #IDSky #IntensiveCare #CriticalCare

Intensive Care Medicine Experimental (ICMx) (@icmexperimental.bsky.social) An @esicm.bsky.social open access journal dedicated to translational research. 🔗 https://icm-experimental.springeropen.com/ ✍️ Authors http://bit.ly/AuthorsICMx 📲 Submit http://bit.ly/SubmitToICMx

📢 Stay connected with Intensive Care Medicine Experimental #ICMx on social media!

Follow us for the latest research & updates in #IntensiveCare. 🔬🩺

🔹 BlueSky: bsky.app/profile/icme...
🔹 LinkedIn: www.linkedin.com/company/icm-...

Join the conversation and be part of the ICMx community! 🚀 #MedSky

Intensive Care Medicine Experimental Intensive Care Medicine Experimental (ICMx) is a peer-reviewed open access journal  published under the SpringerOpen brand. It is dedicated to basic, ...

✨ Explore all our February 2025 reviews & stay ahead in #IntensiveCare!
🔗 icm-experimental.springeropen.com
#MedSky #FOAMed

🔹 Wearables in the #ICU 🏥📉
Can smart devices revolutionize ICU care? This review explores the potential & challenges of continuous, non-invasive patient monitoring.
Read here: 🔗 doi.org/10.1186/s40635-025-00738-8
#MedSky

Unlocking opportunities to transform patient care: an expert insight on limitations and opportunities in patient monitoring - Intensive Care Medicine Experimental Background Current patient monitoring technologies are crucial for delivering personalised and timely care and are critical in achieving the best health outcomes while maintaining high care…

🔹 Transforming patient monitoring 📡🔍
What are the biggest limitations—and opportunities—in ICU monitoring? Experts weigh in on the future of data-driven critical care.
Read the insights: 🔗 doi.org/10.1186/s40635-025-00733-z
#MedSky

🔹 AI vs. traditional models in #ARDS mortality prediction 🤖⚕️
Is AI better than logistic regression for predicting outcomes in ARDS? This systematic review & meta-analysis compares their performance.
Find out more: 🔗 doi.org/10.1186/s40635-024-00706-8
#MedSky #FOAMed #PulmSky #PulmCrit

🔹 Sepsis & the heart: A mitochondrial perspective 🦠❤️
Sepsis-induced cardiac dysfunction disrupts energy metabolism at the cellular level. This review dives into mitochondrial dysfunction & potential therapeutic targets.
Details: 🔗 doi.org/10.1186/s40635-025-00728-w #MedSky

🔹 Can we see acute illness? 👀📊
Facial cues may provide vital clues to patient deterioration. This scoping review explores how we can quantify them for early detection in critical care.
Read more: 🔗 doi.org/10.1186/s40635-025-00719-x #MedSky

🧵 February 2025 #Reviews in #ICMx!

Stay up to date with the latest in #CriticalCare & #IntensiveCare —from #AI in mortality prediction to the future of patient monitoring.

Don’t forget to like & share to keep the conversation going!

Check out our top reviews this month! ⬇️

#FOAMcc #Sepsis #ICU

Fighting macrolide-resistant pneumococcal #pneumonia 💊

A porcine model study shows that combining ceftriaxone, azithromycin & steroids enhances bacterial clearance & controls #inflammation. Could this be the optimal strategy?

Read more 🔗 doi.org/10.1186/s40635-025-00731-1

#MedSky #IDSky #PulmSky

Can wearables revolutionize #ICU monitoring?

📊 These devices offer continuous, non-invasive tracking of vitals, bridging gaps between intensive & step-down care. Challenges remain, but the future is promising!

Read more 👇
🔗 doi.org/10.1186/s40635-025-00738-8

#MedSky #FOAMed

Mitochondria & sepsis: a complex relationship? 🦠

🔬 New research in a porcine model shows how #sepsis severity drives renal mitochondrial dysfunction—offering insights into #AKI mechanisms beyond haemodynamic changes.

Read more: 👉 doi.org/10.1186/s40635-025-00732-0

#MedSky #NephSky #Nephpearls

📢 Calling all researchers! 📝✨ ICMx is now accepting submissions! Share your groundbreaking work in #IntensiveCare with a global audience. Open-access publishing & high visibility—submit today!

👉 https://icm-experimental.springeropen.com/

#MedSky #CriticalCare #ICMx

Transforming patient monitoring for better care! 🚑

Experts discuss how to overcome alarm fatigue, data overload & integration issues to optimize healthcare technology.

Future solutions await: 🔗 doi.org/10.1186/s40635-025-00733-z

#MedSky #FOAMed

🚀 NIV & Automation: A Better Match?

This study finds that IntelliSync+ improves synchronization, particularly with obstructive #lung mechanics & high leaks. Could this reshape #NIV delivery?

🔗 doi.org/10.1186/s40635-025-00726-y
#MedSky #PulmSky #PulmCrit