Gerry Hammond

Cool new paper (www.jbc.org/article/S002... from my lab spearheaded by graduate students Sushant @sushantsuresh.bsky.social and Alex @alexlouiseshaw.bsky.social . This was a very cool collaboration with the Scott Hansen, Jennifer Cobb, Tamas Balla labs

Channeling my Robert Millikan!

So much looking forward to get going!

Tenure-track Position in Biophysics at Carnegie Mellon University, Department of Physics Location: Pittsburgh, PA Open Date: Sep 19, 2025 Description The Department of Physics at Carnegie Mellon University invites applications for a tenure-track faculty position in biophysics. The appointment is intended to be at the Assistant Professor level, but exceptional candidates at a higher level may also be considered. We seek outstanding candidates with a strong record in cellular and subcellular biophysics. Topics of particular interest include, but are not limited to, uncovering how key characteristics of living systems arise from the interplay between supramolecular cellular structures, how the emergent cellular circuitry defines goals and enables robust decision making, and how metabolic resources are allocated. This encompasses understanding of how information is learned, stored, transduced, and processed across subcellular structures. Applicants with theoretical, data science, or experimental backgrounds within biological physics are encouraged to apply. The ideal candidate will strengthen and extend research programs of current biophysics faculty in the Department of Physics and collaborate with broader life science activities across many departments at CMU and the wider Pittsburgh area. More details on Interfolio: https://apply.interfolio.com/174360

I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪

Interfolio link: apply.interfolio.com/174360

PLEASE, share widely across the blue skies!

Let me briefly explain what we're looking for:

1/10

Josh Morgan discusses how progress in cell biology is hindered by significance testing and the need for a shift to effect size estimation. rupress.org/jcb/article/...

📕 In #Reproducibility and Best Practices in Cell Biology: rupress.org/jcb/collecti...

Always good to read JB and his lab's insights into one of the most important cancer targets, especially with their incredibly clear illustrations. So simple a basic cell biologist can follow it!

The plasmids are available on addgene now.

Note, we did control for competition with an endogenous PA effector (Nir2). However, your mileage may vary – like ethanol, too much PILS-Nir1 may impair your cells’ ability to signal via PA 😂

Announcing our new PA biosensor, PILS-Nir1 – seen here in HeLa cells during PLC activation #lipidtime #phospholipids

Read the OA paper in JCB

How do swelling lysosomes not burst? Because they literally suck more lipids into their membranes from the ER via this protein straw. Amazing piece of this particular molecular puzzle from my colleague jay tab!

This is such a beautiful mechanism for #phosphoinositide mediated regulation of integral membrane protein. Highly recommended #lipidtime read!!

This is the author of an eye-opening paper - tracking back through evolution to figure out the still very enigmatic function of a lipid kinase. It’s changed my view on these enzymes, and leaves me with many questions. That's what all the best papers do!

Congratulations!

Structural basis of lipid transfer by a bridge-like lipid-transfer protein - Nature The LPD-3 complex structure reveals protein–lipid interactions that suggest a model for how the native LPD-3 complex mediates bulk lipid transport and provides a foundation for mechanistic studies of ...

Whoa! Your weekend #lipidtime read: Our best view yet of lipids flowing along a bridge. Stunning work! If only we could see the “one-way” sign…

www.nature.com/articles/s41...

The inage is flier for the session stating the 9 am start and room number W179

The last #lipids and membranes session at #asbmb25 starts at 9 am. Hear everything you didn’t know about the biology of neurodegeneration!

Flier stating you can find out how lysosomal lipid BMP is really made

Join us for a firecracker of a #lipids and membranes session on lysosomal lipids at 9 am tomorrow #asbmb25

Delegates line up to grill the speaker

They’re lining up to learn more after @wumin-lab.bsky.social gave a fantastic talk on dynamic PI signaling in the opening #lipids and membranes session at #asbmb25!

Emma speaks at the podium

Emma Drew from U Oregon giving an amazing talk in the first #lipids and membranes session at #ASBMB2025. Single molecule experiments to show real time activation of a lipid phosphatase 🤯

Volker Haucke kicks off our #lipids and membranes theme at #ASBMB25! Fantastic session

And I am giving a talk tomorrow morning #asbmb25! Cheers Batman

A view of the massive and packed auditorium

Excited for the start for #ASBMB25!

This poster has the ASBMB logo and a molecular model of the cell, with the room number W179 and time, Sunday 9 am

We have some #lipids talks at #asbmb25 on PI signaling that will blow your mind! Join us Sunday at 9 a.m. in room W179

📣For lipid-focused sessions at #ASBMB25, add the symposium on #lipids and membranes, organized by @gerryhammond.bsky.social of the University of Pittsburgh and @judisimcox.bsky.social of the University of Wisconsin–Madison, to your schedule: www.asbmb.org/annual....

Image of three covers of Journal of Cell Science

Did you know…
It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳
For details, visit our website:
journals.biologists.com/jcs/pages/re...

A photo of Robert Helsley with text that reads Walter A. Shaw Young Investigator Award in Lipid Research.

Matching dieticians & shoppers at risk for #cardiovasculardisease is just one of the innovative clinical trials Robert Helsley, Shaw Award winner, has managed: ow.ly/vSqF50VxLUH.
➡️Attend his lecture at #ASBMB25 at 2:25 p.m. CDT on 4/15: ow.ly/jOQh50VxLUI.
#Lipids

A photo of Judith Storch with text that reads Avanti Award in Lipids.

Judith Storch won the Avanti Award in #Lipids. Her lab studies lipid traffic in cells, w/emphasis on the proteins that bind long-chain fatty acids, monoacylglycerols & #cholesterol.
ow.ly/GK6K50VxOy4
➡️Attend her lecture at 1:50 p.m. CDT on April 15: ow.ly/HEsg50VxOy7.
#ASBMB25

Pls re-skeet! There's a postdoc job available to join us in Bristol! We're looking for a molecular cell biologist to help us investigate plasma membrane proteostasis in neurons. Apply here by 23 April: www.jobs.ac.uk/job/DMO097/r.... If interested, do contact me and check out grieve-lab.com! Thanks!

I am beyond thrilled to co-organize this FASEB #LipidDroplet conference with Mike @hennelab.bsky.social in 2026! Check out the lineup and plan to participate - you do not want to miss this one!! #lipidtime

If you're heading to Chicago for the #ASBMB annual meeting, we have many #lipidtime treats for you!

Here's one: want to know the real pathway for BMP synthesis? Check out this session on Monday 4/14 at 9 am:

@judisimcox.bsky.social chairing

events.rdmobile.com/Sessions/Det...

P4-ATPase control over phosphoinositide membrane asymmetry and neomycin resistance Neomycin, an aminoglycoside antibiotic, has robust antibacterial properties, yet its clinical utility is curtailed by its nephrotoxicity and ototoxicity. The mechanism by which the polycationic neomyc...

The antibiotic Neomycin is too nephrotoxic and ototoxic to use systemically. Why is a decades-old mystery...

Until now, with a sure-to-be classic from the Graham lab at Vanderbilt. It’s all about #phosphoinositides 🤯

Your #lipidtime weekend read

www.biorxiv.org/content/10.1...

Lipid Research Division Seminar Series March 26, 2025 | 12 p.m. Eastern

Join us March 26th at 12pm ET - @asbmb.bsky.social LRD seminar series.

We have two great mitochondria-focused lipid talks planned from @jasoncasler.bsky.social from @lllackner.bsky.social's lab and Kailash Venkatraman from @ibudin.bsky.social's lab.

Register here! www.asbmb.org/meetings-eve...