@timead.bsky.social
Research shows up to 45% of Alzheimer’s cases may be preventable. TIME-AD compares data across studies to fill key research gaps, with support from the National Institute on Aging (NIA). Learn more: www.time-ad.org
It’s Mental Illness Awareness Week 🧠
This year’s theme, Building Connection, highlights the power of meaningful connections for mental health. At TIME-AD, we study how depression, treatment, and social isolation shape dementia risk.
Read about it here: www.time-ad.org/projects
📊 In TIME-AD’s latest publication, researchers combined test scores across two cohorts reflecting a range of backgrounds to understand drivers of differences in cognitive aging.
🧠 Read the article here: tinyurl.com/43ss93ry
#EpiSky #NeuroSky
Today, on #InternationalDayOfOlderPersons, we celebrate the important role that older adults play in our families, communities, and societies.
At TIME-AD, we’re striving for a dementia-free future by studying how to reduce risks and support healthy brain aging 🌍
Did you know❓
There are estimated to be over 55 million people worldwide living with #dementia.
TIME-AD examines various interventions that could help reduce the risk of developing Alzheimer’s disease and related dementias.
Learn about our work: www.time-ad.org
@alzint.org
🌟 Scientist Spotlight: Yulin Yang, Postdoctoral Researcher, UCSF
Yulin explores how social isolation can contribute to and result from pain and Alzheimer’s disease–related dementias (ADRDs).
🔗 Learn more: www.time-ad.org/yulin-yang
#ScientistSpotlight #TIME-AD
🔁 ICYMI: In a recent #TIMEAD publication, we share methods to compare findings from dementia studies that use different cognitive tests. This helps researchers to better compare the impact of interventions.
📄 Read the full article: pubmed.ncbi.nlm.nih.gov/40000573/
#ADRD
Yesterday #WorldAlzheimersDay 🧠
57M people live with #ADRD worldwide. Research points to ways to prevent up to 45% of cases.
TIME-AD is advancing knowledge and bringing together data to reduce this burden.
Social and clinical factors shape dementia and care experiences. Silvia Miramontes, TIME-AD investigator, studies patient data to spot and close gaps in care.
🔗 Learn more about her research and motivations: www.time-ad.org/silvia-miram...
#TIME-AD #ResearchReflections
September is #HealthyAgingMonth and #DeafAwarenessMonth 🩺
Read about what TIME-AD is doing to understand the link between hearing loss and dementia: www.time-ad.org/projects/sus...
TIME-AD turns 1! 🎉
Over the past year, we’ve combined diverse data and innovative methods to explore ways to prevent dementia.
🌐 Learn more: www.time-ad.org
#TIMEAD #ADRD
🔎 Meta-analysis and triangulation depend on credible science.
📈 TIME-AD’s latest paper, led by Dr. Sarah Ackley, examines 20,000+ abstracts using an LLM to determine whether P value trends reflect changes in p-hacking, publication bias, or statistical power.
Read it: tinyurl.com/3f3nuxma
Social isolation is linked to poor mental health and higher risk of dementia in older adults. TIME-AD investigators like Mary are studying how to intervene with meaningful social connection.
🔗 Read more: www.time-ad.org/mary-thoma
#TIME-AD #ResearchReflections
🔁 ICYMI: TIME-AD introduces the AI-Y Checklist, a framework for evaluating the development and deployment of AI tools in population health through an ethical lens.
🔗 Check it out: link.springer.com/article/10.1...
🚨 New from TIME-AD: Researchers developed measure to capture social isolation in the Health & Retirement Study. It works for all participants and will help show how isolation contributes to Alzheimer’s & dementia.
📖 Read it in JAGS: agsjournals.onlinelibrary.wiley.com/doi/10.1111/...
🔁 ICYMI: TIME-AD published an article in the American Journal of Epidemiology on “The Association of Alzheimer's Disease Genetic Risk with Social Connectedness in Middle- And Older-Ages”
Read it here: pubmed.ncbi.nlm.nih.gov/40512627/
🌍 September is #WorldAlzheimersMonth
🧠 #TIME-AD is advancing research on modifiable risk factors that could inform interventions with the goal of healthy brain aging.
