Adrian Saurin

I have multiple positions available to join my lab from this summer: #postdoc, #student and #technician. Adverts to follow but see www.saurinlab.com for further details. #senescence, #mitosis, #cellcycle, #phosphorylation are the key areas. Email me if interested.

To kickstart this new Bluesky account: We're hiring!
The Bertolin Lab @dundee.ac.uk is looking for a postdoc to work on DNA-end homeostasis & genome stability, funded by Wellcome Trust Award. Exciting science, fantastic environment, founding role in the lab.
Details in the flyer — get in touch! 👇

Last days to apply this position in our group! Do join us in this great Institute @crg.eu, with great colleagues, and help shaping the science and culture of our lab!

I watched much of Ian Chapman's (Head of @ukri.org) appearance this morning at @ukparliament.parliament.uk Science, Innovation and Technology Committee..

A few points and new information that bioscientists may find interesting...

A 🧵

Two new papers from the lab published in The EMBO Journal!

link.springer.com/article/10.1...
By Kai Walstein, @louisa-hill.bsky.social and others – On role of M18BP1 in CENP-A loading

link.springer.com/article/10.1...
By Arianna Esposito Verza and others – On mechanism of activation of PLK1

@ukri.org Could you please make a statement about whether this will impact on grants already in review from autumn 2025? It's hard to accept grant opportunities closing, but even harder to accept the rug being pulled after review. Rumours of a 1-5% acceptance rate would be incredibly hard to take

At a time when the UK should be capitalising on its global reputation as a great place to do science, this is an enormous own goal. I am so sorry for all those who jobs are going to be impacted.

PhD position in my lab!

Brooklyn Beckham and Prince Harry are the canaries in the coalmine. The children of Instagram will be next | Rhiannon Lucy Cosslett A generation of overexposed children are being used by their parents for social media clout. What happens when they start to speak out, asks Guardian columnist Rhiannon Lucy Cosslett

Wholeheartedly agree with this. Well said
www.theguardian.com/commentisfre...

Postdoctoral Research Assistant - UOD2127 Closing date: Wednesday 18 February 2026, 23:59

Please share! We've an exciting one-year postdoctoral position available in my group - drug discovery using HDX-MS for a Parkinson's disease target. Join us on high-impact, translational research at the cutting edge of structural biology. We're a friendly bunch! www.dundee.ac.uk/work-for-us/...

We are also recruiting a Postdoc in cell/molecular biology!

3yr, fully funded by @cancerresearchuk.org more details here: news.cancerresearchuk.org/2025/11/27/s...

Apply here: www.imperial.ac.uk/jobs/search-...

Group-based Prediction System (GPS) 6.0

gps.biocuckoo.cn

Online server for protein Post-Translational Modifications
Kinase-specific phosphosite prediction across 185 species!

>10 other PTMs

#NucAcidRes 2023
academic.oup.com/nar/article/...

We are back on Jan 19 at 3pm CET! Our first seminar for 2026 will feature Prof. Benjamin Turk (@benturklab.bsky.social) and Dr. Giorgia Massacci.

Register to attend: tinyurl.com/PMCseminar2

Previous seminars: www.youtube.com/@PMCModularity

YouTube video by The Diary Of A CEO AI Expert: We Have 2 Years Before Everything Changes! We Need To Start Protesting! - Tristan Harris

youtu.be/BFU1OCkhBwo?...

AI Expert: We Have 2 Years Before Everything Changes! We Need To Start Protesting! - Tristan Harris Podcast Episode · The Diary Of A CEO with Steven Bartlett · 27/11/2025 · 2h 23m

The best thing I’ve listened to all year. A brilliantly articulated vision about the dangers of AI which stresses the importance of societal pressure in demanding a safe future. Please consider listening and deciding for yourself if and how you can help

open.spotify.com/episode/1S8F...

The mitotic stopwatch limits the proliferation of whole genome doubled cells Whole genome doubling (WGD) is a frequent event in tumourigenesis that promotes chromosomal instability and tumour evolution. WGD is sensed indirectly due to the presence of extra centrosomes, which a...

