Ishmail Abdus-Saboor's Avatar

Ishmail Abdus-Saboor

@ishmailsaboor.bsky.social

Associate Prof | Columbia Biology & Zuckerman Institute Freeman Hrabowski Scholar | HHMI We study how the skin-brain axis drives somatosensory behaviors https://www.abdus-saboorlab.com/

3,156 Followers  |  484 Following  |  184 Posts  |  Joined: 22.11.2024  |  2.3233

Latest posts by ishmailsaboor.bsky.social on Bluesky

Attention, Attention, Early career investigators in Neuroscience: this is a great funding opportunity and a terrific community of scientists to join: deadline for application is February 25, 2026 πŸ§ πŸ§¬πŸ”¬πŸ§ͺ

06.10.2025 15:38 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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Darleane Hoffman, Innovator in Nuclear Chemistry, Dies at 98 Hailed as one of the 50 most important women in science, she found ways to study rare radioactive isotopes and advanced the understanding of nuclear fission.

Darleane Hoffman, a trailblazing nuclear chemist who was hailed by Discover magazine as one of the 50 most important women in science and whose research confirmed the existence of several elusive superheavy radioactive elements, died last month. She was 98.

05.10.2025 22:10 β€” πŸ‘ 313    πŸ” 69    πŸ’¬ 6    πŸ“Œ 5
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FlyVISTA, an integrated machine learning platform for deep phenotyping of sleep in Drosophila A machine learning platform identifies and characterizes the dynamics of microbehaviors during fly sleep.

I am proud to share that our work of 4+ years has finally been published. We wondered if there are distinct behaviors that mark sleep in πŸͺ°, where sleep has been defined as prolonged immobility.
πŸ”— www.science.org/doi/10.1126/...

08.04.2025 17:12 β€” πŸ‘ 34    πŸ” 13    πŸ’¬ 2    πŸ“Œ 2
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Enhanced PIEZO1 function contributes to the pathogenesis of sickle cell disease | PNAS Sickle cell disease (SCD), an inherited blood disorder caused by a mutation in the β-globin gene, is characterized by sickle erythrocytes that are ...

Our new PNAS paper "Enhanced PIEZO1 function contributes to the pathogenesis of sickle cell disease" is out: www.pnas.org/doi/10.1073/... 1/3

03.10.2025 16:53 β€” πŸ‘ 37    πŸ” 13    πŸ’¬ 2    πŸ“Œ 2

Congrats! I remember this project from my Penn Bio days.

04.10.2025 16:52 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
"… Goodall’s … is a story of genuine scientific curiosity, determination, and respect for
nature and humanity …" H. Holden Thorp, Editor-in-chief, Science journals

"… Goodall’s … is a story of genuine scientific curiosity, determination, and respect for nature and humanity …" H. Holden Thorp, Editor-in-chief, Science journals

Jane Goodall has died at the age of 91.

In 2020, Goodall spoke with Science Editor-in-Chief H. Holden Thorp for a #ScienceEditorial reflecting on the 60th anniversary of her arrival in Gombe to study wild chimpanzees. Read more: https://scim.ag/472Chb8

01.10.2025 19:13 β€” πŸ‘ 174    πŸ” 47    πŸ’¬ 4    πŸ“Œ 5
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1/ Starting next year, @hhmi.org will require all authors to share their research as preprints under a CC BY 4.0 license as part of its new Immediate Access to Research policy.
buff.ly/NrHlEKD

26.09.2025 12:11 β€” πŸ‘ 27    πŸ” 13    πŸ’¬ 1    πŸ“Œ 1

Big wow! Wonderful listen on my commute home. My 2 cents is that what @antihebbiann.bsky.social is talking about here (biological mechanisms for computation that interface with brain activity but go beyond it, like hormones) is the next big impactful thing, and she's among those leading the way 🀩.

24.09.2025 22:22 β€” πŸ‘ 24    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

love this pic and the people in it!

25.09.2025 23:33 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Very excited and proud to share my postdoctoral research with @neurrriot.bsky.social looking at the context-specific encoding of social behavior πŸ’ƒπŸ•Ί in hormone-sensitive, large-scale brain networks in mice!

www.biorxiv.org/content/10.1...

#neuroskyence #compneurosky πŸ§ͺ
1/12

25.09.2025 16:45 β€” πŸ‘ 180    πŸ” 46    πŸ’¬ 8    πŸ“Œ 9
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Excited to share this new work from the lab, in collaboration with @jtuscher.bsky.social & Rob Sorge! Here, we used single cell transcriptional profiling to define molecular adaptations induced by chronic pain and opioid experience, which often occur in conjunction.

www.biorxiv.org/content/10.1...

23.09.2025 18:27 β€” πŸ‘ 53    πŸ” 18    πŸ’¬ 4    πŸ“Œ 2

What a great retreat! Thanks to the entire UAB neuroscience community for contributing their science, and to @ishmailsaboor.bsky.social for an awesome keynote lecture!

