Antonio Regalado

The ads that sell the sizzle of genetic trait discrimination A startup’s ads for controversial embryo tests hit the New York City subway.

Have a smarter baby? You might, but it's not necessarily legal to advertise. Our look at the NYC subway ad campaign by IVF embryo profiling company Nucleus and how it collides with anti-discrimination statutes that apply to advertising on public property.
www.technologyreview.com/2025/12/05/1...

yeah. Several topics on which Grok argues forcefully from evidence that isn't great.

Thanks for making the case. You are right it's a perennial candidate, but the Presidential sh*t coin takes it extra. What's the best factual coverage you've seen?

lol. great.

people are saying. but DOGE is not a technology per se. hard to shoehorn in, though Im open to ways

Yeah, we had "AI Slop" on the list last year. I hate Google's AI suggestions in particular, but are they are failure or actually Google's bold and successful move to self-disrupt search.

I am preparing MIT Technology Review's infamous list of "worst" technologies of the year.

What are 2025's biggest failures, set backs, and misfires but which also hold useful lessons about technology?

I think Cybertruck has to be on the list. Tell me your picks in the replies👇!!

I think the matter at hand is not a prediction of ultimate IQ, but predicting which of two or more sibling embryos is likely to have higher IQ and by what degree.

A month after Bari Weiss hired to lead CBS News division, heretic eugenics philosopher Jonathan Anomaly is on the morning show pitching bell curves and embryo scores.

www.youtube.com/watch?v=qvVM...

I tremendously enjoyed Matthew Cobb’s definitive new biography of Crick. It was hard to put down and provides many new perspectives. My review of it will appear in Science later this week.

Here’s the latest company planning for gene-edited babies Entrepreneurs say it’s time to safety-test designer baby technology.

A 3rd (?) germline editing co announced @antonioregalado.bsky.social in @technologyreview.com, www.technologyreview.com/2025/10/31/1...
I mainly share Fyodor's reaction, quoted in story—"In his email, Urnov said the launch of still another venture into the area made him want to “howl with pain.”

#password

Here's an archived copy of his article that gets you past the paywall. web.archive.org/web/20251021...

The astonishing embryo models of Jacob Hanna Scientists are creating the beginnings of bodies without sperm or eggs. How far should they be allowed to go?

The astonishing science of synthetic embryology and our profile of it's most ambitious praticioner, Jacob Hanna

www.technologyreview.com/2025/10/21/1...

Read this item by TB researcher whose grant got cancelled as 'dangerous gain of function.'

Ironic, because the administration (RFK), has promoted whole‑virus vaccines, whose development, especially if they are attenuated, probably relies on very similar techniques.

69.97% certain he's referencing something he heard from people with relevant expertise. IVF clinics have nothing if not aneuploid embryos at hand.

anyway, FYI, here is a person will billions in crypto proposing something (unspecified) about trisomy KO on the other site.

Right. I am not sure of the tactic, but you can see it's interesting to strategize how to get rid of a trisomy.

I see the figures thanks for the link.

My q has been: i rob(14;21) such as case? Based on the chart seems like if a carrier generated many embryos some would be unaffected?

cool. evo theory. These robs are a potential target of CRISPR. Use it to shred the extra bit (in zygote i guess). Some seek a situation/justification where germline editing would be *necessary* to obtain a healthy embryo (i.e. can't be done via embryo selection).

thanks for posting. this is a very confusing phenomenon

AI-designed viruses are here and already killing bacteria Can AI create a life form? These “generative” genomes are a start

Here come the first "generative" genomes. Folks at the Arc Institute used an AI trained on DNA sequence to propose code for novel bacteriophage genomes.

Of the 302 they synthesized, 16 actually worked--replicating and killing E. Coli.

www.technologyreview.com/2025/09/17/1...

AI-designed viruses are here and already killing bacteria Can AI create a life form? These "generative" genomes are a start

Can AI create a life form? These "generative" genomes are a start. New from @antonioregalado.bsky.social

www.technologyreview.com/2025/09/17/1...

Can anyone find a Berman MF et al. Neurotoxicology 2008; 29(5), 914–922 ?

This is a fake citation.
www.sciencedirect.com/journal/neur...

yeah. thanks. it does sound like that is what she is saying.

can you point me to where she makes this claim made? thanks. just want to see the source because..interesting if true.

how do you know Musk employed gender selection.

World famous synthetic embryo scientist stopped while entering U.S.

Agent: Any embryos in your luggage?

Scientist: One sec.

[Opens guideline booklet of the International Society for Stem Cell Research.]

Scientist: Nope, just 3-D structures derived from pluripotent stem cells.

I call it business-casual eugenics