Kumaran Ramamurthi's Avatar

Kumaran Ramamurthi

@ramamurthilab.bsky.social

Sock afficionado and scientist @NCI @NIH studying protein localization in bacteria. We also design artificial bacteria to deliver chemotherapeutics to #cancer cells. All views are my own. https://scholar.google.com/citations?user=t9UM04YAAAAJ&hl=en

1,198 Followers  |  864 Following  |  43 Posts  |  Joined: 30.09.2023  |  1.9692

Latest posts by ramamurthilab.bsky.social on Bluesky

Reposting because it’s Sunday and maybe people have time for a podcast today. It was really fun to with @markowenmartin.bsky.social about my group’s concrete project! (with bonus road salt content)
@sunyesf.bsky.social #microsky #concrete #builtenvironment

16.11.2025 14:51 β€” πŸ‘ 15    πŸ” 6    πŸ’¬ 2    πŸ“Œ 1
The Integration of eVTOL Aircraft and Infrastructure into San Jose Mineta International Airport - NASA Technical Reports Server (NTRS) With the average American spending around 43 hours a year sitting in traffic1, and automobile emissions in the US accounting for 57% of all transportation emissions2, traditional transportation infras...

ntrs.nasa.gov/citations/20...
Pretty cool high school project

15.11.2025 20:16 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
A fake spider in a web, with text: That’s no spider! It’s a decoy

A fake spider in a web, with text: That’s no spider! It’s a decoy

For the first time, scientists have documented an unusual defense: Some species of arachnids build giant doppelgΓ€ngers on their webs, creating a frightening deception that scares off would-be killers. https://scim.ag/487Myn0

12.11.2025 17:08 β€” πŸ‘ 183    πŸ” 65    πŸ’¬ 3    πŸ“Œ 9
Propulsion-independent surface migration in S. enterica LT2 and E. coli.

Propulsion-independent surface migration in S. enterica LT2 and E. coli.

#MicrobiologyMonday: Bacteria swarm, but DYK they also "swash"? This flagella-independent movement is tied to fermentation: as cells ferment sugars, they create local osmolarity gradients, which generate a wave of fluid driving expansion. #JBacteriology: asm.social/2Gh

10.11.2025 17:03 β€” πŸ‘ 32    πŸ” 9    πŸ’¬ 1    πŸ“Œ 1

My reviewing style has changed over time. Rather than litigate every little thing, and pushing my own ideas, I focus only on 2 things:
(1) Are the claims interesting/important?
(2) Does the evidence support the claims?

Most of my reviews these days are short and focused.

08.11.2025 11:22 β€” πŸ‘ 237    πŸ” 40    πŸ’¬ 7    πŸ“Œ 8
Video thumbnail

"Look again at that dot. That’s here. That’s home. That’s us. On it everyone you love, everyone you know, everyone you ever heard of, every human being who ever was, lived out their lives."

― Carl Sagan, born 9 November 1934

Video Credit: @planetarysociety.bsky.social

#PaleBlueDot πŸ”­ πŸ§ͺ #CarlSagan

09.11.2025 18:21 β€” πŸ‘ 105    πŸ” 37    πŸ’¬ 4    πŸ“Œ 1
smallthingsconsidered.blog

smallthingsconsidered.blog

Ray: Just a note to say STC is officially back up and running!! You can view our new home via smallthingsconsidered.blog

03.11.2025 01:10 β€” πŸ‘ 26    πŸ” 9    πŸ’¬ 0    πŸ“Œ 1
Post image

both are right: the best is marine microbiology

02.11.2025 17:47 β€” πŸ‘ 72    πŸ” 11    πŸ’¬ 1    πŸ“Œ 0
Preview
The stringent response does not influence ribosome pausing in Bacillus subtilis Abstract. The stringent response represses translation and is activated when cells enter the stationary phase and intracellular amino acid levels drop. Bac

The stringent response does not influence ribosome pausing in Bacillus subtilis

@narjournal.bsky.social from Leendert Hamoen

academic.oup.com/nar/article/...

