Cass Dale Condray

journals.lww.com/ajg/pages/pa...
Read it here!

Algorithms are great, but it’s important to use them critically and with discretion and to ensure you aren’t using a tool designed/validated without your patient population in mind

FAIRS — A Framework for Evaluating the Inclusion of Sex in Clinical Algorithms | NEJM If sex-based differences in risk result from biased care rather than biology, enshrining the associations in clinical algorithms may be inequitable and unlawful. How can appropriate boundaries be ...

The FAIRS framework is a novel clinical decision making framework that posits that maybe we don’t always have to stratify clinical decisions by a patients assigned sex at birth (or what we assume that to be)!

www.nejm.org/doi/full/10....

Excited to share that our paper analyzing FAIRS analysis of sex based algorithms in gastroenterology and hepatology was accepted for publication in AJG!

Cass(me) and Victor with my poster on our survey we created!

Presenting our poster on sex linked algorithms in GI!

Cass and Chris Velez presenting his award

Me (cass) by my poster!

Belated post, but a fantastic first ACG presenting two posters (starring the one and only @victorchedidmd.bsky.social )
Over the moon honored to receive a @rainbowingastro.bsky.social travel award as well ⭐️
Learned so much and had a great time!

If you are LGBTQ+ and have IBD, please consider taking this survey!!

www.surveymonkey.com/r/IBDLGBTQIA

academic.oup.com/crohnscoliti...
Just published! Excited to see this project reach this milestone - very important to me and a critical area of research!

🌈 #RIG #PRIDE member highlight🌈
Meet @cdalecondray.bsky.social, recent BSc Microbiology grad🎓 U Oklahoma & founder of prideandpoop.com 🌈

At #RIG, we welcome folks from all training backgrounds, gender identities, and sexual orientations! 🫶

Join us rainbowsingastro.org

#GISky

👋Our June issue's out!
Cover: #Ferroptosis hotspots

👉🏼Editorial on #microscopy reporting
👉🏼Review on #mitochondria membrane
🔬 #cholesterol transport #neutrophils #exosomes #CellDeath #RNA #DNArepair #BreastCancer #ExtracellularVesicles #peroxisome proteins & more!
www.nature.com/ncb/volumes/...

Our June 2025 issue is out now - www.thelancet.com/gastrohep

Including research in irritable bowel syndrome, inflammatory bowel disease, & rectal cancer plus reviews on the intestinal barrier & prevention in IBD, plus lots more content!

#gastrosky #medsky #oncsky #ibdsky

House Passes 'Big, Beautiful Bill' That's a Vicious Attack on Abortion and Gender-Affirming Care The budget bill would "defund" Planned Parenthood, closing nearly 200 clinics, and prohibit Medicaid from covering healthcare for transgender people, no matter their age.

The bill wouldn't just cause millions to lose their health insurance, it would also:
*ban Medicaid coverage of non-abortion care at Planned Parenthood
*ban Medicaid coverage of ANY gender-affirming care (yes, adults)
*block marketplace insurance plans from covering abortion or gender-affirming care

I graduated!

A privilege and fantastic experience to present at DDW this year! I learned so much, from IBD to hep to panc, and saw my favorite people. The best week of the year and I can’t wait until next time! So grateful for the mentorship and encouragement I have and support from programs like the YGS!

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation - Nature Communications Liver fibrosis is a consequence of the sustained inflammatory processes underpinning chronic liver disease. Here authors show that autophagy in CD4 T cells is an important process in preventing the em...

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation🔓
www.nature.com/articles/s41...

Therapeutic benefits of Carica papaya: A review on its pharmacological activities and characterization of papain Carica papaya, commonly referred to as papaya, is a member of the Caricaceae family, boasting a diverse array of compounds and biomolecules, notably p…

Really cool: papaya has an enzyme (papain) that is very effective in treating dry mouth and prevention of associated oral thrush (100% of participants had resolved xerostomia symptoms)

www.sciencedirect.com/science/arti...

