Katrin Franke

Sleep spindles promote hippocampal network downregulation during sleep Sleep is thought to globally downregulate neuronal network activity and synaptic connections enhanced during prior wakefulness and, in parallel, to up…

@currentbiology.bsky.social
I am very happy to share our latest paper, just published in @currentbiology.bsky.social! In collaboration with Olga Garaschuk's lab, we used in vivo 2P calcium imaging to investigate the role of sleep spindles in the hippocampus. 🧠💤
www.sciencedirect.com/science/arti...

After 5 years of developing, a new preprint from the lab - introducing our workflow for comparative insect connectomics, aimed at democratizing connectomics. @erc.europa.eu @lundvision.bsky.social @biologylu.bsky.social Read it here: www.biorxiv.org/content/10.6...

a black and white dog is sitting on a couch with its tongue sticking out . ALT: a black and white dog is sitting on a couch with its tongue sticking out .

👁️The retina — strikingly conserved across vertebrates, but an oddity among bilaterians!

So how did it evolve?

With @mikebok.bsky.social, @neurofishh.bsky.social and @denilsson.bsky.social, we argue that retinal complexity may 𝑝𝑟𝑒𝑑𝑎𝑡𝑒 𝑡ℎ𝑒 𝑒𝑦𝑒 𝑖𝑡𝑠𝑒𝑙𝑓.

www.biorxiv.org/content/10.1...
1/n

Congrats George!

🚨 We're hiring: Research Coordinator for CRC Robust Vision
@unituebingen.bsky.social

Take a leading role in our DFG funded consortium in neuroscience, ML & CV

MSc/PhD + science mgmt. Apply by Mar 15 👇 join our team w/ @jakhmack.bsky.social @bethgelab.bsky.social

uni-tuebingen.de/en/universit...

I have been using Claude Code recently, and I’m now convinced that LLM coding agents can solve one of the biggest problems in neuroscience: technical debt.

Labs generate tons of low-quality code bc the incentive structure rewards short-term productivity over longer-term concerns like 1/

I’ve been using Spikeling in teaching and outreach for the past 4 years, and it’s been a really effective way to make neuroscience concepts more approachable and engaging.

Hands-on tools like this really help move neuroscience teaching forward 🧠⚡

Have a look 👇

For this new year, we are proud to announce the launch of Spikeling v3 !

Spikeling is an Open-Source neuroscience education platform that brings a patch-clamp-style electrophysiology workflow into the classroom.

#Neuroscience #OpenScience #OpenHardware #Education

Marine Biological Laboratory Explores Human Memory With AI and Virtual Reality The lab in Massachusetts is studying molecular mechanisms of human memory function powered by NVIDIA RTX GPUs, HP Z Workstations and virtual-reality technology.

Nice feature from NVIDIA on #syGlass at the MBL! Exciting to see AI, RTX GPUs, and VR coming together to explore massive 3D brain datasets, with high school students contributing to ongoing, cutting-edge neuroscience research.
@mblscience.bsky.social

blogs.nvidia.com/blog/mbl-hum...

Ever wanted to know how the visual system of a long distance migratory moth looks like? Then you'll find your answers in our new paper. Finally out, after about a decade of collecting data by a group af amazing co-authors. Find it here, open access: link.springer.com/article/10.1...

Lindsay Lab - Postdoc Position Artificial neural networks applied to psychology, neuroscience, and climate change

Spread the word: I'm looking to hire a postdoc to explore the concept of attention (as studied in psych/neuro, not the transformer mechanism) in large Vision-Language Models. More details here: lindsay-lab.github.io/2025/12/08/p...
#MLSky #neurojobs #compneuro

Thanks to the team:
@Jonathan Oesterle @thomaszen.bsky.social @fededagos.bsky.social @teuler.bsky.social @philipp.hertie.ai @katrinfranke.bsky.social @Timm Schubert @Zhijian Zhao @nadinedyszkant.bsky.social @Klaudia Szatko @Chenchen Cai @florentyna-d.bsky.social @tom-sk.bsky.social @Ryan Arlinghaus

📦Dataset: huggingface.co/datasets/eul...
💻Code: github.com/eulerlab/all...
🧠GCL Classifier: github.com/eulerlab/gcl...
🤖DataJoint Database: github.com/eulerlab/dji...

A large-scale dataset of functional mouse ganglion cell layer responses We present the All-GCL dataset, a large-scale resource of functional two-photon Ca2+-imaging recordings with rich meta-data information from more than 80,000 cells in the ganglion cell layer (GCL) of ...

We’re excited to share ALL-GCL: a large-scale dataset of 2P Ca²⁺ imaging from 80,000+ cells in the mouse retinal ganglion cell layer, collected over 9 years. Includes rich metadata, shared stimuli & cell-type assignments designed for type-specific analyses, modeling, and ML.