🔗 www.time-ad.org
#AskAboutDementia #AskAboutAlzheimers
🔁 ICYMI from TIME-AD!
How much time and follow-up is needed to study cognitive decline over time?
🔗 Our article in the American Journal of Epidemiology breaks it down: academic.oup.com/aje/advance-article/doi/10.1093/aje/kwaf049/8071273
#TIME-AD #EpiSky #NeuroSky
⚙️Check out the software we developed to accompany TIME-AD’s recent publication on methods to crosswalk between cognitive test scores.
It is under development and feedback is welcome!
🔗 Download & instructions: jrgant.github.io/cogxwalkr/
📊 Differences in cognitive tests make it hard to compare results across studies.
This new #TIME-AD article offers methods to align effect estimates to increase comparability across studies and trials.
🔗 pubmed.ncbi.nlm.nih.gov/40000573/
🔁 ICYMI at #AAIC25:
TIME-AD presented new research on whether removing amyloid from the brain can accurately predict declines in cognition and functioning.
📖 Read the preprint to learn more: www.medrxiv.org/content/10.1...
#TIMEAD #EpiSky
🌟 Scientist Spotlight: Silvia Miramontes, PhD Candidate, UCSF
Silvia’s research explores how clinical and social factors shape the trajectory of dementia
Outside the lab, you might find Silvia on a scenic run, a long walk, or at a city viewpoint.
🔗 Learn more: www.silviamiramontes.com
💡New from TIME-AD!
In our latest journal article, we introduce and apply a checklist for making sure AI is used responsibly across global health and research settings.
📊Check it out in Current Epidemiology Reports: link.springer.com/article/10.1...
#TIME-AD #ResponsibleAI
#ΨMCA2025 has come to an end!
We’re heading home energized after a week full of discussion around cognitive aging research 💬
Thank you to the organizers and all who joined us!
#TIME-AD #DementiaResearch
Such a great scene at #ΨMCA2025 as usual. This year's workshop focuses on issues central to evidence triangulation, including synthetic data, cross-walking between measures used in different studies, and formalizing the research infrastructure (samples) needed to fulfill #NAPA and #EndAlz
14.08.2025 21:19 — 👍 3 🔁 1 💬 0 📌 0
Halfway through #ΨMCA2025 🧠
📸Jingxuan Wang, Postdoctoral Associate at BU, presented TIME-AD research on “Methods to Crosswalk Between Cognitive Test Scores.”
Full article: pubmed.ncbi.nlm.nih.gov/40000573/
We’ve arrived at #ΨMCA2025!
Excited for a week of stats, science, and conversations around measuring cognitive aging.
🔗 psymca.org
#TIME-AD
🌟Scientist Spotlight: Mary Thoma, PhD Candidate, UCSF
Mary studies how social isolation affects dementia, and explores interventions like volunteering.
🔗Learn more: epibiostat.ucsf.edu/content/mary...
#ScientistSpotlight #TIME-AD
📍Next week, TIME-AD is heading to the 2025 Psychometric Methods for Cognitive Aging (ΨMCA) Conference!
We’re excited to connect with researchers on new ways to measure and understand memory, thinking, and brain health as we age.
🔗 psymca.org
#TIME-AD #ΨMCA2025
New research from #TIME-AD 🚨
Can #Alzheimer’s genetic risk affect how socially connected we feel as we age?
💡 Our latest study looks at the link between genetic risk and social connectedness in mid & later life.
Read it in the American Journal of Epidemiology: tinyurl.com/3x8py35d
That’s a wrap on #AAIC25! 🤝
Thanks to everyone who joined TIME-AD’s sessions and shared ideas to keep dementia research moving forward.
Grateful to the @alzassociation.bsky.social for putting on a productive conference.
#TIME-AD #EndAlz #NeuroSky
