Triangulation of Innovative Methods to End Alzheimer’s Disease

Just discovering TIME-AD? Welcome!

We’re an NIA-funded initiative focused on identifying what works to prevent and delay dementia by comparing results across study designs and populations.

Follow along for research updates and insights.

🌐 www.time-ad.org

Harnessing Geospatial Artificial Intelligence (GeoAI) for Environmental Epidemiology: A Narrative Review - PubMed There have been two major recent shifts in geospatial data types and analytic methods. First, novel methods for statistical prediction, combining geospatial analysis with machine learning and artificial intelligence (GeoAI), allow for scalable geospatial exposure assessment within large population h …

🔁 ICYMI: “Harnessing Geospatial Artificial Intelligence (GeoAI) for Environmental Epidemiology: A Narrative Review”

This paper provides an overview of recent advances in machine learning and artificial intelligence for environmental epidemiology research.

🔗 pubmed.ncbi.nlm.nih.gov/41003951/

The cost of care for ADRD is significant. According to the @alzassociation.bsky.social, unpaid caregivers in the US provided over 19 billion hours of care in 2024.

Dementia research supports not only those with the disease, but the caregivers who support them.

#caregiver #Alzheimers #dementia

February marks Black History Month, a time to recognize the contributions and lasting impact of Black individuals and communities.

At TIME-AD, this reflection reinforces our commitment to rigorous research that strengthens impact for all populations.

#BlackHistoryMonth #BHM

New TIME-AD study! 🚨

Using causal inference “transport” methods, researchers show how findings from well-characterized Alzheimer’s clinical samples (ADNI) can be applied to real-world populations (ARIC-PET), improving dementia research generalizability.

🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...

NACC data: Who is represented over time and across centers, and implications for generalizability INTRODUCTION Since 2005, the Alzheimer's Disease Research Centers (ADRCs) have recruited participants into the Uniform Data Set (UDS), but enrollment trends and center-level differences remain under...

🔁 ICYMI: TIME‑AD’s latest study examines 20 years of NACC UDS data, showing how participant recruitment has changed across Alzheimer’s Disease Research Centers and what it means for generalizing findings.

🔗 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

🔬 L. Paloma Rojas Saunero, MD, PhD

Paloma is a TIME-AD researcher using causal inference to ask clearer questions with real-world data- reducing bias and linking results to real interventions.

🔗 Read more about her research: www.time-ad.org/paloma-rojas...

#TIMEAD #ResearchReflections

According to the @alzassociation.bsky.social, nearly 12 million Americans provide unpaid care for people with dementia. 🧠

We’re grateful to caregivers and families who share their lived experiences to strengthen research and move us toward a dementia-free future.

#DementiaCare #DementiaCaregiver

Today is Martin Luther King Jr. Day ⚖️

On this day of service, we are inspired to continue working toward a future where everyone has the opportunity to live a healthy, fulfilling life.

Let’s carry forward Dr. King’s legacy of service, empathy, and action.

#MLKDay #MLKDay2026

🔁 ICYMI: TIME-AD’s recent article published in AJE explores the individual and joint impacts of social adversities on cognitive health.

📖 Check it out: academic.oup.com/aje/advance-...

🌟 Scientist Spotlight: Ryo Ikesu, Postdoctoral Scholar, UCLA

Ryo examines how hypothetical interventions to reduce loneliness might affect memory function among middle-aged and older adults.

🔗 Learn more: www.time-ad.org/ryo-ikesu

#ScientistSpotlight #TIME-AD

Earlier this year, TIME-AD’s Dr. Yulin Hswen co-authored a narrative review on #GeoAI in environmental epidemiology. The findings show how GeoAI, smartphones, and wearables enable scalable, high-resolution exposure assessment. 🗺️⌚

Read it here: pubmed.ncbi.nlm.nih.gov/41003951/

#EpiSky

Two days left to apply for the Spring TIME-AD Fellowship!

Don’t miss your chance to join impactful AD/ADRD research.

📅 Deadline: Jan 11, 11:59 PM
🔗 Application: tinyurl.com/5n7yxx7n

🔬 Reminder: UCSF is reviewing applications for a Postdoc to support the TIME-AD Analytics Core.

The position will apply advanced causal inference and data fusion methods to questions in cognitive aging research.

