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Charles Marshall

@charlesmarshall.bsky.social

Professor of Clinical Neurology. Clinical Director for Dementia for NHS London. Interested in dementia diagnosis, treatment and health inequalities

231 Followers  |  126 Following  |  7 Posts  |  Joined: 07.02.2024  |  2.2045

Latest posts by charlesmarshall.bsky.social on Bluesky

Golnaz Atefi presenting DeNPRU-QM work at Alzheimer's Europe Conference in Bologna, October 2025

Golnaz Atefi presenting DeNPRU-QM work at Alzheimer's Europe Conference in Bologna, October 2025

Great to see researcher Golnaz Atefi present 'Attitudes Toward Brain Health and Dementia Risk Reduction Among Minoritised Ethnic Communities in the UK' at #35AEC. Project led by Prof Naaheed Mukadam #denpruQM @claudiacooper.bsky.social @charlesmarshall.bsky.social @qmulpsychiatry.bsky.social

07.10.2025 04:50 β€” πŸ‘ 7    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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TWO @nihr.bsky.social Academic Clinical Fellowship opportunities are currently available to come and work with us @preventiveneur1.bsky.social

Get in touch to discuss, and if you need any persuasion, here’s what our team say about what it’s like to work here!

www.oriel.nhs.uk/Web/PermaLin...

02.10.2025 12:25 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The contribution of Apoliproprotein E genetic variation to dementia risk in British South Asians INTRODUCTION Understanding the genetic basis of dementia in diverse populations is essential to ensure that efforts to predict, prevent, and treat dementia are equitable. The strongest genetic risk fa...

🚨 New pre-print! 🚨

Dr. Avi Chandra and Ben Jacobs study dementia genetics in underrepresented populations. 🧬✨

In 51,000+ British South Asians, they show APOE influences dementia risk, underscoring the need for equitable care.

Read more: www.medrxiv.org/content/10.1...

19.09.2025 09:22 β€” πŸ‘ 1    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

🀩🀩

01.08.2025 13:10 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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πŸŽ‰ Recruitment for DIADEM is closed!

The DIADEM study is exploring if central hearing tests can help detect dementia.

Over 450 participants across 17 UK sitesβ€”huge thanks to all involved! πŸ’™

Shoutout to DIADEM top recruiters Lauren Bishop & Dicky Lim, who’ve seen over 100 participants together! πŸ†πŸŽ‚

01.08.2025 08:04 β€” πŸ‘ 9    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Harriet standing by a poster on dementia risk reduction policy at AAIC 2025 in Toronto

Harriet standing by a poster on dementia risk reduction policy at AAIC 2025 in Toronto

A lot of early interest in #denpruQM consensus on dementia risk reduction policy at #AAIC25 presented by our great post-doc @hdemnitzking.bsky.social with the project led by @charlesmarshall.bsky.social Paper available later this year. @qmulpsychiatry.bsky.social @claudiacooper.bsky.social

30.07.2025 13:31 β€” πŸ‘ 16    πŸ” 11    πŸ’¬ 0    πŸ“Œ 2
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What does the public think about preventing dementia, MS & Parkinson’s? @denpru-qm.bsky.social has just released findings from our YouGov poll, surveying 1,700 people in England, to explore attitudes to neurological prevention: bit.ly/3TwiN7l

09.07.2025 11:10 β€” πŸ‘ 8    πŸ” 6    πŸ’¬ 1    πŸ“Œ 1
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Evaluating the link between hearing loss and Alzheimer’s disease neuropathology: A systematic review and meta-analysis Hearing loss has been linked with cognitive decline and increased dementia risk. The neurobiological mechanisms underlying this relationship are not c…

πŸ§ πŸ‘‚ Dr Avi Chandra’s latest research links hearing lossβ€”especially centralβ€” to Alzheimer’s pathology including increased AΞ² and tau burden.

❓ But what is the underpinning relationship between these factors?

Watch this space!🧬🧩

To read more ⬇️

www.sciencedirect.com/science/arti...

09.07.2025 12:54 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
The front slide of a PowerPoint presentation. The text reads 'Reducing the risk of dementia: policy recommendations from a panel of experts'. Harriet Demnitz-King and Debs Smith.

