Pam Rosato

David Baltimore, Nobel Prize-winning scientist and former Caltech president, dies at 87 Baltimore played a role in virtually every important national debate over the use and potential misuse of the science of genetic engineering.

www.latimes.com/obituaries/s... RIP David Baltimore. A true giant of biomedical research. Made so many fundamental discoveries: Reverse transcriptase; NF-kB; Rag genes (among others) Also shut down his lab for a week in 1970 to protest the US invasion of Cambodia.

I applaud workers at the CDC for standing up against Sec. Kennedy’s dangerous anti-vaccine crusade.

We are witnessing a full-blown war on public health from the Trump Administration.

History will not look kindly on those who stayed silent in the face of this assault on science.

Many of us have long been worried about the harm of the 50% multiyear funding (MYF) requirement.

When NCI published their payline at 4% AND cited MYF as the cause, I thought: “Someone in NCI is a hero. They took a huge risk to make the community aware.”

www.cancer.gov/grants-train...

Columbia University’s agreement with the Trump administration is a disaster for academic freedom, freedom of speech, & the independence of American higher education. Never in the history of our nation has an educational institution so thoroughly bent to the will of an autocrat.

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This critical new knowledge of how a major clinical therapy (2018 Nobel prize) works was made possible by multiple research, training & career development awards from NCI & NIAID & NCATS, which face ~40% cuts of >$8 billion jamanetwork.com/journals/jam...

How Trump’s D.E.I. Cuts Are Hurting Rural White Americans Too

“If you cut out these diversity measures, you're going to make science full of people that are very elite…Full of people who have grown up with a large amount of privilege, who were able to work in a lab in high school because their dad was a prof at Cornell.” 🧪

www.nytimes.com/2025/07/10/u...

THIS IS IT! THIS IS HUGE!!

PLAINTIFF'S WIN!!

Judge Young rules that the NIH grant terminations at issue in these cases are illegal and therefore vacated. BOOM!

🚨 BREAKING: Nearly 4 months the NIH cut its first grants, a judge has ruled that the directives and process that led to cuts are arbitrary and capricious.

"The explanations are bereft of reasoning — virtually in their entirety... unsupported by [facts]."

Each of them are VOID and ILLEGAL, he says.

An Uproar at the NIH Jay Bhattacharya, the the agency’s director, has made a point of welcoming dissent. A letter from his officials will test that.

Gift link to Atlantic article

www.theatlantic.com/health/archi...

Add your name in support alongside 20+ Nobel loreates and >8000 other scientists!

Photo of Dr. Bhattacharya speaking at a government hearing room, with the text “THE RECKONING BEGINS!” above. Text notes that he will appear before the Senate Appropriations Committee on June 10, where the Bethesda Declaration will be presented.

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TOMORROW: Bhattacharya appears before the Senate Appropriations Committee..

He’ll be confronted publicly with the Bethesda Declaration—an unprecedented rebuke by hundreds of his own federal employees.

HERE’S HOW YOU CAN HELP ➡️

Front-page-style graphic titled “BREAKING NEWS” with photos of RFK Jr. and Dr. Bhattacharya in front of a government hearing chamber. Text reads: “NIH Scientists Sound the Alarm as Health Research Faces Historic Threat” and “NIH Employees Send Trump Cronies Scathing Wake-Up Call.”

🚨BREAKING: 300+ NIH employees call out the harm of censorship & politicized science in scathing email to Bhattacharya, demanding an end to political interference, a lift on funding freezes, & rehiring of fired staff whose work saves lives.

This is historic - insiders are blowing the whistle.
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A word cloud made from flagged terms in terminated NIH grant proposals. The most prominent words in large font include “trans,” “diverse,” “diversity,” “minority,” “sex,” “expression,” “mental health,” “gender,” and “women.” Other visible terms include “LGBTQ,” “racial,” “underrepresented,” “disability,” “barriers,” “black,” “equity,” “health equity,” “vaccine,” “bias,” and “intersectionality.” The word cloud highlights terms related to identity, inclusion, and marginalized communities.

HAPPY PRIDE 🏳️‍🌈

Under Trump, research using terms like “Trans,” “LGBTQ,” & “Gender identity” is being defunded. These terms reflect real people who deserve science that includes them.

