Dr Julia Marchingo

Very excited our work out in @jem.org “Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection”
@wehi-research.bsky.social led by talented (and determined) PhD student @benjbroom.bsky.social
Thread below.

Check out this super cool paper from @lindavsinclair.bsky.social and co which defines the fundamental timing, triggers and targets of autophagy in T cells!

🚨spoiler alert: they're not what most of the T cell literature says they are!

Hello Friends, I created a 5th #immunology Starter Pack. If you're an immunologist and you don't see yourself on the lists, let me know 🧪

go.bsky.app/PY5tCas

go.bsky.app/FmERUoD

go.bsky.app/6aT6qDS

go.bsky.app/QSEPDoj

go.bsky.app/Mdbpk7h

Research Officer Job Title Research Officer Job Description An excellent opportunity is available for a Research Officer to join the Groom Laboratory in the Immunology Division at Australia’s pre-eminent biomedical re...

Kicking off the new year searching for a postdoc to join our team @wehi-research.bsky.social
Apply now and spread the word

Nutrient-driven histone code determines exhausted CD8+ T cell fates ACLY-deficient CAR T cells targeting the tumor-associated antigen disialoganglioside GD2 (GD2 CAR T cells) also resisted acquiring TEX-like properties, exhibiting reduced CD39 expression when co-cultu...

Here is link to Shixin's new paper: www.science.org/doi/epdf/10....

SERVICE UPDATE

We normally don't ask you to "share like and subscribe" but please distribute this.

You are now able to delete the link after it embeds on your post so you can get those precious extra characters, and we will catch your post mentioning research.

#AcademicSky #Medsky #HigherEd

🎉 I'm a #newPI , and I'm so excited to share our new paper out in Nature Comms today! 🧵
rdcu.be/d2gBV
Quick intro for the new followers:
I'm from Monash Uni in Melbourne, and we study T and B cell responses to viruses, bacteria & parasites with the goal of improving vaccines. #ImmunoSky #MicroSky

WEHI - The Sir Gustav Nossal Professor of Immunology - Alumni Global The Professor will lead transformative research into the complexities of the immune system, building on Sir Gustav Nossal’s pioneering work. By fostering a culture of scientific excellence and innovat...

📢 World-leading Immunologists. The Nossal Endowed Chair of Immunology has just been announced @wehi-research.bsky.social. This is your chance to move (or return) to Australia to do ground-breaking research and join a thriving environment for discovery and translation.

(Bicentenary) ILC interactions with the extracellular matrix in inflamed barrier tissues at The University of Manchester on FindAPhD.com PhD Project - (Bicentenary) ILC interactions with the extracellular matrix in inflamed barrier tissues at The University of Manchester, listed on FindAPhD.com

New PhD opportunity in the lab with @profjudiallen.bsky.social and @douglaspdyer.bsky.social looking at interactions between ILCs and the extracellular matrix. Application deadline Jan 10th 2025 - spread the word Bluesky immunologists!
www.findaphd.com/phds/project...

Sectarianism in immunology.

(highly specific for immunologists, all credit to @pedromics on X)
1/8

Calculating and Reporting Coefficients of Variation for DIA-Based Proteomics The coefficient of variation (CV) is a measure that is frequently used to assess data dispersion for mass spectrometry-based proteomics. In the current era of burgeoning technical developments, there ...

My perspective on CVs for DIA-based #proteomics is out in JPR

It explores how normalisation, the CV formula and software parameters affect the outputs. It suggests parameters to use for biological and technical studies and provides an R package to calculate CVs.

doi.org/10.1021/acs....

I spend a bit of time talking to folk with plasma cohorts about MS vs affinity approaches for discovery. Thought it was worth a thread.

Most love the marketing. 5,000 proteins? 10,000 proteins? OLink was used in UK Biobank? Wow, mass spec is sooooo last year. Except life is not that simple.

I'm new here and very excited about this work. So please forgive me for posting, re-posting and replying lots. Big congrats to @virotuned.bsky.social, Nathan Croft and Tony Purcell - the main crew who made this happen. #immunology, #virology, #poxvirus,

Friends, the second #immunology starter pack filled in 3 days! I started a third to help folks new to BlueSky rebuild their network

Below are the links

If you're an immunologist and I have missed you so far, let me know 🧪

go.bsky.app/PY5tCas

go.bsky.app/FmERUoD

go.bsky.app/6aT6qDS

I made a starter pack for those of us interested in or working on T cells. Let me know if you would like to be added or know somebody that should be added.

