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Charles de Bock

@charles-debock.bsky.social

Cancer Researcher #bloodcancer #leukemia #functionalgenomics #TCellLeukemia. Group Leader at Children's Cancer Institute, Sydney. https://bit.ly/3zxhpW6

463 Followers  |  164 Following  |  25 Posts  |  Joined: 12.11.2024
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Posts by Charles de Bock (@charles-debock.bsky.social)

Abstract submission just opened for #ISEH2026 in Frankfurt. Outstanding scientific program; welcoming community; and more than double the number of short talk slots for abstract to be presented in. Looking forward to seeing you there. @isehsociety.bsky.social

06.02.2026 07:29 β€” πŸ‘ 9    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

A wonderful discussion with Anika Sijs-SzabΓ³ from Erasmus MC and Leiden University Medical Center and Roger Mulet Lazaro from Erasmus MC on their work improving the classification of #ALAL cases published in @hemasphere-journal.bsky.social .

Tune in to find out how collaboration fuels discovery!

01.11.2025 21:48 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Another great conversation on NUP98-rearranged #AML and the use of #Menin inhibitors. Plus some hot tips on how to measure cytotoxicity in co-culture systems and finally, how to pronounce #MEIS1. Listen below and subscribe where ever you get your podcasts from @hemasphere-journal.bsky.social

05.09.2025 10:41 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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🎧REPLAY!

In this episode host Dr Charles de Bock discusses the role of mouse models in understanding leukemogenesis & hematopoiesis w/ Prof Richard Lock: https://bit.ly/40Ch3NP

Listen & enjoy casual, insightful discussions about #hematology research.

22.08.2025 11:24 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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We are honoured to welcome Professor John D. Crispino, from
@stjude.bsky.social as speaker to #NDLR2026. John’s research focuses on mechanisms of #Leukemia development in children with Down syndrome and the malignant progression of #MyelodysplasticSyndrome and #MyeloproliferativeNeoplasms.

19.08.2025 23:55 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Amazing work @bethpsaila.bsky.social and whilst platelets are certainly not my area, this is a paper that I will be digging into more. Congratulations to the entire team.

15.08.2025 10:04 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Welcome back downunder!

05.08.2025 08:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The NIC welcomes speakers Hanna Mikkola and Elizabeth Ng who will present their latest research on stem cell development and regeneration at the 20 August webinar on Human HSC Ontogeny. Register now www.iseh.org/ISEHWebinars

31.07.2025 21:01 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Also - Super interested to hear from listeners. As host, I want to improve. Are the podcasts too long? too short? Need to have more clinical focus? More basic science focus? You want to know more about the technical side? Do I talk too fast? talk to slow? Are there topics you want to hear more on?

01.08.2025 06:10 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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HemaSphere Podcast Medicine Podcast Β· Updated Monthly Β· HemaSphere is the official online, open access journal of the European Hematology Association (EHA). HemaSphere publishes exciting basic, translational, and clinic...

So the latest @hemasphere-journal.bsky.social Podcast is out! This time all about Metabolism. You can subscribe podcasts.apple.com/au/podcast/h... to get all the podcasts direct into your feed. Each is around 30 min, perfect for that commute to work.

01.08.2025 05:01 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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Hypomethylating agents induce epigenetic and transcriptional heterogeneity with implications for acute myeloid leukemia cell self-renewal - Leukemia Leukemia - Hypomethylating agents induce epigenetic and transcriptional heterogeneity with implications for acute myeloid leukemia cell self-renewal

I'm pleased to share that Leukemia have published our analysis of heterogeneous responses to hypomethylating agents #HMAs in Acute Myeloid Leukaemia #AML
www.nature.com/articles/s41...

28.07.2025 20:09 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0

This was very happy news to arrive to today! Thank you to our authors, reviewers, and readership for your continued support. We are glad to know that everyone's hard work is well-appreciated.