Thank you for your kind words!! 😊 i wrote this back in February and it honestly could have an epilogue to it now

Unheard harms to LGBTQ+ patients and scientists There is an old fable about a frog being put into a pot of boiling water. If the frog is placed in gradually warming water, it will not perceive the danger in time and will boil to death. The frog adj...

I wrote (waxing poetic like I do) about the downstream effects and harms caused by attacks on minority health, notably SGM health - so much has changed from writing to publication too

www.thelancet.com/journals/lan...

For people with conditions like IBS and IBD this is extremely tough - having access to restrooms makes public spaces like parks accessible 😔

New content online:

NEW: Per a source with knowledge, the entire HHS Office of Infectious Disease and HIV/AIDS Policy, or OIDP, was just fired.

The only redbud on south campus is in bloom in front of the Micro department 🙂
Unfortunately for those with seasonal allergies, every other tree is in bloom too

Proposed foreign aid cuts could lead to millions of HIV deaths, study estimates A new study shows how cuts to foreign aid could lead to millions of HIV/AIDS deaths and soaring rates of infections, undoing decades of progress against the virus.

www.cbsnews.com/news/foreign...
Lancet HIV journal modeling study estimates that by 2030, there could be between 4.4 million to 10.8 million additional new HIV infections in low- and middle-income countries and 770,000 to 2.9 million HIV-related deaths in children and adults due to foreign aid cuts

Stay safe from online hate with these five tips In this era of anti-science activism, it‘s wise to take steps to protect your research and reputation in the digital realm.

All scientists, regardless of their discipline or location, are potential targets for online hate. But there are things you can do to protect yourself, and resources that can help. Nature provides five steps to get started. #Academicsky 🧪

Lactic acid bacteria and human clinical infection Click on the article title to read more.

LAB are often marketed as “good bacteria” and a drive of some fermented food ‘trends’ (a la, probiotic soda?)
But they can actually cause significant issues - even ‘harmless’ spp like Lactobacillus spp and Leuconostoc

enviromicro-journals.onlinelibrary.wiley.com/doi/pdf/10.1...

Cystic Fibrosis Foundation to fund development of breath test for Pseudomonas infections A breath test would be less invasive than the traditional method of using mucus or phlegm samples from the lungs of CF patients.

Cystic Fibrosis Foundation to fund development of breath test for Pseudomonas infections

A breath test would be less invasive than the traditional method of using mucus or phlegm samples from the lungs of CF patients.

www.cidrap.umn.edu/a...

RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer - Nature In a phase 1 trial, patients with pancreatic ductal adenocarcinoma who were treated with surgery and bespoke neoantigen mRNA vaccines combined with anti-PD-L1 and chemotherapy exhibited marked lo...

The development of extremely successful mRNA vaccines for PDAC is a game changer, a disease with a 86% mortality rate, really sad that this is in limbo now.

www.nature.com/articles/s41...

Decoding microbe–diet–host synergy in colorectal cancer - Nature Microbiology A low-carbohydrate diet or host mismatch-repair deficiency promotes colorectal cancer in synergy with colibactin-producing Escherichia coli, while soluble fibre supplements counteract these effects.

Read our latest News and Views on diet-microbiota-host synergy in colorectal cancer

www.nature.com/articles/s41...

Everything is so awesome and great!

Measles in Oklahoma: 4 cases now

oklahoma.gov/health/healt...

Aberrant bowel movement frequencies coincide with increased microbe-derived blood metabolites associated with reduced organ function - PubMed Bowel movement frequency (BMF) directly impacts the gut microbiota and is linked to diseases like chronic kidney disease or dementia. In particular, prior work has shown that constipation is associate...

A poop a day keeps the doctor for away?

New study indicates lower frequency of bowel movements increases microbially derived uremic toxins . These toxins have been implicated in disease progression and mortality in kidney disease other chronic diseases.

pubmed.ncbi.nlm.nih.gov/39019013/