Charles Marshall

Graphic reads 'The Nottingham Consensus. Read the publication and policy brief: denpru-qmul.nihr.ac.uk/resources. Image of two speech bubbles and the DeNPRU-QM logo.

The Nottingham Consensus provides a policy roadmap to reduce dementia risk, the UK's leading cause of death. Recommendations include:

📢 Launch a targeted public health campaign to address key modifiable risk factors

💬 Adapt communication strategies to ensure relevance across diverse communities

The Nottingham consensus on dementia risk reduction policy: recommendations from a modified Delphi process Nature Reviews Neurology, Published online: 16 January 2026; doi:10.1038/s41582-025-01173-9Translation of evidence about dementia risk into effective public health policy is a challenge. In this Consensus Statement, Demnitz-King and colleagues present 56 policy recommendations for dementia prevention, providing policymakers with a foundation for designing and implementing evidence-based dementia prevention strategies, prioritizing clear communication, targeted intervention and sustained research investment.

New online! The Nottingham consensus on dementia risk reduction policy: recommendations from a modified Delphi process

New paper led by @denpru-qm.bsky.social brings together 40 dementia experts – including ARUK’s Policy team – to agree on key things decision makers need to do to help cut dementia risk. #denpruQM

The panel developed 56 recommendations across four domains:

📢 Public health messaging
👟 Individual-level interventions
🌍 Population-level interventions
📚 Research commissioning

Read our policy brief for a summary: tinyurl.com/5e2tn4u4

@charlesmarshall.bsky.social @hdemnitzking.bsky.social

Text reads: New publication. The Nottingham consensus on dementia risk reduction policy. Graphic shows three speech bubbles connected via arrows.

How can policy reduce dementia risk?

We convened a panel of experts to develop policy recommendations for dementia risk reduction, refining them through a modified-Delphi process.

The final result is the Nottingham consensus, published today in @natrevneurol.nature.com 👇

tinyurl.com/4rsz2yy6

The Nottingham consensus on dementia risk reduction policy: recommendations from a modified Delphi process - Nature Reviews Neurology Translation of evidence about dementia risk into effective public health policy is a challenge. In this Consensus Statement, Demnitz-King and colleagues present 56 policy recommendations for dementia ...

What should the Department of Health and Social Care be doing to improve the nation’s brain health?

@hdemnitzking.bsky.social and I brought UK experts together to produce a consensus roadmap for dementia risk reduction on behalf of @denpru-qm.bsky.social

www.nature.com/articles/s41...

A panel discussion with five speakers sat on chairs on a raised stage. Professor Claudia Cooper is holding the microphone and speaking.

Thank you @alzheimersresearchuk.org London Network Centre for inviting us to speak at your PPI event today.

We joined lived experience experts, researchers and clinicians to discuss putting people at the centre of dementia research and care.

@claudiacooper.bsky.social @charlesmarshall.bsky.social

Diagnostic and other biomarkers of dementia with Lewy bodies: from research to clinical settings Dementia with Lewy bodies is characterised clinically by visual hallucinations, fluctuating cognitive function, parkinsonism, and rapid eye movement s…

Thrilled to share our review on imaging and fluid biomarkers in dementia with Lewy bodies with @angelikaza.bsky.social and wonderful collaborators Brit Mollenhauer Louis CS Tan Michael Bartl and Nick Fox @uclqsion.bsky.social

www.sciencedirect.com/science/arti...

Evaluating the link between hearing loss and Alzheimer’s disease neuropathology: A systematic review and meta-analysis Hearing loss has been linked with cognitive decline and increased dementia risk. The neurobiological mechanisms underlying this relationship are not c…

✨ SHINY NEW PAPER ✨

Hearing loss is more strongly associated with tau burden than β-amyloid (Aβ) burden.

@charlesmarshall.bsky.social

www.sciencedirect.com/science/article/pii/S0197458025001162

Golnaz Atefi presenting DeNPRU-QM work at Alzheimer's Europe Conference in Bologna, October 2025

Great to see researcher Golnaz Atefi present 'Attitudes Toward Brain Health and Dementia Risk Reduction Among Minoritised Ethnic Communities in the UK' at #35AEC. Project led by Prof Naaheed Mukadam #denpruQM @claudiacooper.bsky.social @charlesmarshall.bsky.social @qmulpsychiatry.bsky.social

TWO @nihr.bsky.social Academic Clinical Fellowship opportunities are currently available to come and work with us @preventiveneur1.bsky.social

Get in touch to discuss, and if you need any persuasion, here’s what our team say about what it’s like to work here!

www.oriel.nhs.uk/Web/PermaLin...

The contribution of Apoliproprotein E genetic variation to dementia risk in British South Asians INTRODUCTION Understanding the genetic basis of dementia in diverse populations is essential to ensure that efforts to predict, prevent, and treat dementia are equitable. The strongest genetic risk fa...

🚨 New pre-print! 🚨

Dr. Avi Chandra and Ben Jacobs study dementia genetics in underrepresented populations. 🧬✨

In 51,000+ British South Asians, they show APOE influences dementia risk, underscoring the need for equitable care.

Read more: www.medrxiv.org/content/10.1...

🤩🤩

🎉 Recruitment for DIADEM is closed!

The DIADEM study is exploring if central hearing tests can help detect dementia.

