David Peede

The Length of Haplotype Blocks and Signals of Structural Variation in Reconstructed Genealogies Abstract. Recent breakthroughs have enabled the accurate inference of large-scale genealogies. Through modelling the impact of recombination on the correla

Delighted that our paper about the distribution of genomic spans of clades/edges in genealogies (ARGs), and using this for detecting inversions and other SVs (and other phenomena that cause local disruption of recombination) is out in MBE academic.oup.com/mbe/article/... (1/n)

03.10.2025 09:54 — 👍 65    🔁 38    💬 4    📌 1

Hybridization and introgression are major evolutionary processes. Since the 1940s, the prevailing view has been that they shape plants far more than animals. In our new study (www.science.org/doi/10.1126/...
), we find the opposite: animals exchange genes more, and for longer, than plants

12.09.2025 07:54 — 👍 200    🔁 120    💬 3    📌 3

The MUC19 gene: An evolutionary history of recurrent introgression and natural selection We study the gene MUC19, for which some modern humans carry a Denisovan-like haplotype. MUC19 is a mucin, a glycoprotein that forms gels with various biological functions. We find diagnostic variants ...

An extraordinary story of archaic introgression🧬: a Denisovan haplotype, introgressed through Neanderthals, selected in the Americas, and linked to an expanded copy number of a tandem repeat.
Congrats to @david-peede.bsky.social, Emilia, and the whole team!
👉 Enjoy the read: doi.org/10.1126/scie...

01.09.2025 17:31 — 👍 6    🔁 1    💬 0    📌 0

I am so happy to see this fantastic study finally published! Huge congrats to @david-peede.bsky.social , @fervillanea.bsky.social , and all the co-authors. Amazing work! 😍

01.09.2025 10:24 — 👍 5    🔁 1    💬 0    📌 0

Thrilled to see this paper on MUC19 out. I feel honoured and priviledged to have witnessed this amazing project unfold. Read @fervillanea.bsky.social ’s thread and be prepared for a jaw-dropping story on introgression and selection, and best of all… in Native and Admixed Americans!!

22.08.2025 05:35 — 👍 15    🔁 4    💬 1    📌 0

The MUC19 gene: An evolutionary history of recurrent introgression and natural selection We study the gene MUC19, for which some modern humans carry a Denisovan-like haplotype. MUC19 is a mucin, a glycoprotein that forms gels with various biological functions. We find diagnostic variants ...

Our paper on the evolution of MUC19 in humans, Neanderthals, and Denisovans is finally out today in Science!

This has been a six-year effort by 13 authors to weave together 3 separate but related evolutionary stories around this one gene (more on thread 🧵).

www.science.org/doi/10.1126/...

21.08.2025 19:36 — 👍 106    🔁 48    💬 6    📌 4

@david-peede.bsky.social et al on the convoluted route of a variant of the MUC19 gene: Denisovans (before going extinct) passed the gene to Neanderthals, who (before going extinct) passed it to ancient humans, who then crossed the Bering Strait. Today, 1 in 3 Mexicans carry the genetic variant.

21.08.2025 19:05 — 👍 16    🔁 7    💬 2    📌 1

It’s UNREAL 🤯 what imputation can reveal about archaic Introgression across space 🌎 and time ⏳, and I'm personally STOKED 🤩 to see what the imputation era of archaic introgression will uncover 👀

24.07.2025 16:16 — 👍 5    🔁 1    💬 0    📌 0

Text: Virtual Evolution 2025. Society for the Study of Evolution Hamilton Award Symposium. Thursday, May 29, 1:30 PM - 7:30 PM Eastern (GMT-4). 2025 Finalists: Meaghan Clark, Dylan DeBaun, Devon DeRaad, Simon Innes, Josh Knecht, Kip Lacy, Gina Lamka, Prothama Manna, Gemma Martinez-Redondo, David Peede, Gabriel Preising, Jeremy Summers, David Tian, Matthew Treaster, and Amanda Vieira da Silva.

Congratulations to this year's Hamilton Award finalists! 🎉 Join us Thursday, May 29 to hear these outstanding student talks. See the full schedule on the meeting website: www.evolutionmeetings.org/program-over... @evolmtg.bsky.social

22.05.2025 07:22 — 👍 40    🔁 21    💬 0    📌 1