Noelle Held's Avatar

Noelle Held

@proteocean.bsky.social

proteomics, cellular decision-making, and biogeochemical cycles. assistant professor of marine & environmental biology @ USC. Also a yoga teacher. Your best is enough.

412 Followers  |  133 Following  |  22 Posts  |  Joined: 04.09.2023  |  1.9851

Latest posts by proteocean.bsky.social on Bluesky

Nutrient Co-limitation of Marine Microbes: Exploring Cellular to Ecosystem-Level Effects Nutrient availability limits microbial growth in marine ecosystems globally. Accumulating evidence has highlighted the prevalence of nutrient co-limitation, whereby two or more nutrients restrict mari...

๐ŸŒŠCurious how multi-nutrient scarcity impacts marine microbes๐Ÿฆ ? Excited to announce our #OSM26 session, Glasgow Feb 22-27! Join us in bridging cell biology, modelling & oceanography! tinyurl.com/zzt5s9su @exetermarine.bsky.social @thembauk.bsky.social @proteocean.bsky.social @cmarkmoore.bsky.social

31.07.2025 08:34 โ€” ๐Ÿ‘ 9    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Assistant Director of the Center for Proteomics Discovery (Research Program Administrator) The USC Dana and David Dornsife College of Letters, Arts and Sciences is seeking a Research Program Administrator (non-Clinical) and Assistant Director of the USC Center for Proteomics Discovery. This...

I am hiring a research/technical specialist/manager to help us make the most out of new LC-MS instrumentation at USC! Please share the word and write me for more details. usc.wd5.myworkdayjobs.com/en-US/Extern...

05.06.2025 16:43 โ€” ๐Ÿ‘ 4    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Part 1: Zonal gradients in phosphorus and nitrogen acquisition and stress revealed by metaproteomes of Prochlorococcus and Synechococcus Abstract. Ocean warming alongside changes to the natural and anthropogenic supply of key nutrient resources such as nitrogen, phosphorus and trace metals is predicted to alter the magnitude and stoich...

Super glad to share two new papers about how nutrient gradients impact alkaline phosphatase in the ocean. This was "that project" which followed from PhD to Postdoc to Assist. Prof, motivated by awesome collaborators! egusphere.copernicus.org/preprints/20... egusphere.copernicus.org/preprints/20...

04.03.2025 21:57 โ€” ๐Ÿ‘ 6    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ”ฅThanks, Don Beyer and staff!

07.02.2025 21:13 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐Ÿšจ The Trump administration is attempting to seize power beyond what the Constitution allowsโ€”giving Elon Musk, an unelected billionaire, unchecked influence.

As a federal scientist, expert, or civil servant, you have rights. Donโ€™t let them bully you.

These resources can help: act.ucsusa.org/4hqSJoz

06.02.2025 16:11 โ€” ๐Ÿ‘ 274    ๐Ÿ” 141    ๐Ÿ’ฌ 7    ๐Ÿ“Œ 10
A slightly wet dog standing on Santa Monica pier

A slightly wet dog standing on Santa Monica pier

Weโ€™ve been sampling the Santa Monica bay since Jan for changes in the marine microbiome due to runoff of debris from the fires. Today I brought a sampling buddy along. We should teach him to pull the cart.

06.02.2025 15:23 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Reiterating my call to fellow federally-funded scientists: Call your reps, tell them how this hurts science and everything good that comes from science

(Also non-scientists, and scientists without federal funding! But the more of us who can directly speak to the impacts of these freezes the better)

28.01.2025 00:26 โ€” ๐Ÿ‘ 252    ๐Ÿ” 161    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 9
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MICO/Brisbin lab is hosting Making Waves REUs this summer! Please share with your favorite undergrads! Are you an undergrad excited about oceanography? Apply or reach out with questions! #reu #microbialsky

16.01.2025 17:19 โ€” ๐Ÿ‘ 0    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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I really wanted a long distance penpal as a kid - so a fun upside of the transientness of early career academia is that I am now sending new years cards to friends all over the world - just posted to Germany, Australia, Switzerland, the UK, Italy, Russia, France, Canada, and Chile!

01.01.2025 21:35 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Stable isotope fingerprinting can directly link intestinal microorganisms with their carbon source and captures diet-induced substrate switching in vivo Diet has strong impacts on the composition and function of the gut microbiota with implications for host health. Therefore, it is critical to identify the dietary components that support growth of spe...