01.11.2025 11:42 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Post image

These were the dinosaurs that faced the asteroid.

Some of the last survivors. They lived in New Mexico, 66 million years ago. Among them was Alamosaurus, the size of a jetplane.

We unveiled them, and their true age, today in a new paper in
@science.org !

23.10.2025 18:31 β€” πŸ‘ 106    πŸ” 16    πŸ’¬ 3    πŸ“Œ 5
Department Head, Department of Immunobiology Strategic LeadershipDevelop and execute a bold vision for the Department of Immunobiology that advances understanding of how immune and micr...

Come be my chair at The University of Arizona! We have great bike riding, hiking, and of course, science! arizona.csod.com/ux/ats/caree...

21.10.2025 15:42 β€” πŸ‘ 16    πŸ” 14    πŸ’¬ 1    πŸ“Œ 0

With the functional link!
journals.asm.org/doi/10.1128/...

21.10.2025 14:04 β€” πŸ‘ 9    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

Mandatory viewing for microbiologists...

17.10.2025 23:10 β€” πŸ‘ 9    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Episode 112 of #MattersMicrobial! Dr. Petra Levin joins the #QualityQuorum to discuss bacterial cell size, pH, and antibiotic sensitivity. PLEASE spread the #GoodMicrobialWord. Petra is inspirational. @univpugetsound @asmicrobiology @microbe.tv

youtu.be/YPNAvJYAq-s?...

17.10.2025 17:26 β€” πŸ‘ 13    πŸ” 8    πŸ’¬ 1    πŸ“Œ 2
Video thumbnail

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➑️ www.crick.ac.uk/careers-stud...

09.10.2025 14:06 β€” πŸ‘ 135    πŸ” 112    πŸ’¬ 1    πŸ“Œ 18
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783

07.10.2025 16:10 β€” πŸ‘ 19    πŸ” 30    πŸ’¬ 0    πŸ“Œ 3
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404

05.10.2025 12:03 β€” πŸ‘ 62    πŸ” 71    πŸ’¬ 2    πŸ“Œ 1
Preview
Effects of extreme acceleration, microgravity, and deceleration on Bacillus subtilis onboard a suborbital space flight - npj Microgravity npj Microgravity - Effects of extreme acceleration, microgravity, and deceleration on Bacillus subtilis onboard a suborbital space flight

Humans began travelling into space in 1961 with single orbits of the Earth. Now Bacillus subtilis!

πŸ‘‰

www.nature.com/articles/s41...

#subtiwiki

Thank you @joergstuelke.bsky.social for the reading recommendation!

06.10.2025 14:18 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Preview
(p)ppGpp-dependent activation of gene expression during nutrient limitation | mBio Bacteria often experience nutrient limitation and, in response, attenuate energetically costly metabolic processes like protein synthesis. At the same time, however, they stimulate the expression of a subset of proteins that facilitate survival under ...

(p)ppGpp-dependent activation of gene expression during nutrient limitation

#mBio from Jonathan Dworkin

journals.asm.org/doi/10.1128/...

19.08.2025 13:29 β€” πŸ‘ 6    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

"Cascading failure" is my new favorite term

28.09.2025 13:54 β€” πŸ‘ 9    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Preview
Five Tenure-Track Assistant Professor Positions in Microbiology, Evolution, and Biological Clocks - College Station, Texas job with Department of Biology - TAMU | 675062 Texas A&M University (TAMU) invites applications for five full-time, tenure-track Assistant Professor positions

We're hiring! 5 tenure track assistant professors. 2 #microbiology, 2 #Evolution, 1 #biologicalclocks

jobs.sciencecareers.org/job/675062/f...

