Rupinder Kaur

Absolute quantification of prokaryotes in the microbiome by 16S rRNA qPCR or ddPCR - Nature Protocols This protocol enables rigorous and reproducible quantification of prokaryotic concentration in stool samples by 16S rRNA qPCR or ddPCR.

🧪🔬🦠🧫🌍
This is the kind of paper we should all be waiting for!

Because sadly we still don't have reliable methods to count bacterial abundance from microbiomes.

(I haven't read it yet, but I love the intention already)

www.nature.com/articles/s41...

PLEASE SHARE We’re hiring a contract #bioinformatician (research officer) to analyse #microbiome data from an ongoing, exciting project focusing on preterm birth prevention with oral probiotics

topjobs-teagasc.thehirelab.com/LiveJobs/Job...

📝 In this month's editorial, we talk about the power of mathematical modeling 🧮, its importance in understanding of complex microbiology 🦠 , and how we assess papers addressing mathematical modeling.

Read more: www.nature.com/articles/s41...

Share your thoughts in the replies!

#MicroSky #MathSky

Life-long microbiome rejuvenation improves intestinal barrier function and inflammaging in mice - Microbiome Background Alterations in the composition and function of the intestinal microbiota have been observed in organismal aging across a broad spectrum of animal phyla. Recent findings, which have been der...

1/7: Proud to present our next study on aging microbiome - a massive experimental effort led by the Rosenstiel and Sommer labs and contributions by @sci-witch.bsky.social. @uni-kiel.de @crc1182.bsky.social microbiomejournal.biomedcentral.com/articles/10....

And here is a press release covering our work on host-microbiome-interactions in aging: www.precisionmedicine.de/de/das-mikro...

Metabolic modelling reveals the aging-associated decline of host–microbiome metabolic interactions in mice - Nature Microbiology A multi-omics approach reveals host–microbiome interactions in aging in mice.

1/12 Thrilled to share our latest paper on host-microbiome-interactions in aging out in Nature Microbiology @naturemicrobiol.bsky.social, great work led by Lena Best @sci-witch.bsky.social with the Frahm lab within the ITN SmartAge. @crc1182.bsky.social @uni-kiel.de
www.nature.com/articles/s41...

Multi-omic stock of surface ocean microbiome built by monthly, weekly and daily sampling in Dapeng Bay, China - Scientific Data Scientific Data - Multi-omic stock of surface ocean microbiome built by monthly, weekly and daily sampling in Dapeng Bay, China

Multi-omic stock of surface ocean microbiome built by monthly, weekly and daily sampling in Dapeng Bay, China www.nature.com/articles/s41... #jcampubs

RNA xkcd.com/3056

1/3 🌍 We're hiring! The Medical Systems Biology Lab at Kiel University @uni-kiel.de is looking for a #PostDoc in #Metabolic #Microbiome #Modeling. Join us at one of Europe’s microbiome research hubs and push the boundaries of microbiome science!
🔗 jobs.uksh.de/job/Kiel-Pos...

Interested in doing a PhD in Austria focused on understanding how to engineer the composition of the gut microbiota?

Want to work with a brilliant computational biologist and microbiome researcher?

See below!

Excited to share our overview on SynCom construction published in @cp-trendsmicrobiol.bsky.social

@xinmingxu.bsky.social & @neftalyl.bsky.social together with Caja Dinesen & Adele Pioppi summerize 86 publications on SynComs for plant promotion

free download: authors.elsevier.com/a/1kdNr_,2Ci...

Understanding and predicting microbial evolutionary dynamics - 2025 meeting

I'm delighted to announce that the 2025 @microbiologysociety.org meeting on "Understanding and predicting microbial evolutionary dynamics" will be held in Liverpool 26-27 November 2025! Abstract submission will open soon... #microsky 🧪🧫🦠 microbiologysociety.org/event/societ...

GitHub - YongxinLiu/MicrobiomeStatPlot: Interpretation and visualization of microbiome charts Interpretation and visualization of microbiome charts - YongxinLiu/MicrobiomeStatPlot

MicrobiomeStatPlots: #Microbiome statistics plotting gallery for meta‐omics and #bioinformatics
Available on GitHub: github.com/YongxinLiu/M...
onlinelibrary.wiley.com/doi/full/10....

Metagenomic estimation of dietary intake from human stool - Nature Metabolism Diener et al. present a method that allows the estimation of dietary intake from human stool by detecting food-derived DNA in faecal metagenomes.

Happy to announce that MEDI, our method to quantify dietary intake through metagenomics is out now. 🧬 🧪🧫🦠 www.nature.com/articles/s42...

#metagenomics #microbiome #microbiomesky

So what is MEDI? A combination of two things:

Here's an exciting opportunity for a PhD studentship to study #biofilms and #microbiomes in the food chain with @drlauranolan.bsky.social at SCELSE @scelse.bsky.social.
I highly recommend!
🧪🧫

Temporal stability and lack of variance in microbiome composition and functionality in fit recreational athletes - Scientific Reports Scientific Reports - Temporal stability and lack of variance in microbiome composition and functionality in fit recreational athletes

No significant differences in gut #microbiome composition or function were observed in relation to fitness, training volume

www.nature.com/articles/s41...

