João Ferreira Fernandes's Avatar

João Ferreira Fernandes

@immjoao.bsky.social

Postdoc @ucl.ac.uk | Visiting Scientist @crick.ac.uk | Formerly DPhil @ox.ac.uk @imm.ox.ac.uk

59 Followers  |  152 Following  |  2 Posts  |  Joined: 06.03.2025  |  1.4331

Latest posts by immjoao.bsky.social on Bluesky

From the ɑβ- and γδ-TCR to important checkpoint inhibition targets like PD-1 and CTLA-4, this review gives focus to the important previous contributions from @imm.ox.ac.uk and collaborators to this field.

@ox.ac.uk @rdmoxford.bsky.social @imm.ox.ac.uk
(with @sumanasharma.bsky.social)

04.04.2025 09:45 — 👍 0    🔁 0    💬 0    📌 0
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The Structural Biology of T‐Cell Antigen Detection at Close Contacts T cells physically interrogate their targets using tiny membrane protrusions called microvilli, forming junctions ~400 nm in diameter and ~ 15 nm deep, referred to as “close contacts”. These contacts...

Happy to share that our review on the structural biology of T-cell surface proteins is out in Immunological Reviews.

Here we describe the ways in which crystal structures and cryo-EM have informed our understanding of receptor behaviour and T-cell biology.

onlinelibrary.wiley.com/doi/full/10....

04.04.2025 09:45 — 👍 3    🔁 0    💬 1    📌 0
Preview
Wellcome Career Development Award For Sumana Sharma Dr Sumana Sharma has won a Wellcome Career Development Award for her research investigating receptors in T cells.

Congratulations to Dr Sumana Sharma (@sumanasharma.bsky.social), who has won a Wellcome Career Development Award for her research investigating receptors in T cells 🎉

Read more: www.imm.ox.ac.uk/news/wellcom...

@rdmoxford.bsky.social | @wellcometrust.bsky.social

14.03.2025 10:56 — 👍 3    🔁 1    💬 0    📌 1

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