22.09.2025 23:15 β€” πŸ‘ 14    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Ed Kravitz passed away yesterday.
He was a remarkable scientist and mentor- brilliant, curious, creative, and kind. I am grateful to have learned from him. His legacy will endure through his science and through the many people he inspired.

We will miss you, Ed.

22.09.2025 18:29 β€” πŸ‘ 57    πŸ” 22    πŸ’¬ 6    πŸ“Œ 2
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

Tenure-track Assistant Professor in Computational Ecology and/or Evolution @columbiauniversity.bsky.social.
Deadline to apply September 30.
Reach out if you have questions.

apply.interfolio.com/172496

20.09.2025 15:20 β€” πŸ‘ 32    πŸ” 46    πŸ’¬ 0    πŸ“Œ 0
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So proud of Jess Jones, an HHMI Gilliam Fellow, for defending her PhD today in @tuthill.bsky.social's lab! Jess was one of my lab's 1st hires in 2018. She was also 1st author of one of our first papers: elifesciences.org/articles/57258. I wouldn’t be where I am today without her contributions.

19.09.2025 21:56 β€” πŸ‘ 49    πŸ” 5    πŸ’¬ 2    πŸ“Œ 1

Very cool. A new mechanism found an ants to ensure the one-receptor-one olfactory neuron rule.

19.09.2025 15:37 β€” πŸ‘ 9    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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PIEZO channels link mechanical forces to uterine contractions in parturition Mechanical forces are extensively involved in pregnancy and parturition, but their precise roles and mechanisms remain poorly understood. Here, we identify mechanically activated ion channels PIEZO1 a...

New preprint alert! The uterus expands ~500-fold in pregnancy, yet we know little about how pressures are sensed. Led by @yunxiao-dr.bsky.social, we show PIEZOs are required for contractions and birth in mice, with dual roles of PIEZO1 in muscle and PIEZO2 in neurons
www.biorxiv.org/content/10.1...

18.09.2025 15:23 β€” πŸ‘ 126    πŸ” 41    πŸ’¬ 1    πŸ“Œ 1

fellow introvert here feels your pain

17.09.2025 20:06 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

cant wait!

16.09.2025 19:51 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

One of my favorite events that we @uabneuro.bsky.social host each year, and excited to have @ishmailsaboor.bsky.social here for the keynote!

16.09.2025 17:36 β€” πŸ‘ 9    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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Prefrontal Network Mechanisms of Psychiatric Deep Brain Stimulation Deep brain stimulation (DBS) is an emerging treatment for otherwise treatment-refractory psychiatric disorders. It can produce remarkable clinical results in expert hands, but has not fared as well in...

Prefrontal Network Mechanisms of Psychiatric Deep Brain Stimulation
www.jneurosci.org/content/45/3...
#neuroscience

15.09.2025 11:34 β€” πŸ‘ 20    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

Congratulations to you both! Go HBCUs!

14.09.2025 00:13 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

And yes, I should probably listen to the talk before asking questions πŸ€¦πŸΎβ€β™‚οΈ

13.09.2025 13:12 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

@earlkmiller.bsky.social do you believe this mixed selectivity is a feature of higher brain areas, or a general principle of neurons, like even primary neurons of sensory systems where its clear that they prefer given stimuli?

13.09.2025 13:11 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Deeply enjoyed reading this paper from Lindsey Salay, Doris Tsao, and David Anderson. Discovery of a neural circuit that integrates social touch and sexual drive for proper timing of mating behaviors.

12.09.2025 22:18 β€” πŸ‘ 13    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Major Medical Prizes Given to Cell Biology and Cystic Fibrosis Pioneers

Major Medical Prizes Given to Cell Biology and Cystic Fibrosis Pioneers www.nytimes.com/2025/09/11/h...

12.09.2025 00:45 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks @nicolecrust.bsky.social! Hanging out and talking about the past and future of neuroscience with you was also a highlight of my week. And these kind words you signed in my book were also memorable:

11.09.2025 23:32 β€” πŸ‘ 12    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Changes in cell type composition, including cell expansions, cell losses, and novel cell gains, are associated with the evolution of specific behaviors.
Figure credit: Matteo Farinella.

Changes in cell type composition, including cell expansions, cell losses, and novel cell gains, are associated with the evolution of specific behaviors. Figure credit: Matteo Farinella.

New review on how changes in cell type composition in and outside the brain contribute to the evolution of behavior. πŸ§ͺ

authors.elsevier.com/a/1lihM,LqAZ...

08.09.2025 15:41 β€” πŸ‘ 45    πŸ” 21    πŸ’¬ 2    πŸ“Œ 0

mind blowing! congrats @mishaahrens.bsky.social and team

08.09.2025 17:44 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87

David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87 www.nytimes.com/2025/09/07/s...

07.09.2025 21:20 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

@ishmailsaboor is following 20 prominent accounts