Bae Mechanobiology Lab

Survivin in cardiovascular diseases and its therapeutic potential Aberrant changes in cell behaviors, such as proliferation, apoptosis, and migration, are some of the contributing factors to the development of variou…

I’m pleased to share our review paper, “Survivin in Cardiovascular Diseases and Its Therapeutic Potential,” published in Vascular Pharmacology. Congratulations to everyone who contributed to this review paper!

www.sciencedirect.com/science/arti...

Boarded the plane to Los Angeles. Looking forward to #BPS2025 !!

YouTube video by Yongho Bae Gryson Bae (violin) and Oliver Santora (piano)- Czardas - Winterfest 2024 50th Anniversary

I am excited to share that my son performed Czardas as a violin solo, accompanied by piano, at his high school's Winterfest. I know his performance wasn’t perfect, but I hope you enjoy it!

I hope everyone has a wonderful holiday season and a happy New Year!

youtu.be/8uEosn4JbQc?...

Survivin modulates stiffness-induced vascular smooth muscle cell motility Arterial stiffness is a key contributor to cardiovascular diseases, including atherosclerosis, restenosis, and coronary artery disease, it has been characterized to be associated with the aberrant mig...

I am pleased to share our latest study on cell motility, led by Thomas Mousso and Kalina Rice, titled "Survivin modulates stiffness-induced vascular smooth muscle cell motility."
doi.org/10.1101/2024...

Two students, Jessica Jong and Gabrielle Inserra from the Bae Lab will be giving poster and podium presentations at the #CellBio24 (ASCB|EMBO) meeting in San Diego. Please stop by and check out our latest studies.

Excited to share our bioinformatics study, published in IEEE Transactions on Molecular, Biological, and Multi-Scale Systems: 'Transcriptomic and Multi-scale Network Analyses Reveal Key Drivers of Cardiovascular Disease.'

ieeexplore.ieee.org/abstract/doc...

FAK and p130Cas Modulate Stiffness‐Mediated Early Transcription and Cellular Metabolism Cellular metabolism is influenced by the stiffness of the extracellular matrix. Focal adhesion kinase (FAK) and its binding partner, p130Cas, transmit biomechanical signals, such as substrate stiffne...

Delighted to share our new work in Cytoskeleton, led by my talented students (Bat-Ider Tumenbayar & Khanh Pham), featuring our RNAseq data that uncovers the mechanobiological roles of FAK & p130Cas in early transcriptional regulation and biological processes. onlinelibrary.wiley.com/doi/10.1002/...