18.06.2025 15:47 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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🚨Today! @ 15:45, MiCo room CORAL 6 
We warmly invite you to the HemaSphere Scientific Session where we will diveΒ into 3 of our exciting + cutting-edge biology publications. Hope to see you there!
πŸ•°οΈ: 15:45 - 16:45
πŸ“: Room CORAL 6, #EHA2025
🎀: https://bit.ly/4koLwXk

14.06.2025 10:02 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Don’t miss the second YERM Session on β€žNew insights into clonal hematopoiesisβ€œ at 10 oβ€˜clock in Brown Hall 2!
#EHA2025 #YoungEHA #Hematology

14.06.2025 07:41 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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The team representing @kidscancerinst.bsky.social at #EHA2025 @hansenjk.bsky.social Faezeh Khalili, Jackie Huang, Yashna Walia

12.06.2025 16:59 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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We are HemaSphere proud at #EHA2025, where 2 of our editors received special EHA awards! Congrats to Jan Cools, Ed in Chief, for the education & mentoring award; and to Mandy Lauw, Scientific Ed, for the YoungEHA award. Well deserved πŸ‘ @jancools.bsky.social @mandylauw.bsky.social

12.06.2025 12:41 β€” πŸ‘ 11    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
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Honoured to have been a mentee of @jancools.bsky.social who is this years #EHA2025 Education and Mentoring award winner. Amazing and recognising his unwavering support for so many researchers!

12.06.2025 10:45 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Dr C de Bock hosts co-authors Dr F Fioredda & Dr E Papadaki to discuss Guidelines for treating neutropenias. Delve into the importance of international guidelines, challengesΒ  βž• more. 🎧 https://bit.ly/42O9l4v.

Part 1: 2023 neutropenia Guidelines, diagnosis &management #2025HemaSphereAward winner πŸ†

12.06.2025 08:03 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Next up is Dr Hansen Kosasih @hansenjk.bsky.social looking at cis-regulome of AKR1C3 which activates super prodrug ACHM-025 and can eradicate T-ALL. He is speaking today at #EHA2025 molecular Hematopoiesis workshop. Plus poster PS1332 @kidscancerinst.bsky.social

12.06.2025 08:26 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Where is the hemaSphere hut? Trying to find youπŸ‘€

12.06.2025 07:59 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Yes! I will look out for you!

12.06.2025 07:58 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

For #EHA2025 our group has Phd Candidate Yashna Walia doing in vivo PDX dual gRNA screen of epigenetic regions looking into GR resistance. Check out Poster PS1334 @kidscancerinst.bsky.social

12.06.2025 07:56 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Hello #EHA2025. Happy to be here with my group this week. Connecting with old friends and colleagues and making new friends this week. Let me know if you are around!

12.06.2025 05:25 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Hello #EHA2025. Happy to be here with my group this week. Connecting with old friends and colleagues and making new friends this week. Let me know if you are around!

12.06.2025 05:23 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Looking forward to attend the #EHA2025 @hemasphere-journal.bsky.social sessions next week!

08.06.2025 06:35 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Heading to #EHA2025 in Milan in 1.5(ish) weeks? HemaSphere has 2 exciting sessions on the program!
πŸ“ŒPeer Review Workshop: Fri 13 June, 13:30 - 15:00
πŸ’‘Learn + master the peer review role/process
πŸ“ŒHemaSphere Scientific Session: Sat 14 June, 15:45 - 16:45
πŸ’‘Dive into 3 of our cutting-edge biology papers

29.05.2025 08:03 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Patient‐derived xenografts: Practical considerations for preclinical drug testing Click on the article title to read more.

This HemaTopic by Sci Ed C de Bock discusses using PDXs for testing leukemia therapies, focusing on PDX model maintenance, immunodeficient mice & standardized reporting for preclinical drug testing. It also ties in a recent HemaSphere podcast with Prof Richard Lock.Β  See bothπŸ‘‰

16.05.2025 08:30 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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New Episode!
Dr. Charles De Bock hosts Prof Jan Cools, Prof Heidi Segers & Dr Margo Aertgeerts to discuss advancements in ALL treatment, challenges of relapse & innovative use of SCS to uncover genetic mutations & clonal composition. Listen to their insightful discussion 🎧 bit.ly/42N3cWx

07.05.2025 08:31 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

We are recruiting!! Ads now live for a Data Coordinator and 2 Research Assistants/biobankers to join a new @ludwigcancer.bsky.social - @imm.ox.ac.uk joint initiative to prevent progression from early- to advanced blood cancer. Joint posts with Adam Mead+others in Oxford Ludwig. Links below

27.03.2025 07:59 β€” πŸ‘ 16    πŸ” 11    πŸ’¬ 1    πŸ“Œ 0

We have put together an amazing line-up of invited speakers and talks selected from abstracts for the 2nd Annual ISEH Mini-Symposium!!! Join us online on March 26th (free for ISEH members) to learn what’s new and exciting in Experimental Hematology!!! @isehsociety.bsky.social

20.03.2025 11:55 β€” πŸ‘ 9    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1