Masseck Lab

@massecklab.bsky.social @finkryan.bsky.social 🥳👏🧠🐭🔬🧪🩷

Fresh batch of Hot Plasmids here! Find new tools for:
🧠 Neural cell-surface proteomics
🔋 Nerve-to-cancer mitochondrial transfer @greletlab.bsky.social
🔬 Red calcium biosensors @massecklab.bsky.social & @piatkevich.bsky.social
✂️ CRISPRa-AAV for adipocytes @nadavahituv.bsky.social
& more!

Inhibitory inputs from thalamus promote resilient spiking in tail of striatum Neuroscience; Sensory neuroscience

Latest from the lab: Laura Haetzel finds that excitatory transmission from auditory thalamus to tail of striatum is accompanied by a sparse inhibitory projection. This allows for state-dependent control of striatal output.
www.cell.com/iscience/ful...

New plasmids available from the @massecklab.bsky.social‬! PinkyCaMP, a mScarlet-based calcium sensor, can be leveraged for its exceptional brightness, photostability, and multiplexing capabilities.
https://twp.ai/4iobS2

mScarlet3-H (aka mYongHong) is on the cover of Nature Methods! All plasmids are available for free from WeKwikGene wekwikgene.wllsb.edu.cn/publications...

📆 Mark your calendars: #OptoGRC2026 is headed back to Tuscany, May 10-15, 2026!

We look forward to reuniting with our amazing community for a week of great science, thoughtful discussions & shared time with colleagues.

More details coming soon👇🏽
tinyurl.com/esvrabsu

We’re hiring!
The Masseck Lab (University of Cologne) is looking for a full-time Technical Assistant (permanent position).
Focus: neuroscience, behavior experiments, and cell culture.
Apply by May 1st → jobportal.uni-koeln.de/ausschreibun...
#JobAlert #Neuroscience #LabTech #BTA #UniCologne

Neuroscience methods - YouTube Nanocourse: Approaches to Study Neural Circuits This course was taught by Anita Autry, Tiago Gonçalves, and Luke Sjulson at Albert Einstein College of Medici...

Neuroscience students asked us to teach a PRACTICAL course on experimental methods, and it is now on YouTube!

Please like and repost to help us get the word out!

www.youtube.com/playlist?lis...

Lecture 1: Signals and data acquisition
Focusing on hardware, digital/analog I/O, synchronization
🧵

The first PinkyCaMP plasmids are now available on Addgene🧬… more coming soon 🚀! Stay tuned!

www.addgene.org/Olivia_Masse...

First PinkyCaMP plasmids are available via @addgene.bsky.social

www.addgene.org/browse/artic...

Cc @finkryan.bsky.social @massecklab.bsky.social

Poster for ECS Webinar with speakers Robert Campbell snd Sarah Shaykevich.

I, along with Dr. Sarah Shaykevich, will be speaking about red and near-infrared genetically encoded Ca2+ biosensors in the European Calcium Society (ECS) webinar on Wednesday, February 26th at 5 PM CET. This webinar series is open to everyone!

docs.google.com/spreadsheets...

Hey, thank you for your kind words! We have not yet tried but the chances are low as for mScarlet 920 is not really optimal. However, we are already trying to make a long stoke shift version based on LSSmScarlet. I‘ll keep you posted on that.

All imaging approaches, including single-photon excitation methods such as fiber photometry, widefield imaging, miniscope imaging, as well as two-photon imaging in awake mice, are fully compatible with PinkyCaMP!

🎄PinkyCaMP- our christmas gift to you! 🎁: We are excited to present PinkyCaMP, the first mScarlet based calcium sensor with:
✨exceptional, brightness
✨phototability
✨and optogenetic compatability.
Check out our new preprint:
www.biorxiv.org/content/10.1...