The front slide of a PowerPoint presentation. The text reads 'Reducing the risk of dementia: policy recommendations from a panel of experts'. Harriet Demnitz-King and Debs Smith.

Debs Smith and Harriet Demnitz-King presenting

Debs Smith and Harriet Demnitz-King presenting

Great to be at the @spindnetworkplus.bsky.social Science Festival 2025 today πŸŽͺ

@hdemnitzking.bsky.social (Early Career Researcher at #denpruQM) and Patient and Public Engagement Group member Debs Smith presented findings from our consensus workshop on public health policy for dementia prevention.

02.07.2025 14:03 β€” πŸ‘ 6    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0
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Causes and consequences of vascular dementia across the life course: Evidence from a UK Biobank phenome-wide and Mendelian randomization study Background Vascular dementia (VaD) is the second most common cause of dementia, yet its risk factors and biological mechanisms remain poorly understood. Objective To identify causes and consequences ...

Fabulous work by Phazha Bothongo!

2 years and several near mental breakdowns for us both in the making!

🧠 Causes and consequences of vascular dementia across the life course: Evidence from a UK Biobank phenome-wide and Mendelian randomization study 🧠

www.medrxiv.org/content/10.1...

25.06.2025 16:06 β€” πŸ‘ 9    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

Listen here➑️

Curious how divorce and widowhood affect the brain? 🧠

Take a deep dive into how these major life events may be linked to cognitive decline with Dr. Avi Chandra in the latest episode of ISTAART Voices.

πŸŽ™οΈ Listen now: alz.org/ISTAARTpodcast

23.04.2025 13:44 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Quick Check Needed

πŸ’Ό We're looking for a mixed methods Research Assistant to join our team from August.

πŸ“ˆ You'll work across a range of projects utilising quantitative & qualitative methods, which may include health economics.

⏰ Apply via our website by Tuesday 6th May: shorturl.at/NxSqe

Please share widely!

16.04.2025 09:07 β€” πŸ‘ 1    πŸ” 8    πŸ’¬ 1    πŸ“Œ 0
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Research Assistant: Equitable health and social care Join NIHR DeNPRU-QM at Queen Mary as a Research Assistant to support dementia & neurodegeneration policy research. 18-month role starts after 6 Aug 2025.

Join NIHR DeNPRU-QM at Queen Mary as a Research Assistant to support dementia & neurodegeneration policy research. 18-month role, apply by 6th May @denpru-qm.bsky.social

www.dementiaresearcher.nihr.ac.uk/job/research...

16.04.2025 10:17 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1

Come and work with us! Excellent research and policy research experience in a supportive socially active team

11.04.2025 12:44 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
Postdoctoral Research Associate - QMUL Jobs ID: 5343. Title: Postdoctoral Research Associate. Application Deadline:

πŸ“£ We're recruiting a mixed methods Postdoctoral Research Associate to join our team from August 2025 πŸ“£

You'll have a PhD (or near completion) & enjoy working with large data sets. Apply here:

shorturl.at/Z4SHk

@claudiacooper.bsky.social @qmulpsychiatry.bsky.social @dementiaresearcher.bsky.social

11.04.2025 09:52 β€” πŸ‘ 5    πŸ” 8    πŸ’¬ 2    πŸ“Œ 1

Please do think of joining us or pass this on to someone you know who might fancy it. I am, of course, rather biased but I think we are a lovely bunch, trying to help answer some really important questions. Always happy to chat to anyone who is interested!

09.04.2025 17:15 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1
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Detecting early neurovascular dysfunction in Alzheimer’s Disease and Cerebral Amyloid Angiopathy (CAA) at University College London on FindAPhD.com PhD Project - Detecting early neurovascular dysfunction in Alzheimer’s Disease and Cerebral Amyloid Angiopathy (CAA) at University College London, listed on FindAPhD.com

Excited to share a new PhD studentship, using fMRI and MEG to detect early changes in Alzheimer's disease, fully funded for a UK student by @alzheimersresearchuk.org . Situated at UCL in Queen Square, London. Join us! tinyurl.com/nvmgroupphd

02.04.2025 10:40 β€” πŸ‘ 16    πŸ” 6    πŸ’¬ 1    πŸ“Œ 1
Oriel Published vacancies that are available for applicants to apply to. This includes key information suchs as the training programme(s), post type(s), advert information and duration.

