Jutras Lab

The mass range of tandem mass spectra can be categorized into three main regions. For glycopeptides, the lower mass range contains mainly oxonium ions, the middle range contains mainly peptide fragments, and the high range contains charge-reduced fragments. All regions contain valuable fragment ion information, but they can only be simultaneously accessed by breaking the 5–10–15 rule.

MS/MS scan range can be an afterthought that doesn't receive attention in method design, but improper settings can affect experimental outcomes. This is especially true in glycoproteomics.

A #glycotime thread about a new #JASMS paper on this idea from @riley-research.bsky.social

1/10

Possibly… stay tuned 😉

Study reveals potential Lyme arthritis pathogenesis, treatment The chemical structure of the Borrelia burgdorferi cell wall may dictate the frequency and severity of Lyme arthritis, a finding that could have implications for future treatment, according to data pu...

New research from @jutraslab.bsky.social supported by #BAL highlights mechanism behind #Lymearthritis and points toward new treatment approaches. Learn more ⤵️
#LymeDisease #TickBorneDiseaseResearch

If asked, I would have corrected, but oh well. I didn’t even overlap with Sean. Mike for maybe just a month or two.

Josh Allen, Lamar Jackson, Baker Mayfield, Saquon Barkley. All exceptional, immediately, or in time. But, Sam Donald was drafted early in that class and was largely considered a bust. Maturity, patience, and perseverance drove Sam. Don’t love the Seahawks, but love the grit and determination. 👍 Sam!

Hey alpha aficionados - it's almost time for CauloCon 2026! This free, virtual meeting will feature talks from @brunlabcaulo.bsky.social @thanbichlerlab.bsky.social and @lamasonlab.bsky.social with opps for trainee talks. Register using the link below. 👇

a close up of a man 's face with a joker face paint ALT: a close up of a man 's face with a joker face paint

It’s batshit that study sections that didn’t meet in Nov (that were originally supposed to meet after gov re-opened anyway) were postponed 2+ months.

It’s flat out stupid to reschedule them for 2 days AFTER the CR was set to expire! Did they seriously think ‘nah, couldn’t happen again?!?!?’ 😡🤬😡

Many thanks to our collaborators Carmen Booth @yaleu.bsky.social @wolfzueckert.bsky.social for helping this one across the finish line! 👍

Peptidoglycan architecture dictates protein interactions, tissue tropism, and arthritis in the Lyme disease spirochete Borrelia burgdorferi Author summary Many of the pathogenic mechanisms by which Borrelia burgdorferi causes disease involve cell envelope interactions with host components. To further elucidate the role of peptidoglycan in...

Check out our exciting new paper out now in @plos.org where Dr Ahmad manipulated #peptidoglycan chemistry to understand Lyme disease and arthritis 👇👏
#Microsky
#glycotime

journals.plos.org/plospathogen...

The new vision from the National Institute of Allergy and Infectious Diseases (NIAID) - Nature Medicine Preparing for tomorrow’s threats by enhancing our ability to help patients today.

Pure malarkey that NIH director Jay’s first action item was to make all science open access then publishes his NIAID vision behind a paywall 🤣😆🤣

www.nature.com/articles/s41...

It’s more than comical that this article is behind a paywall, despite the new NIH guidelines

We are hiring! If you are a hardcore single molecule biophysicist specializing in fluorescence imaging, check it out here: apply.interfolio.com/179992

A small periplasmic protein governs broad physiological adaptations in Vibrio cholerae via regulation of the DbfRS two-component system - Nature Communications A two-component system, DbfRS, regulates biofilm formation in Vibrio cholerae. Here, Nguyen et al. identify a small periplasmic protein that controls the activity of the system’s receptor, and show th...

Thrilled to share that my first-author paper is now published in Nature Communications! 🎉 Huge thanks to my PI, Dr. Drew Bridges (@bridgesbio.bsky.social), my collaborators, and all the incredible lab members for their support throughout this project

www.nature.com/articles/s41...

Many thanks to @natmed.nature.com for highlighting some of our recent work on Lyme disease in their 'news' section. Important and timely piece 👇
#MicroSky

www.nature.com/articles/d41...

New article highlighting a few of the advances in Lyme disease research. Shout out to @jutraslab.bsky.social for their work! A lot of good research is happening in Lyme - excited for 2026! www.nature.com/articles/d41...

Fluorescence increases over time in mother cells due to aggregates.

How does E. coli age? According to this #mBio study, the the decisive factor driving growth decline in E. coli is not the presence of protein aggregates, but the fraction of the intracellular space they occupy. Learn more: asm.social/2KZ

manuscript accepted! Thankful the editorial crew pushed this across the finish line before the end of the year.

Standby for details on our findings

What is better than one? Two connected papers!

#NewResearch

S protein of Streptococcus pneumoniae activates PBP1a and coordinates with a wider GpsB-associated multi-protein complex to regulate peptidoglycan remodelling and cell division.

#MicroSky 🦠

www.nature.com/articles/s41...

I like that journals publish the timeline of events on the editorial side of a manuscript. BUT, they should also have to state how long they sit in limbo for transparency purposes. Like when simple text revisions are under re-review for 8 weeks and counting 🤨

Just got word that we are a go for the Bacterial Cell Biology and Development GRS and GRC at Southern New Hampshire University!

GRS will be on June 5-6, 2027

GRC will be from June 6-11, 2027

Block off your calendars Prokaryotic Cell Biologists!

More details to come! Please repost!

🚨The Yap Lab at Northwestern Univ is looking to fill 2 postdoc positions in 2026 to study aspects of Staphylococcus aureus antibiotic resistance and RNA synthesis-degradation. Please contact Frances Yap at frances.yap@northwestern.edu for details. sites.northwestern.edu/yaplab/. Pls repost #Microsky

No, It’s Not “Just a Meat Allergy”: The Truth About Alpha-gal Syndrome A 47-year-old pilot’s death after eating a hamburger reveals critical gaps in our understanding

Sharing this article that I wrote with my husband, @jutraslab.bsky.social for @unbiasedscipod.bsky.social. Last week researchers reported what appears to be the first clearly documented fatality from alpha‑gal syndrome.

#Scicomm #tickbornediseases #alphagalsyndrome

Oh, that’s wild! Light sensitivity is possible and something I must look into, but another thought is surface temp created by the light. Blue would create more thermal energy than white. Most tick receptors are temp and gas (CO2) responsive. Active after being frozen is another matter though…

I recognize that hypostome anywhere; beautiful image. Thanks!

Excited to see the light sheet images!!! 👀

Protecting Maternal Health and IVF A Personal Journey Through the Politics and Science of Reproductive Healthcare

I’m biased, and a bit teary eyed, but this article is outstanding and a testament to my beautiful wife’s
(@krosejutras.bsky.social)
courage, resolve, care for others, and exceptional writing abilities ❤️👇

theunbiasedscipod.substack.com/p/protecting...

@bstevensonlab.bsky.social
#microsky

👇👇👇 come to #mmpc2026 for the science, stay for the Minnesota Microbiology shirts (iykyk)

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