Sally Lowell's Avatar

Sally Lowell

@cellysally.bsky.social

Developmental & stem cell biologist, University of Edinburgh Digs repetition Also digs local coordination between cells in development and disease #SustainableConferencing #Music #Science #MoreScience Mastodon @CellySally@biologists.social

2,400 Followers  |  1,212 Following  |  172 Posts  |  Joined: 30.12.2023  |  1.7683

Latest posts by cellysally.bsky.social on Bluesky

...oh, sheer delight

26.11.2025 11:58 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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N2B27 media formulations influence gastruloid development Highlighted Article: This work explores the cellular and molecular sensitivity of the mouse gastruloid model system to variations in N2B27 media formulations, highlighting the need for careful media s...

I do like the @dev-journal.bsky.social "Research Report" format for shortish papers

This one is valuable. "Is it the N2B27?" is the stem cell biologist version of "Is it the magnesium?"

Congrats Tina Balayo @dias-andre.bsky.social David Turner & all authors
journals.biologists.com/dev/article/...

25.11.2025 11:21 β€” πŸ‘ 20    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
Dead Or Alive - You Spin Me Round (Like a Record) (Official Video)
YouTube video by DeadOrAliveVEVO Dead Or Alive - You Spin Me Round (Like a Record) (Official Video)

Wow! This one definitely needs a #PaperThemeTune. Congratulations to all authors!

youtu.be/PGNiXGX2nLU?...

21.11.2025 18:37 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
How sustainable is your event?

Find out with our new event carbon calculator 

The Company of Biologists logo to the left

How sustainable is your event? Find out with our new event carbon calculator The Company of Biologists logo to the left

🌱During #COP30, we invite you to explore what is the carbon footprint of an event and learn about easy steps to take to minimise it.
🟒Learn more with our free event carbon calculator: biologists.com/sustainabili...

14.11.2025 10:26 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Volume 152 Issue 20 | Development | The Company of Biologists

Development that lasts a life time. Check out the 2025 special issue of @dev-journal.bsky.social on Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues

journals.biologists.com/dev/issue/15...

05.11.2025 08:54 β€” πŸ‘ 28    πŸ” 15    πŸ’¬ 0    πŸ“Œ 0

It was such a pleasure to host @joadelas.bsky.social at @edinuni-irr.bsky.social yesterday. What a great talk- fascinating insights into how Cis Regulatory Elements process spatial and temporal information to build complicated and beautiful things such as embryos. Bravo Joaquina!

31.10.2025 09:06 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I'm so sorry. What terrible shocking sad sad sad sad news. So sorry.

30.10.2025 16:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

πŸ˜ƒ

30.10.2025 08:16 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Go to sleep in London, wake up in Edinburg! Great experience aboard the Caledonian Sleeper train.

Looking forward to a fun day full of science at the CRM. Thank you so much @cellysally.bsky.social for hosting me.

30.10.2025 08:08 β€” πŸ‘ 14    πŸ” 1    πŸ’¬ 1    πŸ“Œ 1
workflow image

workflow image

Read the 1st prize winning essay from our competition 'Innovative ideas for the future of sustainable events'. Read Liew Yao Rong’s essay and learn about his innovative approach that combines participants’ management, location and logistics: www.biologists.com/stories/peop...

28.10.2025 08:15 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Thank you @scholarlykitchen.bsky.social for featuring our Event Carbon Calculator in your article.

Read more for many great #sustainability tips.

28.10.2025 10:59 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
The Beta Band - 09 Push it out
YouTube video by Awkadan The Beta Band - 09 Push it out

www.youtube.com/watch?v=Eof4...

23.10.2025 08:56 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Developmental Biology and Disability - the Node Hopeful monsters. Morphospace. Mutation. Natural variation. Mutagenesis screens. Polymorphism. Deformity. Phenotype. Disease. Adaptation. Anomaly.

β€œDevelopmental biology is fundamentally beautiful. We are no less beautiful for our variation. Instead, perhaps we are more so. Perhaps we are remarkable. Perhaps we are full of wonder.”

Read this insightful post by Bethan on the Node.

thenode.biologists.com/developmenta...

#Disability

22.10.2025 13:15 β€” πŸ‘ 37    πŸ” 16    πŸ’¬ 0    πŸ“Œ 1

The Possible vs. The Actual: can #GenerativeBiology reveal fundamental design principles of complex life?

@philipcball.bsky.social closes #GenBio25 with a magnificent synthesis of the past two days of discussions, and guides us towards an agenda for the future of the field.

21.10.2025 17:43 β€” πŸ‘ 11    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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a herd of sheep walking down a grassy path ALT: a herd of sheep walking down a grassy path

Good afternoon #GenBio25. @bensteventon.bsky.social uses a flock of sheep as an analogy for multi-level reciprocal interactions between cells and how to engineer them.

20.10.2025 12:53 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Enabling neighbour labelling: using synthetic biology to explore how cells influence their neighbours Summary: This Primer reviews emerging approaches for engineering synthetic signalling between cells and discusses how these could be applied to study the influence cells have on their neighbours durin...

Who are our (cellular) neighbours? @matt-mala.bsky.social is addressing this question now at #GenBio25, using characters living on a conceptual β€˜Cell Street’. Learn more in his @dev-journal.bsky.social Primer: doi.org/10.1242/dev....

