Scott Soderling

Congrats!!!

Congrats James! Loved hearing about this at an earlier CZI meeting!

I like o3 pro even better.

Steve Jobs was a vibe coder, he just prompted Steve Wozniak

Mini hearts, lungs and livers made in lab now grow their own blood vessels These sophisticated models will be used for human-development studies and drug testing.

Researchers are making ever more sophisticated mini organs in the lab — and now they can grow their own blood vessels

go.nature.com/4nNF3ri

A New Hub for Fighting Infectious Diseases with Smarter Models Duke University School of Medicine researchers will launch a new national Center of Excellence for Multiscale Immune Systems Modeling (MISM), funded by a U54 grant from the National Institutes of Heal...

The new Center of Excellence for Multiscale Immune Systems Modeling (MISM), launching soon by Duke University School of Medicine researchers, will transform how we understand and treat infectious and immune-related diseases.

#AcademicSky #MedSky

Congrats!!

Lab backpacking trip recently along the AT in NC. It's so nice to get away from it all, together.

Research funding cuts: What's at stake Researchers like Richard Huganir are closing in on a cure for SYNGAP1-related disorders. But in the face of federal funding cuts, can they finish what they started?

In this essay in Hopkins Magazine, I talk about how NIH budget cuts will delay or stop the translation of basic science to the clinic and impact kids with intellectual disability, autism, and epilepsy. hub.jhu.edu/magazine/202...

Duke University Sets New National Standard for Safe, Scalable AI in Health Care DURHAM, N.C. — Duke University School of Medicine researchers have developed two pioneering frameworks designed to evaluate the performance, safety, and reliability of large-language models in health ...

corporate.dukehealth.org/news/duke-un...

AI research in collaboration with cell biologists is transforming research at Duke. More discoveries coming soon!!

a group of people inside of a lab, huddled around a computer

The AI tool Raygun (named as an homage to “Honey, I Shrunk the Kids”) is just one of several tools that a team led by Duke's Rohit Singh, PhD, has built to help scientists work both faster and smarter.

🔗 Read more: medschool.duke.edu/stories/hone...

#DukeB&B #DukeCellBiology #AcademicSky #MedSky

Congrats to HHMI Freeman Hrabowski Scholars @channyskye.bsky.social , Josefina del Mármol (@delmarmollab.bsky.social), @yvetteefisher.bsky.social and Theanne Griffith (@doctheagrif.bsky.social), named 2025 McKnight Scholars for their demonstrated commitment to neuroscience & mentoring others! 🌟

Excited to be joining a fantastic community of neuroscientists!

a person in a lab coat sitting in a lab

Shuo Han, PhD, a Duke biochemist, is leading research to decode the gut microbiome’s chemical language. Her lab has released a free protocol that helps researchers detect over 800 gut-derived metabolites.

🔗 Read more: www.biochem.duke.edu/news/secret-...

#DukeBiochemistry #AcademicSky #MedSky

Looking forward to reading this.

In vivo multiplex imaging of dynamic neurochemical networks with designed far-red dopamine sensors Dopamine (DA) plays a crucial role in a variety of brain functions through intricate interactions with other neuromodulators and intracellular signaling pathways. However, studying these complex netwo...

Excited to share our Science paper on HaloDA1.0-the first genetically encoded far-red dopamine sensor! 🥳It enables powerful multiplex imaging in neurons, brain slices, and live animals.🧠🔬 #GRABsensors #Dopamine www.science.org/doi/10.1126/...

noaa map showing view line to PA

Fairbanks map showing view line into FL)

Aurora alert! It’s possible the aurora boralis may be visible tonight as far south as Alabama. Start looking tonight after dark around 10 pm

(I’ve attached both the NOAA and University of Alaska maps, the former is always very conservative with view lines)

www.swpc.noaa.gov/communities/...

Postdoc opportunity in the heart of Europe! Check out the flyer below.
Join our team on an international project with Anthony Holtmaat exploring synaptic plasticity and specificity in cortical and thalamocortical circuits.

Opinion | The U.S. Deported This Chinese Scientist, in a Decision That Changed World History

The unintended consequence of….. www.nytimes.com/2025/05/30/o...

What Is Academic Freedom? A letter from an alumnus

www.theatlantic.com/magazine/arc...

Congrats Joris!

Glad to see our new paper finally out! We show how the GPR158 receptor controls synapse maturation and function by silencing an intrinsic inhibitory mechanism.
authors.elsevier.com/a/1l7HS5Sx5g...
Work from Ben Verpoort and colleagues, with special thanks to our collaborators.

🧠 New in Nature from the fabulous Silver Lab @ Duke: A human-specific enhancer, HARE5, boosts radial glia proliferation, expanding neocortical size and connectivity. Knock-in mice showed enlarged cortices and more neurons. This highlights how regulatory DNA changes shaped human brain evolution.

Opinion | I Came to Study Aging. Now I’m Trapped in ICE Detention.

www.nytimes.com/2025/05/13/o...

Introducing KolossuS to address a 50-year old problem: which kinases are active in your pathway of interest?

As computational biologists, our work mostly involves post-hoc analysis algorithms. KolossuS is the rare case where a ML model enables entirely new capabilities. 1/

Yes, we have lots of exciting collaborative projects at the interface of computation and biology. Deep expertise in many domains between our labs, so a wonderful and committed training environment!

This was a wonderful collab with @scottsoderling.bsky.social , whose lab is situated next to ours.

If you want to do cool collaborative work like this, join us! We're building a great ecosystem of AIxBio at Duke.

Research at risk: Life-saving heart pumps for babies | Cornell Chronicle After receiving a stop-work order from the federal government, the future of a device to help children with heart defects is uncertain.

One of grants frozen at Cornell: $6.7M (4 yrs) to develop heart pumps for babies born w/ heart defects.

It took decades of work to get to point of prepping device for in-human clinical trials. No private company could do this.

The cruelty of the Trump administration is heartbreaking. So to speak.

Just snagged some tickets for the upcoming Pearl Jam concert in Raleigh NC. SO EXCITED!