Over 450 participants across 17 UK sites—huge thanks to all involved! 💙

Shoutout to DIADEM top recruiters Lauren Bishop & Dicky Lim, who’ve seen over 100 participants together! 🏆🎂

Harriet standing by a poster on dementia risk reduction policy at AAIC 2025 in Toronto

A lot of early interest in #denpruQM consensus on dementia risk reduction policy at #AAIC25 presented by our great post-doc @hdemnitzking.bsky.social with the project led by @charlesmarshall.bsky.social Paper available later this year. @qmulpsychiatry.bsky.social @claudiacooper.bsky.social

What does the public think about preventing dementia, MS & Parkinson’s? @denpru-qm.bsky.social has just released findings from our YouGov poll, surveying 1,700 people in England, to explore attitudes to neurological prevention: bit.ly/3TwiN7l

Evaluating the link between hearing loss and Alzheimer’s disease neuropathology: A systematic review and meta-analysis Hearing loss has been linked with cognitive decline and increased dementia risk. The neurobiological mechanisms underlying this relationship are not c…

🧠👂 Dr Avi Chandra’s latest research links hearing loss—especially central— to Alzheimer’s pathology including increased Aβ and tau burden.

❓ But what is the underpinning relationship between these factors?

Watch this space!🧬🧩

To read more ⬇️

www.sciencedirect.com/science/arti...

The front slide of a PowerPoint presentation. The text reads 'Reducing the risk of dementia: policy recommendations from a panel of experts'. Harriet Demnitz-King and Debs Smith.

Debs Smith and Harriet Demnitz-King presenting

Great to be at the @spindnetworkplus.bsky.social Science Festival 2025 today 🎪

@hdemnitzking.bsky.social (Early Career Researcher at #denpruQM) and Patient and Public Engagement Group member Debs Smith presented findings from our consensus workshop on public health policy for dementia prevention.

Causes and consequences of vascular dementia across the life course: Evidence from a UK Biobank phenome-wide and Mendelian randomization study Background Vascular dementia (VaD) is the second most common cause of dementia, yet its risk factors and biological mechanisms remain poorly understood. Objective To identify causes and consequences ...

Fabulous work by Phazha Bothongo!

2 years and several near mental breakdowns for us both in the making!

🧠 Causes and consequences of vascular dementia across the life course: Evidence from a UK Biobank phenome-wide and Mendelian randomization study 🧠

www.medrxiv.org/content/10.1...

Listen here➡️

Curious how divorce and widowhood affect the brain? 🧠

Take a deep dive into how these major life events may be linked to cognitive decline with Dr. Avi Chandra in the latest episode of ISTAART Voices.

🎙️ Listen now: alz.org/ISTAARTpodcast

💼 We're looking for a mixed methods Research Assistant to join our team from August.

📈 You'll work across a range of projects utilising quantitative & qualitative methods, which may include health economics.

⏰ Apply via our website by Tuesday 6th May: shorturl.at/NxSqe

Please share widely!

Research Assistant: Equitable health and social care Join NIHR DeNPRU-QM at Queen Mary as a Research Assistant to support dementia & neurodegeneration policy research. 18-month role starts after 6 Aug 2025.

Join NIHR DeNPRU-QM at Queen Mary as a Research Assistant to support dementia & neurodegeneration policy research. 18-month role, apply by 6th May @denpru-qm.bsky.social

www.dementiaresearcher.nihr.ac.uk/job/research...

Come and work with us! Excellent research and policy research experience in a supportive socially active team

📣 We're recruiting a mixed methods Postdoctoral Research Associate to join our team from August 2025 📣

You'll have a PhD (or near completion) & enjoy working with large data sets. Apply here:

shorturl.at/Z4SHk

@claudiacooper.bsky.social @qmulpsychiatry.bsky.social @dementiaresearcher.bsky.social

Please do think of joining us or pass this on to someone you know who might fancy it. I am, of course, rather biased but I think we are a lovely bunch, trying to help answer some really important questions. Always happy to chat to anyone who is interested!

Detecting early neurovascular dysfunction in Alzheimer’s Disease and Cerebral Amyloid Angiopathy (CAA) at University College London on FindAPhD.com PhD Project - Detecting early neurovascular dysfunction in Alzheimer’s Disease and Cerebral Amyloid Angiopathy (CAA) at University College London, listed on FindAPhD.com

Excited to share a new PhD studentship, using fMRI and MEG to detect early changes in Alzheimer's disease, fully funded for a UK student by @alzheimersresearchuk.org . Situated at UCL in Queen Square, London. Join us! tinyurl.com/nvmgroupphd

🚨Fantastic job opportunity for neurology trainees

Neurology Clinical Lecturer post in Dementia with us @qmuldementia.bsky.social now open to applications!

Please DM me for info and to discuss

www.oriel.nhs.uk/Web/PermaLin...

Early presentations of dementia in a diverse population INTRODUCTION Improved recognition of non-cognitive presentations of dementia could reduce inequalities in dementia diagnosis, particularly if sociocultural factors influence help-seeking for cogniti...

Early presentations of dementia in a diverse population alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

I think yes to both. We also need to look at combinations of features and consider the idea of automated dementia risk flags in primary care in the next phase.

New research, born out of community engagement work, shows that the symptoms people report prior to receiving a dementia diagnosis vary across ethnic groups.

www.qmul.ac.uk/media/news/2...

@qmulfmd.bsky.social @charlesmarshall.bsky.social @alzassociation.bsky.social @alzheimerssoc.bsky.social