20.10.2025 08:44 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Transitions in development – an interview with Berna Sozen Berna Sozen is an Assistant Professor in the Department of Genetics at Yale University, USA. Berna's lab studies early mammalian development, metabolism, and maternal–fetal interactions using mouse an...

Good morning from Generative Biology! @bernasozen.bsky.social starts by taking a closer look at metabolism in early embryogenesis.

Learn more about stem cell-based embryo models in her recent @dev-journal.bsky.social Review: doi.org/10.1242/dev.... and interview: doi.org/10.1242/dev....

20.10.2025 08:12 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1

Three short talks now at #GenBio25. @bracciolilab.bsky.social discusses the ability of cells to contribute to different lineages in a gastruloid model. Luca recently published an β€˜In preprints’ article in @dev-journal.bsky.social: doi.org/10.1242/dev....

20.10.2025 10:57 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

We are looking forward to spending the next two days discussing INTERESTING THINGS at our workshop on Generative Biology: new approaches to study developmental design principles #GenBio25

Thanks to my excellent coorganisers @jcornwallscoones.bsky.social & @dbenzinger.bsky.social & all participants

19.10.2025 17:00 β€” πŸ‘ 15    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

BREAKING🚨: @Equinor has resubmitted its application to open the biggest undeveloped oil field in the UK - Rosebank.

In the next weeks, the UK gov will decide to reject or approve this disaster project.

Equinor hasn’t given up, and neither will we. We’re stepping things up.

15.10.2025 11:26 β€” πŸ‘ 150    πŸ” 103    πŸ’¬ 8    πŸ“Œ 16

An inspiration to so many of us. I can say with no hesitation that reading John Gurdon's papers as an undergraduate changed my life. I was reprogrammed from a slightly bored biochemistry student into a person with a life-long love of developmental biology. I have much to thank him for.

07.10.2025 17:15 β€” πŸ‘ 21    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

With storm Amy approaching, it’s an ideal time to get your SLiPERs on!

03.10.2025 15:38 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4 - Nature Communications Here they perform a systematic dissection of OCT4 and reveal how intrinsically disordered regions can be used to serve specific functions during reprogramming and embryonic development. This can be exploited to engineer more efficient and specific reprogramming factors.

Hot off the press!

Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4

www.nature.com/articles/s41...

30.09.2025 16:16 β€” πŸ‘ 30    πŸ” 12    πŸ’¬ 1    πŸ“Œ 1
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Brachyury expression levels predict lineage potential and axis-forming ability of in vitro derived neuromesodermal progenitors Neuromesodermal progenitors (NMPs) produce the spinal cord and musculoskeleton in the elongating anterior-posterior axis. In vivo, NMPs possess dual potency, coinciding with regions coexpressing SOX2 ...

Nice work from Val Wilson & co on neuromesodermal progenitors

SOX2/TBXT co-expressing cells are self-propagating bipotent NMPs

Increasing TBXT levels (not SOX2/TBXT ratio) switch NMPs from neural- to mesoderm-biased

www.biorxiv.org/content/10.1...

29.09.2025 08:33 β€” πŸ‘ 27    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
Post image Post image Post image Post image

Ever thought about exploring Stem Cells in different fields of biomedical research while surrounded by the beauty of a Greek island? That's exactly what the European Stem Cell Summer School offers – an inspiring learning experience on the outstanding island of Spetses πŸ‡¬πŸ‡· @stemcellsummer.bsky.social

21.09.2025 11:47 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 3    πŸ“Œ 0
Post image

An image analysis toolkit to streamline the study of cell fates in embryo development

Image made with @leicamicrosystems.bsky.social microscopy

πŸ“· Matthew French et al @cellysally.bsky.social lab University of Edinburgh in @plosbiology.org

➑️ bpod.org.uk/archive/2025...

16.09.2025 16:30 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
BPoD | Following Fate Following Fate - Biomedical pictures for September 2025.

Very excited to have this back-end-of-an-embryo cell-neighbour-analysis image from our latest paper featured as today's Biomedical Image of the Day!

Congrats to first author and ace image-analyst Matthew French

bpod.org.uk/archive/2025...

16.09.2025 12:29 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Writing challenge

the Node logo to the left

Post on the Node before 30 September and win Β£200 to the right

Writing challenge the Node logo to the left Post on the Node before 30 September and win Β£200 to the right

πŸ‘€ Do you have an idea for a post on the Node that you have been postponing writing for a while? This is your chance to publish your piece at last for a chance to win Β£200. Submit your post by 30 September 2025. πŸ“

thenode.biologists.com/the-node-wri...

#devbio #stemcell

16.09.2025 12:16 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
A slide displaying an image of a whisky distillery plus a list of 22 specialist biological terms, some from the stem cell and developmental biology field. These include transcription factor,  central doga, gastrulation, stem cell niche, mRNA, flow cytometry, chromatin, cell culture, and more.

A slide displaying an image of a whisky distillery plus a list of 22 specialist biological terms, some from the stem cell and developmental biology field. These include transcription factor, central doga, gastrulation, stem cell niche, mRNA, flow cytometry, chromatin, cell culture, and more.

The Scientific Distillery

Could you distil a complex scientific concept so that it can be explained in 30 seconds and be understood by a lay person, but *without* sacrificing scientific depth?

The delegates at #SCSS2025 were brilliant at this task πŸ‘

16.09.2025 10:44 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

@cellysally is following 20 prominent accounts