Learn how to apply: www.time-ad.org/postdoc-rese...

#Hiring #Academia

There’s one week left to apply for the Spring TIME-AD Fellowship!

BU master’s students can join faculty-led AD/ADRD research.

📅 Deadline: Jan 11, 11:59 PM
💰 $1,000 stipend

Learn more and apply today: www.time-ad.org/fellowship

Happy New Year! ✨

We’re entering 2026 grateful for the TIME-AD community and excited for another year of innovative research and methods that bring us closer to preventing dementia.

What are you looking forward to this year? 💬

#HappyNewYear #2026

As the new year approaches, we’re reflecting on a year of innovation, collaboration, and evidence triangulation for dementia prevention.

None of this would be possible without our incredible TIME-AD investigators and early career scientists.

🌟 Meet a few of them: www.time-ad.org/scientist-sp...

On break with some extra time on your hands? We’ve got you covered!

📚 Have a look through TIME-AD’s publications, advancing understanding of dementia through evidence triangulation: www.time-ad.org/publications

📢 Postdoctoral Research Opportunity in Biostatistics at UCSF

Come work with the TIME-AD Analytics Core on causal inference & information synthesis with applications in cognitive aging research.

🔗 Full details and application instructions: www.time-ad.org/postdoc-rese...

#Hiring #Academia

🌟Scientist Spotlight: L. Paloma Rojas Saunero, Postdoctoral Scholar, UCLA

At TIME-AD, Paloma develops methods to study Alzheimer’s outcomes and supports real-world studies that mirror pragmatic trials.

🔗Learn more: www.time-ad.org/paloma-rojas...

#ScientistSpotlight #TIME-AD

Happy holidays from TIME-AD! 🌟

Wishing you a peaceful, happy, and healthy holiday season. Thank you for being part of our community as we continue our work to advance dementia research and bridge knowledge across studies and populations 💛

🚨 New publication co-authored by TIME‑AD’s Fan Xia!

This study examines 20 years of recruitment in the NACC Uniform Data Set (40+ centers) and how participant profiles have changed over time.

💡 Read it here: alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

#HealthData #Generalizability

Chronic pain prevalence and trends in urban, suburban, and rural areas among American adults aged 55+, 1998–2022 Rural-urban health disparities in the United States are large and persistent, yet most surveillance efforts focus on mortality and disability. Monitor…

🔁 ICYMI: TIME-AD’s new publication, led by Dr. Yulin Yang, uses pain as a key marker to assess rural-urban population health in the United States.

Read it in Social Science & Medicine: www.sciencedirect.com/science/arti...

In celebration of #WorldHumanRights Day, the United Nations asked: what are your Everyday Essentials that are made possible by human rights in practice?

Our answer? Science, research, and healthy brain aging.

#HumanRights #HealthyAging #EverydayEssentials
@undecadeageing.bsky.social

📊 Social stressors, such as financial strain, are linked to lower cognitive function.

🔗 Led by Ruijia Chen, TIME-AD used cross-national comparisons to explore the individual and joint impact of five key stressors on cognitive health: tinyurl.com/yf5t3due

🔬 Audrey Murchland, PhD explores whether community-level social capital is associated with dementia risk, either directly or through its impact on social isolation.

🔗 Read about her research here: www.time-ad.org/audrey-murch...

#TIMEAD #ResearchReflections

Happening today!

Join us for the TIME-AD Fellowship Info Session and learn how to get involved in impactful AD/ADRD research this spring.

🗓 Today - December 4
🕐 1:00–2:00 PM
📍 Room L-203

All master’s-level BU students are welcome!

🌎 International Day of Persons with Disabilities

Sensory health is closely linked to dementia risk. TIME-AD is studying how sensory impairments and their treatment influence dementia, and whether addressing sensory loss reduces dementia incidence 🦻

Learn more: www.time-ad.org/projects/sus...

🎥 TIME-AD is coming to TikTok! From key findings to behind-the-scenes moments (and a few viral trends), we’re making dementia research easier to understand.

📱Follow us: tiktok.com/@timead2025

#DementiaResearch #TikTok

Thinking about getting hands-on research experience this spring?

Join our Fellowship Info Session next week to learn how you can get involved with TIME-AD!

📅 Dec 4, 1–2 PM
📍 Room L-203

Open to BU master’s students!