📄: tinyurl.com/ymn53frf

Why isn’t modern AI built around principles from cognitive science? First post in a series on cognitive science and AI

Why isn’t modern AI built around principles from cognitive science or neuroscience? Starting a substack (infinitefaculty.substack.com/p/why-isnt-m...) by writing down my thoughts on that question: as part of a first series of posts giving my current thoughts on the relation between these fields. 1/3

Schematic of how ER-EPG plasticity enables the bump of activity in EPGs to accurately track visual cues. As a fly makes a counter-clockwise turn (top to bottom) it will view visual cues (e.g. the sun) from a new angle and the EPG activity bump (red) will swing clockwise around the network by integrating self motion signals with these visual inputs. When the fly faces a different angle, distinct visual ER neurons are active. Plasticity forms a trough of weak synapses (large circles - strong synapses, small circles - weak synapses) that allow ER neurons with distinct visual tuning to move the EPG bump via disinhibition.

*First preprint from our lab* !!!!!
How does the brain learn to anchor its internal sense of direction to the outside world? 🧭
led by Mark Plitt @markplitt.bsky.social & Dan Turner-Evans, w/ Vivek Jayaraman:
“Octopamine instructs head direction plasticity” www.biorxiv.org/content/10.6...
Thread ⬇️

Hierarchical organization of mechano-nociceptive pathways revealed by activity labeling Noxious mechanical stimuli give rise to distinct percepts, from sharp cutaneous pain to diffuse visceral discomfort, yet the nociceptor ensembles that underlie these differences remain poorly defined....

Not all pain is created equal: stepping on a nail feels different from a stomachache. We know there are many nociceptor types, but a key question remains: how is mechanical pain encoded across the body by those sensory neurons? Our new work helps answer this. 1/8
www.biorxiv.org/content/10.6...

We're thrilled to introduce ATHENA: Automatically Tracking Hands Expertly with No Annotations – our open-source, Python-based toolbox for 3D markerless hand tracking!

Paper: www.biorxiv.org/content/10....

In this piece for @thetransmitter.bsky.social, I argue that ecological neuroscience should leverage generative video and interactive models to simulate the world from animals' perspectives.

The technological building blocks are almost here - we just need to align them for this application.

🧠🤖

🧠📢 New preprint alert

Large-scale ephys is exploding but spike sorting remains the computational bottleneck. A 2-hr, 6-probe Neuropixels 2.0 Quad Base session can take over a week to sort on a single machine. Here's a better solution. 🧵

#neuroskyence #compneurosky

Finally got the job ad—looking for 2 PhD students to start spring next year:

www.gao-unit.com/join-us/

If comp neuro, ML, and AI4Neuro is your thing, or you just nerd out over brain recordings, apply!

I'm at neurips. DM me here / on the conference app or email if you want to meet 🏖️🌮

🚀 Thrilled to be at #NeurIPS2025

🧠 Doing NeuroAI: using AI to understand the brain

🎤 Catch my Sunday talk at @neurreps.bsky.social on interpreting the neural code

Interested in the🔬Enigma Project at Stanford?

Working with @andreastolias.bsky.social & @naturecomputes.bsky.social enigmaproject.ai

#FluorescenceFriday

A sky of light within ✨
This is the ganglion cell layer of the avian retina. The nerve fiber layer lies beneath like a soft green current, carrying quiet signals forward.

Sometimes to see the universe with its beautiful scattered stars, one only has to look inside.

That image is from 1961 and an idealization. Here is an actual trajectory of fixational eye movements. The dots are 2 ms apart. If a midget ganglion cell, with single-cone receptive field, fires at 100 Hz, then every spike reports about a different cone. How can we ever read anything?

Perfect for someone who loves: ✨ Advanced imaging techniques ✨ Interdisciplinary science ✨ Understanding brain computation

Interested? Please send your application (CV, motivation letter) to ​​sinz@uni-goettingen.de

#neurosky #neuroskyence #Neuroscience #PostDoc #JobOpening

🔬 Exciting PostDoc Opportunity! 🐁🧠

We - the @sinzlab.bsky.social (sinzlab.org) and @trose-neuro.bsky.social (troselab.de) Labs - are seeking an experimental postdoc to work at @unibonn.bsky.social with cutting-edge miniature 2-photon microscopy and gaze tracking in freely behaving mice.

To study how animals understand the physical world (and the rules that govern its dynamics), @jinyao-y.bsky.social trains rats to play fetch with robots 🐀🤖🎾

To learn more, come to our poster Tuesday morning!
[Board W11] Rats learn and use intuitive physics knowledge to solve fetch tasks.
#SfN2025

AI and Neuroscience | IVADO

I’m looking for interns to join our lab for a project on foundation models in neuroscience.

Funded by @ivado.bsky.social and in collaboration with the IVADO regroupement 1 (AI and Neuroscience: ivado.ca/en/regroupem...).

Interested? See the details in the comments. (1/3)

🧠🤖

Rumor has it Mother Nature might be the best AI engineer🌱💡

Come see why at Brass Bear Brewing, Nov 13 @ 6pm. With Dr. Fatih Dinc, we’ll dive into how brains, bots, and biology compute with intelligence

🕳️🐇Into the Rabbit Hull – Part II

Continuing our interpretation of DINOv2, the second part of our study concerns the *geometry of concepts* and the synthesis of our findings toward a new representational *phenomenology*:

the Minkowski Representation Hypothesis