Is precision microbiome medicine just around the corner? Nature Reviews Gastroenterology & Hepatology, Published online: 04 February 2025; doi:10.1038/s41575-025-01040-4A study in Nature Medicine developed a new clinical test based on a gut metagenome-derived multispecies biomarker panel for the diagnosis of…

New online! Is precision microbiome medicine just around the corner?

Diversity in women and their vaginal microbiota Women’s health is essential to global societal and economic wellbeing, yet health disparities remain prevalent. The vaginal microbiota plays a critical role in health, with research indicating that re...

📢Sarah Lebeer (@sarahlebeer.bsky.social) and colleagues at the Isala team call for a more comprehensive, global, and inclusive understanding of the #vaginal #microbiome, critically reflecting on the use of 'race' and 'ethnicity' in studies.

Read the Opinion piece here: www.cell.com/trends/micro...

An atlas of metabolites driving chemotaxis in prokaryotes - Nature Communications In this meta-analysis, the authors compile results from 60 years of chemotaxis research into a database of prokaryotic chemoeffectors that compares and analyses their effects as attractant, repellent ...

An atlas of metabolites driving chemotaxis in prokaryotes

-in @naturecomms.bsky.social from Jean-Baptiste Raina

60 years & 341 publications ➡️ comprehensive database of prokaryotic chemoeffectors: 926 chemicals previously tested; chemotactic behaviour of 394 strains

www.nature.com/articles/s41...

Schematic overview of the PhD; combining bacterial genomes from a large collection to analyse adhesins, metabolic potential, bacterial warfare; and compare to other arthropod symbiontes and design a minimal microbiome.

#PhD alert, here @unistrathclyde.bsky.social in the very friendly, diverse, artsy & welcoming city of Glasgow 🏴󠁧󠁢󠁳󠁣󠁴󠁿

Disentangling the functional modules of #mosquito #microbiomes - what puzzle pieces build our #holobionts?

#MicroSky #MicrobiomeSky 💻🧬🧪

More here 😊 www.strath.ac.uk/studywithus/...

Pannagram: unbiased pangenome alignment and the Mobilome calling https://www.biorxiv.org/content/10.1101/2025.02.07.637071v1 🧬🖥️🧪 #Rstats https://github.com/iganna/pannagram

Could Humans Have a Brain Microbiome? The discovery that other vertebrates have healthy, microbial brains is fueling the still controversial possibility that we might have them as well.

Very cool study that could have interesting implications for #MentalHealth and the human as #holobiont. www.wired.com/story/fish-h...

#science #scicomm #fish #vertebrates #brains #GutBrainAxis #microbiomes #microbiology #nature #animals

Longitudinal phage–bacteria dynamics in the early life gut microbiome - Nature Microbiology Reanalysis of 12,262 longitudinal infant gut microbiome samples using the Marker-MAGu pipeline revealed phage–bacteria dynamics over the first year of life.

We interrupt your regularly-scheduled chaos to bring you some cool microbiome science. 🦠 🖥️ 🧬
"Longitudinal phage–bacteria dynamics in the early life gut microbiome" now out in Nature Microbiology.

We wanted a way to measure bacteria and phage in metagenomes 1/

www.nature.com/articles/s41...

Deadline approaching! Free workshop on #Spatial #Microbiomics – From Sampling to Analysis"
Join us in May in #Copenhagen at
@hologenomics.bsky.social Ideal for PhDs, postdocs & other microbiome enthusiasts. Register until February 16th: www.3domics.eu/TrainingEven...
Please share!

Longitudinal phage–bacteria dynamics in the early life gut microbiome - Nature Microbiology Reanalysis of 12,262 longitudinal infant gut microbiome samples using the Marker-MAGu pipeline revealed phage–bacteria dynamics over the first year of life.

OUT NOW: Longitudinal phage–bacteria dynamics in the early life gut microbiome

www.nature.com/articles/s41...

We are moving to bluer pastures - a warm welcome to the members of the Medical Systems Biology lab on BlueSky:
Andy @andymega.bsky.social, Karlis @kamoors.bsky.social , Rupi @rupyr19.bsky.social , Poom @snatchapon.bsky.social , Len @sci-witch.bsky.social and Thomas @tdost.bsky.social

I could download the article and share it with you through email.

Gut microbial-derived phenylacetylglutamine accelerates host cellular senescence - Nature Aging Yang et al. show an age-related increase in the microbial-derived metabolite phenylacetylglutamine that drives host cellular senescence by inducing DNA damage and mitochondrial dysfunction via ADR–AMP...

Looks interesting: "Gut microbial-derived phenylacetylglutamine accelerates host cellular senescence" www.nature.com/articles/s43...

Anybody have access and want to share the pdf?

Worm people: We are looking for a postdoc to join the C. elegans Mentor Match committee.

This is a great opportunity to shape a global mentorship program and gain leadership experience.

📩 DM or email me and Andrea Calixto if interested—and please spread the word! 🙌

Collective dynamical regimes predict invasion success and impacts in microbial communities - Nature Ecology & Evolution Predicting invasion outcomes in microbial communities is challenging. Here the authors demonstrate that these outcomes in both theoretical and experimental microbial communities can be predicted based...

Collective dynamical regimes predict invasion success and impacts in microbial communities www.nature.com/articles/s41... #jcampubs