Maria GóRNA

Our new preprint is out!
We describe the unusual wacky enzyme used by trypanosomes to initiate mRNA degradation😉
Funded DE/CZ/PL WEAVE-UNISONO @ncn.gov.pl
👉The trypanosome mRNA decapping enzyme ALPH1 prefers caps without m7G methylation and produces diphosphate-RNA doi.org/10.64898/202...

List otwarty do Prezydenta RP, Marszałka Sejmu RP, Marszałka Senatu RP,  Prezesa Rady Ministrów oraz Wiceprezesów Rady Ministrów w sprawie finansowania nauki, w tym zwłaszcza Narodowego Centrum Nauki Szanowni Państwo, W niniejszej petycji prezentujemy List otwarty, który będzie wysłany do Kancelarii Prezydenta, Marszałków Sejmu i Senatu, Prezesa Rady Ministr&oacut...

Please consider signing a petition to increase the spending on science in Poland / List otwarty w sprawie finansowania nauki, w tym @ncn.gov.pl www.petycjeonline.com/list_otwarty...

FEBS Press Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA-binding prope...

Now out in FEBS Journal - the RNA binding properties of human FASTK, a regulator of mitochondrial metabolism and a potential target for autoimmune diseases therapies! Congrats to Daria & mito team Dawid Mikołaj 🎉
big thank you @ncn.gov.pl #NCNtoTlen doi.org/10.1111/febs...

Targeted protein degradation in Escherichia coli using CLIPPERs | EMBO reports imageimageCLIPPERs are new PROTAC-like peptide tools for targeted protein degradation in bacteria. CLIPPER peptides directly recruit the ClpXP protease to induce the degradation of an unmodified, degr...

Fantastic work by Matylda Izert pioneering Targeted Protein Degradation in Escherichia coli using a PROTAC-like approach!🎉 www.embopress.org/doi/full/10....
Could the future of antibiotics be #TPD?💊🧫
Thanks to FIRST TEAM FNP funding

There's a typo - of course the Master's diploma should be obtained by Sept 2025 for a start in Oct 2025😅 if a Master's has already been obtained, an earlier start is possible too😊

We're looking for a *PhD student* to join the FunHitDisco project! 😍
We offer work in a European consortium (SE/PL/NL/IT) dedicated to antifungal drug discovery! 🧫 💊 If you love proteins and structural biology, come join us! 🤗
#hiring #PhDoffer #PhDjob #PhDstudentship
gorna.uw.edu.pl/en/jobs

New year, new paper from my group! Ribosomes translocation into the spore of Bacillus subtilis is highly organised and requires peptidoglycan rearrangements
Funded by @FNP_org_pl @EMBO_YIP performed at @IBBPAS #subtiwiki
www.nature.com/articles/s41...

forgot to share our first lab biochemis-tree!
and the new lab mascot needed for all the cases of Murphy's law😉hopefully we can take them in stride next year❤️‍🔥

Naukowcy w Polsce funkcjonują w tej samej, opowiadanej ciągle od nowa historii. W której wszyscy znają diagnozę i recepty, ale zmieniają się tylko drobiazgi.
Tak to widzę.
Analiza stanu nauki w Polsce poleca się do czytania.

wyborcza.pl/magazyn/7,12...

We have been granted our first patent on the method of mRNA enrichment for sequencing or diagnostics. If you're interested in pppRNA or cap 0 RNA, we're happy to help!

Cap 0 example: IFIT1 replaces eIF4E for yeast and will work for fungi, plants and many lower eukaryotes🦠🍄🌱
doi.org/10.1093/nar/...

Thrilled to announce we got funded in the ERA-NET JPIAMR call!🎉https://jpiamr.eu/projects/funhitdisco/
We joined forces with colleagues from SE, NL, IT to work on new antifungal drugs!🍄🧫🧪💊💪 gorna.uw.edu.pl/en/news/jpi-... Thank you NCN for funding the PL part of the project #NCNtoTlen

I don't get the Jałta reference, nor care about aspic jelly, but I'm ticked off by association of Poland with Arctic weather - many seem to think we have polar bears on the streets or something while the weather is more or less the same as in Germany🤷‍♀️

Haha very fitting also for the funding situation in Poland

Podkast 111. Agata Starosta: Jesteśmy narzędziem w rękach bakterii Dlaczego warto żyć z nimi w komitywie? Z każdym rokiem odpowiedź na to pytanie staje się coraz bogatsza w znaczenia – opowiada dr hab. Agata Starosta, badaczka tych organizmów, biolożka molekularna, p...

Rozmowa o bakteriach, o tym czym zajmujemy się u mnie w laboratorium. Świetny prowadzący Karol Jalochowski. Polityka/Pulsar www.projektpulsar.pl/zdrowie/2278...

Fellow #RNA lovers, please repost 🙏: 2 ERC-funded Post-doc positions are available in our lab to investigate #RNA structural ensemble and their dynamics in living cells. Application link: t.co/pYJ3H3j705

I was playing around trying to make a nice "hello world" image for bsky debut💃 I don't quite know how I ended up with this one, but hey it makes sense, each one has a lamp to bask under😹 so here is "structural biology group working on antifungal drugs" by Copilot 😅 plus ofc 🐈‍⬛️🐈 make everything better