Looking forward to scientific discussions and updates on our favorite immune cell type!

One of the good perils about #TeamMassSpec being active again is, it takes a while to go through all the posts and links..

The side-by-side comparison of volcano plots showing how different the protein differential expression analysis is based on the normalization strategy employed is awesome..

1/ After 3 years long years, our proteomic analysis of human stem cells is finally out. We reveal key differences between human induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs)—and show why normalisation is crucial. 🧪

Full paper: elifesciences.org/articles/92025

Wonderful to see the #immunology community growing here.

The first starter pack is full (they cap at 150), so I created a second one. Let me know if you'd like to be added

go.bsky.app/PY5tCas

go.bsky.app/FmERUoD

Hi, y’all! Looking for a better space to share/follow awesome science. 🧬 I’m a postdoc working with @sunnyshinlab.bsky.social on some cool biology at the intersection of immunometabolism, innate immunity & cell death. Also a proud mentor to 19 awesome undergrads through the PennFERBS program! 🥼

Intravenous and intracranial GD2-CAR T cells for H3K27M+ diffuse midline gliomas - Nature We evaluated the use of chimeric antigen receptor-modified T cells targeting GD2 (GD2-CART) for H3K27M+ diffuse midline glioma (DMG), finding that intravenous administration of GD2-CART, followed by i...

Listen up 👂
It's hard to over-hype this paper from Michelle Monje and Crystal Mackall on cellular therapy for #DIPG, a fatal childhood brain cancer.

It's not a perfect therapy; doesn't always work. By goodness, what progress we are making!

#CanSky
#MEDsky
#PedCanSky

www.nature.com/articles/s41...

A group of academics wearing white lab coats in a research Institute. Some are sitting. Some are standing. Everyone is smiling.

We’ve had a load of new followers on here in the last 2 weeks 😊🙌😊
So an introduction…

We are the Pallett lab - a fantastic, energetic & talented group of researchers interested in how tissue resident immune cells adapt to survive & function in the human liver

#liverSky #immunosky

🙋🏻🙋‍♀️🙋🏾‍♂️

Check out this cool new #microglia #proteomics resource!

Lots of lovely data for folks interested in #Immunology and #Neurodegeneration!

It has proteome data for ex vivo AND in vitro mouse AND human microglia AND in vitro h-ESC microglia that were xenografted!

Congrats @amylloyd.bsky.social !!!

Beyond that find ppl you know, look down their follow list for relevant ppl. I'd fill out your description a bit first so ppl know who they're following back. Beyond that use of the #immunosky means you reach a relevant audience to organically grow a relevant follow/(er) community over time

Hi Steve! The easiest way to build a relevant following is to get added to a starter pack. For Immunology you want this one set up by @rodrahimi.bsky.social. Not sure if this list is already full? go.bsky.app/PY5tCas

Interested in #Immunometabolism? Here's a small starter pack of some great people to follow here on Bluesky!

If you'd like to be added, please let me know :)

go.bsky.app/MvxkA4Q

Could I get an add too? Thank you for putting this pack together!

Waves of new BlueSky arrivals in last few days!

I’ve been tracking starter packs relevant to molecular/mechanistic/genetic/cellular…etc biology

Hope it’s helpful but warning: now a v long thread!

Probably the last time I can do this...

📢Intro post. I'm a postdoc at the Centre for Inflammation Research in Edinburgh.

My focus is on using mini-bulk and single cell proteomics to functionally characterise human neutrophils (and other leukocytes) in health and inflammatory disease. My content is a mix of proteomics and immunology. 🧪

Scientists in Proteomics Starter Pack! 🧪

go.bsky.app/3XETWrh

Got suggestions? Drop them in the comments!

Thanks to everyone who was in touch over the weekend with links to starter packs for cell/molecular/mechanistic biology.

A short thread to summarise.

Should give newcomers and old-timers some new names to follow.

There's certainly room for more, so keep them coming…