Carolina Makowski

So grateful to co-authors including @goliashf.bsky.social, @agrethe.bsky.social & @cwierengaphd.bsky.social, funding from the NIMH, and the UCSD Eating Disorders Center for data collection efforts! @psychiatryucsd.bsky.social

Multivariate patterns linking brain microstructure to temperament and behavior in adolescent eating disorders Molecular Psychiatry - Multivariate patterns linking brain microstructure to temperament and behavior in adolescent eating disorders

Super happy to see our latest research on multivariate brain-behavior patterns in adolescent eating disorders out in Molecular Psychiatry!

🔗Link to paper: rdcu.be/ewxpg

🗣️Lay summary thread of our work: tinyurl.com/dscnhduf

The ABCD Study 6.0 release is finally here! 🧠 Apply for data access here @theabcdstudy.bsky.social www.nbdc-datahub.org

Do you use ABCD study data and/or are interested in shaping the next phase of the study? Please join our roundtable in mezzanine 3! @ohbmofficial.bsky.social #OHBM2025

Super excited to be in Brisbane! Come check out new work from our group using ABCD study data and clinical data with the ABCD imaging protocol!

Don’t miss more exciting research and discussion from our team:

Roundtable Discussion:
@cmakowski.bsky.social & @parekhpravesh.bsky.social
📅 Thursday, June 26th | ⏰ 13:00 - 14:00
“Shaping the Future of the ABCD Study: A Roundtable Discussion”

FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets Linear mixed-effects (LME) models are commonly used for analyzing longitudinal data. However, most applications of LME models rely on random intercepts or simple, e.g., stationary, covariance. Here, w...

Introducing FEMA-Long for high-dimensional large-scale mixed-effects modelling! Includes modelling unstructured covariance, non-linear effects using splines, time-dependent effects with spline interactions, and longitudinal GWAS with time-dependent genetic effects!
www.biorxiv.org/content/10.1...

🧠💊New preprint differentiating antipsychotic medication vs. illness effects on cortical thickness in people w/ psychosis.

Finding: People receiving placebo show prominent cortical thinning over 1st year of illness, whereas those receiving antipsychotics do not. 1/3

www.medrxiv.org/content/10.1...

an absolute tour de force! Congrats @goliashf.bsky.social & team!

🔍 New must-see resource! 🧠
--> Reproducible Brain Charts – an open-data tool for mapping brain development & mental health

www.biorxiv.org/content/10.1...

👏 Kudos to @ted-satterthwaite.bsky.social and Michael Milham @childmindinstitute.bsky.social for leading this effort!

Since good news feels rare these days, excited to share a win - My R00 was awarded! Will be looking for a postdoc soon to help uncover biological 🧠🧬 & behavioral prospective 📈factors for adolescent eating disorders 🍽️ @ucsdhealthsci.bsky.social @ucsdhealth.bsky.social

Mapping Lesions That Cause Psychosis This case-control study analyzes published cases of lesion-induced psychosisTo assess whether lesions that cause secondary psychosis have functional connections to a common brain circuit

jamanetwork.com/journals/jam...
Thread below👇

Synaptome architecture shapes regional dynamics in the mouse brain | www.biorxiv.org/content/10.1...

Led by Justine Hansen

Big news: there are all sorts of different synapse types in the brain 👀‼️⤵️

A Direct Hit, by @holdenthorp.bsky.social @science.org
www.science.org/doi/full/10....
"This is a moment to unite."