We showed that #metaproteomics based "Stable isotope fingerprinting can directly link intestinal microorganisms with their carbon source and captures diet-induced substrate switching in vivo"
www.biorxiv.org/content/10.1...
Great work by Angie Mordant and Alfredo Blakeley-Ruiz @alfredob.bsky.social

27.12.2024 17:18 โ€” ๐Ÿ‘ 20    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Meet the 2025 Wrigley Institute Graduate Fellows - Wrigley Institute for Environment and Sustainability Creating a more sustainable and environmentally just future for our planet and all who live on it

More good news to round out the year, Proteocean Lab PhD student Mia Franks is a Wrigley Institute Graduate Fellow! She joins a very cool, very diverse group of student researchers and will quantify nutrient colimitation in the San Pedro Channel. Yay Mia! dornsife.usc.edu/wrigley/2024...

20.12.2024 20:41 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

This work is transforming my own approach to nutrient incubations and omics data - how can we design these to be more quantitative?

18.12.2024 19:29 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

What does it really mean to be in nutrient colimitation? We demonstrate a distinct growth phenotype and that (co)limitation can (and should!) be quantified. The result of many late afternoon chats with @michaelmanhart.bsky.social. Let us know what you think! www.pnas.org/doi/10.1073/pnas.2400304121

18.12.2024 19:27 โ€” ๐Ÿ‘ 12    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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5 years ago toda I defended my thesis (thanks for the reminder @maksaito.bsky.social!) 1 year ago today was my first day in LA. Time flies! The dog is not impressed.

06.12.2024 20:39 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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We're still looking for a postdoc in metabolic modeling and culture-based validation. If it sounds like you, reach out to discuss! www.isme-microbes.org/jobs/postdoc...

30.04.2024 18:29 โ€” ๐Ÿ‘ 2    ๐Ÿ” 13    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

And it takes me two weeks to install a python library.

23.04.2024 03:20 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Starting my rejections garden. Adding a plant for every no. Going strong at 4 months in - Iโ€™ll have an epic office garden in no time. Anyway, even though it feels crummy, there can be growth. ๐ŸŒฟ

17.04.2024 23:58 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Has anyone had experience with a preprint being published, along with a bunch of AI text and a fake image, on one of those NFT sites? It grosses me out, not sure of legality??

09.04.2024 15:44 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Are microbes colimited by multiple resources?

Microbes need many different resources, but do some of these resources simultaneously COLIMIT growth? @proteocean.bsky.social and I provide a new review of this concept, a summary of evidence that colimitation occurs in natural environments, and its causes/consequences. doi.org/10.32942/X2S... 1/6

05.03.2024 04:52 โ€” ๐Ÿ‘ 6    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Time for another new lab poll - What ultra pure water system does your lab have and do you like it?

01.03.2024 02:46 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Second growth on HEPES and basically all buffers.

09.02.2024 02:10 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Cool opportunity if youโ€™d like to postdoc at USC and work across departments in sustainability! Awesomely, the fellowship includes targeted career development! Weโ€™re ramping up relevant themes in the proteocean lab, contact me! www.ssf.usc.edu

09.01.2024 19:58 โ€” ๐Ÿ‘ 1    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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In times like these the Oceanography training really pays off - I basically got a PhD in shipping weird stuff halfway across the world.

25.11.2023 13:17 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

First instance of helpless panic waiting for a grant to route through approvals, minutes before agency deadline: โœ… Also, first instance of grant manager angel saving the day: โœ… What right of passage is next?

16.11.2023 09:04 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Our lab is recruiting a Ph.D. student for fall 2024! If you are interested in the ecology, evolution, and systems biology of microbial communities (especially using theory and modeling), please apply by November 1 according to the attached ad and link
qevomicrolab.org/wp-content/u...

03.10.2023 23:57 โ€” ๐Ÿ‘ 11    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Letโ€™s talk about nutrient (co)limitation as a quantitative property of microbial populations and communities! Plus, we show that colimitation for two essential nutrients is accessible in laboratory conditions. Preprint here: www.biorxiv.org/content/10.1...

28.09.2023 07:06 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Iโ€™m working to find examples on my end, but if anyone would be willing to share a successful NIH K99 related to microbial ecology and/or evolution it would be much appreciated.

20.09.2023 15:13 โ€” ๐Ÿ‘ 0    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Though it is changing, one thing I love about proteomics is that small companies still have a powerful niche. I love these SPF plates and I love even more that I can order them with a quick email to a two-man operation in Ipswich (from what I can tell).

19.09.2023 13:11 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@mixotrophe.bsky.social @manuelkleiner.bsky.social thanks! I am mainly worried about one-off meetings with students/collaborators/small groups. Iโ€™ve never loved polling but I donโ€™t see a way around it.

17.09.2023 17:38 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

How do you schedule meetings and does your system work for you? #newPI

17.09.2023 12:11 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0

@proteocean is following 20 prominent accounts