12.09.2025 18:11 β€” πŸ‘ 29    πŸ” 43    πŸ’¬ 1    πŸ“Œ 1
Preview
Rich Losick’s Farewell Publication Reexamines a Molecular Biology Milestone - Harvard University - Department of Molecular & Cellular Biology Richard Losick, Maria Moors Cabot Professor of Biology, Emeritus in Harvard’s Department of Molecular and Cellular Biology, is about to publish what he describes as his β€œlast paper”—though […]

Rich Losick’s Farewell Publication Reexamines a Molecular Biology Milestone πŸ§ͺ 🧬 #AcademicSky #higherEd
www.mcb.harvard.edu/department/n... @cryptogenomicon.bsky.social @craigphunter.bsky.social @rachellegaudet.bsky.social @harvardmagazine.bsky.social @naoshigeuchida.bsky.social

11.09.2025 20:01 β€” πŸ‘ 18    πŸ” 14    πŸ’¬ 0    πŸ“Œ 2

Wonderful collaboration with labs of Kandice Tanner and David Fitzgerald, both at NCI, that really allowed our lab to pursue this very different (to us) line of research that begins to translate years of our basic studies in bacterial cell biology into an applied technology

12.09.2025 14:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Domenico surprisingly found that 1) particle size and 2) mode of peptide antigen delivery (surface displayed or internalized peptide) affects cross-presentation efficiency and the robustness of antigen-specific T cell expansion.

12.09.2025 14:22 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Immunization with peptide encapsulated within synthetic spores activates T cell responses and reduces tumor growth | mBio Effective delivery of antigens to the immune system is essential for activating the adaptive immune system. Synthetic Spore Husk-Encased Lipids (SSHELs) are synthetic bacterial spore-like particles, w...

Immunization with peptides can elicit antigen-specific T cell responses, but they're not widely used because they are poorly immunogenic and are rapidly cleared. Domenico D'Atri solves this by using our "SSHEL" platform (synthetic bacterial spores) .
journals.asm.org/doi/10.1128/...

12.09.2025 14:19 β€” πŸ‘ 14    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0
ASM Launches New Food Microbiology Journal ASM is launching ASM Food Microbiology, a new journal dedicated to advancing research on microbial safety, fermentation, spoilage and biotechnological innovations in food systems.

asm.org/press-releas...

11.09.2025 20:37 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Post image

Super cool Pseudomonas-Bacillus interaction paper in @natmicrobiol.nature.com from Yun Chen
with @gabrieleberg.bsky.social

Phenazines shape Gram+ abundance & influence Bacillus cell biology

Phenazines contribute to microbiome dynamics by targeting topoisomerase IV
www.nature.com/articles/s41...

11.09.2025 14:04 β€” πŸ‘ 33    πŸ” 14    πŸ’¬ 1    πŸ“Œ 1
Preview
Triple-Drug Combination for Cystic Fibrosis Wins Lasker Award JesΓΊs (Tito) GonzΓ‘lez, Paul Negulescu, and Michael Welsh received the 2025 Lasker Clinical Medical Research Award for the development of a life-saving cystic fibrosis treatment.

Fundamental science producing life-saving treatment

www.the-scientist.com/triple-drug-...

11.09.2025 16:15 β€” πŸ‘ 33    πŸ” 12    πŸ’¬ 0    πŸ“Œ 1
Preview
Translational coupling of neighboring genes in prokaryotes | Journal of Bacteriology Prokaryotic genes are arranged in operons, with functionally related genes often located adjacent to one another (1). There are several ways in which the operonic organization of genes facilitates the...

Check out our new paper: a review of translational coupling, the phenomenon where translation of one prokaryotic gene can promote translation of the gene downstream. We cover the history, and delve into the mechanism, which is still not fully understood. journals.asm.org/doi/10.1128/...

11.09.2025 16:45 β€” πŸ‘ 24    πŸ” 14    πŸ’¬ 0    πŸ“Œ 0
Preview
The endoribonuclease Rae1 from Bacillus subtilis cleaves mRNA upstream of stalled ribosomes Abstract. The ribosome-associated endoribonuclease 1 (Rae1) cleaves messengerΒ RNAs (mRNAs) in a translation-dependent manner. Here, we identify a new Rae1

The endoribonuclease Rae1 from Bacillus subtilis cleaves mRNA upstream of stalled ribosomes - academic.oup.com/nar/article/...

09.09.2025 10:39 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

@ramamurthilab is following 20 prominent accounts