🚨Fantastic job opportunity for neurology trainees

Neurology Clinical Lecturer post in Dementia with us @qmuldementia.bsky.social now open to applications!

Please DM me for info and to discuss

www.oriel.nhs.uk/Web/PermaLin...

19.03.2025 13:11 β€” πŸ‘ 3    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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Early presentations of dementia in a diverse population INTRODUCTION Improved recognition of non-cognitive presentations of dementia could reduce inequalities in dementia diagnosis, particularly if sociocultural factors influence help-seeking for cogniti...

Early presentations of dementia in a diverse population alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

27.02.2025 14:44 β€” πŸ‘ 7    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

I think yes to both. We also need to look at combinations of features and consider the idea of automated dementia risk flags in primary care in the next phase.

26.02.2025 16:06 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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New research, born out of community engagement work, shows that the symptoms people report prior to receiving a dementia diagnosis vary across ethnic groups.

www.qmul.ac.uk/media/news/2...

@qmulfmd.bsky.social @charlesmarshall.bsky.social @alzassociation.bsky.social @alzheimerssoc.bsky.social

26.02.2025 13:34 β€” πŸ‘ 18    πŸ” 11    πŸ’¬ 0    πŸ“Œ 2

Thanks and congrats to the whole team involved @qmulpsychiatry.bsky.social @qmuldementia.bsky.social @preventiveneur1.bsky.social

26.02.2025 12:43 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Early presentations of dementia in a diverse population INTRODUCTION Improved recognition of non-cognitive presentations of dementia could reduce inequalities in dementia diagnosis, particularly if sociocultural factors influence help-seeking for cogniti...

What symptoms do people tell their GP about when they are developing dementia?

Lots of non-cognitive symptoms - and in a highly diverse population we can see that it is culturally influenced.

Recognising this is key to equitable diagnosis

alz-journals.onlinelibrary.wiley.com/doi/full/10....

26.02.2025 12:42 β€” πŸ‘ 27    πŸ” 12    πŸ’¬ 2    πŸ“Œ 1
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Introducing Avi πŸŽ‰!

He is a postdoctoral research assistant at CPN, working on the ABATED project to advance automated brain image analysis for equitable dementia diagnosis. He completed his PhD at King’s, focusing on genetics and in vivo biomarkers in MCI & AD.

Watch to hear from Avi!

21.02.2025 16:37 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Sage Journals: Discover world-class research Subscription and open access journals from Sage, the world's leading independent academic publisher.

πŸŽ‰Excited to share the first published output from the ABATED studyπŸŽ‰

The commentary in JAD, "Cultural variation in trust and acceptability of AI diagnostics for dementia," explores key considerations from diverse focus groups, focusing on trust, training, and autonomy.

doi.org/10.1177/1387...

17.02.2025 12:22 β€” πŸ‘ 2    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Introducing Natalia πŸŽ‰!

She is a NIHR Doctoral Fellow in CPN's Dementia team. Her PhD research explores Alzheimer's blood biomarkers in ethnic minority groups, supervised by Prof, @charlesmarshall.bsky.social , Prof @claudiacooper.bsky.social & Dr. Ashvini Keshavan (UCL).

14.02.2025 13:06 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

ICYMI: New online! Moving towards meaningful patient and public engagement https://bit.ly/4aUOcs2

12.02.2025 00:54 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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ICYMI: New online! Nothing about us, without us β€” establishing a patient and public involvement and engagement group https://bit.ly/4aUOfEe

12.02.2025 00:54 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Distinct spatiotemporal atrophy patterns in corticobasal syndrome are associated with different underlying pathologies Scotton et al. report distinct subtypes of atrophy progression in corticobasal syndrome identified using machine learning analysis of structural MRI scans.

academic.oup.com/braincomms/a... delighted to finally see this out. We asked the question - could we identify different subtypes of CBS using SuStaIn algorithm applied to a baseline structural MRI scan and if so did these associate with underlying pathology? Read the paper to find out!

12.02.2025 07:38 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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We’re revisiting the insightful focus group we held for the DIADEM project six months ago.

A huge thank you to everyone who participated and contributed to the valuable discussions. Your involvement continues to drive the progress of our research.

06.02.2025 12:12 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

@charlesmarshall is following 20 prominent accounts