Stand with us to protect LGBTQ+ science from political erasure.
grant-watch.us/nih-data.html
@rcmedphys.bsky.social

The end of US leadership in science, technology, and innovation.

All in one little table.

A tremendous gift to China, courtesy of the GOP.

nsf-gov-resources.nsf.gov/files/00-NSF...

🚨ATTENTION MOMS🚨

Friday, May 30th at 3pm

Meet me outside of the CDC with your pregnant bellies, your babies, your toddlers, your strollers, your signs, and your baby gear.

We are standing up for science and vaccines!
@standupforscience.bsky.social

RSVP: actionnetwork.org/events/moms-...

💀💀💀

"Secretary, you spent nearly three decades as a WWE executive, where you orchestrated such spectacles as “The Undertaker vs. Kane: WrestleMania XIV” and “WWF Badd Blood: In Your House.” Suffice to say, you respect a good fight. And thus I say: Come at me, bro."

Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment @cp-immunity.bsky.social
www.cell.com/immunity/ful...

🚨 A new rule would let career scientists like NSF/NIH program officers be replaced by political appointees

Already 14,000+ public comments, deadline is Friday

📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful

Speak up! shorturl.at/WKuBj

SIGN UP: Press Connection Are YOU willing to speak to the press? Join the Summer Fight for Science Air Game by signing up to be a source for break science news stories. We will provide media training and keep your information ...

Great new tool to help folks volunteer to speak out and share information with the press (even on background, anonymously)

actionnetwork.org/forms/sign-u...

My ongoing request:

If your NSF or NIH grant was terminated--whether at Harvard or elsewhere--please report it here.

NSF: grant-watch.us/submit-nsf.h...

NIH: grant-watch.us/submit-nih.h...

Our trackers are actively used in lawsuits and are often the only record that terminations ever occurred.

Host a teach in. Share science with your community....protest style! Calling back to the teach ins of 1965, we are taking to parks, pubs, & churches to tell our neighborhoods about how the budget cuts will impact them.

Our goal is to have 1000 SUFS Teach Ins across the US, by 9/30.

*GASP* 😮

We know, it's a big goal.

If you've received tax dollars for your science, you have a responsibility to inform *your* community what is at stake: public health, the economy, innovation, and America's global leadership.

Summer Fight For Science 2025 — STAND UP FOR SCIENCE

Everything you need to execute your own teach in is at this link. Check the event guide, add it to Action Network, make some flyers, and get moving!

#StandUpForScience
#SummerFightForScience

www.standupforscience.net/summer-fight...

"Women are PIs on 58% of the canceled grants, although they are PIs on only 34% of all active NSF grants.

Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."

White privilege is being hired for a job you're not qualified to do, whining about DEI while screwing up again and again and again, and then being given extra time to "get it together" in the future.

Pallavi holding an award certificate.

Many congratulations to @pallavisgadgil.bsky.social for being awarded the Lucille Smith award for excellence in Biochemistry. This award is in honor of the memory of Dr. Lucille Smith. The first woman at Dartmouth to attain the rank of full professor!

When the moment came, Harvard didn’t hedge or flinch—it stood up. A reminder that integrity isn’t complicated, it’s just rare.

Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling The local immunoregulatory mechanisms that safeguard the host from excessive lung infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential role of nerve- and airway-associated...

Excited to share our latest study
@cp-immunity.bsky.social. Heartfelt thanks to the editorial and review teams , to my co-first @yeungadventures.bsky.social, our co-authors, and to @khannakm.bsky.social
for his outstanding mentorship throughout! Pls read/share!👇
www.cell.com/immunity/ful...

book display "on tyranny"

While certain college presidents don't seem to understand what's happening, at least our local bookstore does #StillNorthBooks

Harvard has set an example for other higher-ed institutions - rejecting an unlawful and ham-handed attempt to stifle academic freedom, while taking steps to make sure students can benefit from an environment of intellectual inquiry, rigorous debate and mutual respect. Let’s hope others follow suit.

A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals T cell priming is characterized by an initial activation phase that involves stable interactions with dendritic cells (DCs). How activated T cells receive the paracrine signals required for their diff...

"We propose that the initial T cell priming phase functions like an education phase...of a broad T cell repertoire. The second priming phase serves to promote the proliferation and differentiation of high-affinity CD8 T cell clones by coordinating paracrine signals" #Immunology