RED lab

David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87

Co-discoverer of reverse transcriptase at 32, Nobel Prize at 37, played a key role at the 1975 Asilomar comference.

What an amazing meeting I've just been at! ADHERE2, where Adhesion experts meet and discuss their excellent science, go for boat trip and jump to the water in the middle of the sea. Thank you so much Andreja Ambriović-Ristov, Ben Goult and Vassiliki Kostourou!

Looking forward to ADHERE3!

Regulatory feedback between VEGF and ERK pathways controls tip-cell expression during sea urchin skeletogenesis Summary: The skeletal elongation of the sea urchin embryo is driven by positive feedback between the VEGF and ERK pathways that control cell migration and gene expression at the skeletogenic tip cells...

✨ New paper in Development!
We found a positive feedback loop between VEGF and ERK signaling that controls tip-cell expression during sea urchin skeletal elongation — just like in vascular sprouts!

🔗 journals.biologists.com/dev/article/...

Possible role of microtubules in vesicular transport of matrix protein during sea urchin larval biomineralization Background Biomineralization is a vital biological process through which organisms produce mineralized structures such as shells, skeletons, and teeth. Microtubules are essential for biomineralizati...

Our new paper is out! 🎉
We show how microtubules may help traffic matrix proteins into the biomineralization compartment.
Congrats to the team for this beautiful work!
🔗 anatomypubs.onlinelibrary.wiley.com/doi/full/10....

Skeletogenic Expression of Integrin Alpha, Talin and Npnt Genes and Npnt Role in Sea Urchin Skeletogenesis Three integrin alpha genes and the cytoskeletal adaptor talin are enriched in sea urchin skeletogenic cells during early skeletogenesis. The extracellular matrix protein nephronectin (Npnt) is expres....

When Shanduo Chen joined my lab , he could barely speak English and had little experience with molecular biology. But he was determined, hardworking, had a critical mind and deep curiosity. He now produced this beautiful paper, published in JezB! So proud!

onlinelibrary.wiley.com/doi/10.1002/...