2 recent preprints show the mitotic stopwatch monitors more than just mitotic delays - it protects against WGD, cell enlargement and other stresses that mildly activate p53. It may act to amplify p53 signals to suppress tumourigenesis

www.biorxiv.org/content/10.1...

www.biorxiv.org/content/10.6...

Cell Proliferation and Gene Editing Unit Every day, millions of cells divide to sustain essential tissue functions. Errors in this process can lead to developmental disorders or cancer. Our research focuses on the molecular mechanisms of cel...

We’re recruiting a Postdoctoral Researcher at OIST (Okinawa, Japan) to explore how mitotic stress shapes aging.

If you’re excited about cell biology, aging, and mechanistic discovery, we’d love to hear from you.

More info: www.oist.jp/careers/post...

Website: www.oist.jp/research/res...

I agree. And others offering ideas or help for work in progress would also be a step forward. We need to collaborate at the ideas stage much more and the internet could really help facilitate that.

Interesting. Looking forward to reading these…Congrats!

Last 3 days to apply for this post. Deadline 27/10/25

PhD student position in the Cell Signaling and Cell Cycle group at the Danish Cancer Institute. The Cell Signaling and Cell Cycle group, headed by Prof. Jakob Nilsson, is looking for a highly motivated and enthusiastic PhD student to establish novel CRISPR

I have a PhD opening in my lab for an exiting project using base editor screens to find novel drug targets. Please help spread the word. candidate.hr-manager.net/ApplicationI...

Nice to see that out. Congrats!

The model is based on the fact that paclitaxel binds strongly to microtubules. It could also be relevant for other cancer drugs that bind strongly to abundant cellular targets, such as microtubules or DNA

Seeing a loved one roll the dice with drugs like this (as too many of us will) really hits home how little we know. That was the inspiration to get this idea out. We must learn how these drugs work if we are going to improve on them

A perfusion-based model to explain how paclitaxel achieves tumour-selective killing Paclitaxel (taxol) is a commonly used chemotherapeutic that stabilizes microtubules to inhibit chromosome segregation during mitosis. Although it is used effectively to treat a wide variety of solid t...

A simple idea for how paclitaxel achieves tumour selectivity: It is better retained inside dense tissue, allowing tumour levels to stay high even after it has cleared the healthy cells. A model that requires testing, but could be used to improve treatments if correct
www.biorxiv.org/content/10.1...

End GDP mania: how the world should really measure prosperity The obsession with economic output as a measure of human development puts sustainability on the back burner. Researchers can now help to devise better indicators.

“We have economies that need to grow, whether or not they make us thrive; what we need are economies that make us thrive, whether or not they grow.”

www.nature.com/articles/d41...

a man in a plaid shirt sits in front of a couch with london written on it ALT: a man in a plaid shirt sits in front of a couch with london written on it

Wow, a recruitment bonanza in the current climate? Magic!

Description Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer.

Deadline 15th October. Get in touch if you have any questions.

Please repost!

More details:
www.imperial.ac.uk/jobs/search-...

depmap miner logo

The Garnett Lab is excited to launch DepMap Miner, a new tool to explore cancer dependency data!
Built on the Sanger DepMap, the DepMap Miner brings together multi-omic and functional datasets for over 1300 cancer cell models.

Start mining data now: dataminer.depmap.sanger.ac.uk

The mitotic stopwatch limits the proliferation of whole genome doubled cells Whole genome doubling (WGD) is a frequent event in tumourigenesis that promotes chromosomal instability and tumour evolution. WGD is sensed indirectly due to the presence of extra centrosomes, which a...

Very excited to post our latest work showing the mitotic stopwatch monitors more than just mitotic delays - it protects against whole genome doubling and cell enlargement.

Great work by fantastic postdocs Lindsey and Reece (& student Maria)
#PostdocAppreciationWeek

www.biorxiv.org/content/10.1...