Holly Fletcher

no paywall

Genomewide study makes ‘quantum leap’ in understanding stuttering Analysis of DNA from 23andMe users points to variants in genes linked to brain function and sense of rhythm

The work represents a “quantum leap” in the field, says Gregory Snyder, a speech scientist at the University of Mississippi who himself stutters. 🧪🧬

www.science.org/content/arti...

Large-scale study uncovers 57 genetic hotspots into stuttering origins Findings published in Nature Genetics point to 48 genes associated with stuttering and highlight neurological pathways of risk.

fascinating and huge study into the origins of stuttering

I've been anxiously awaiting this @natgenet.nature.com piece from @piperbelow.bsky.social to publish!

news.vumc.org/2025/07/28/l...
🧪🧬

there are clips of the researchers talking about the findings and an animated vid w/study highlights

Really excited to share…. I’m joining @wired.com (!) as a senior correspondent covering the business of AI.

I start next Monday, based in SF. If you work in AI, lets grab coffee — get in touch with me via Signal @ kylie.01.

thinking about joining signal to see if i can get on hegseth's distribution chat. i have a little free time i could use to volunteer toward DoD wargames

civic duty, etc

Bluesky’s logo, a trusted verifier’s scalloped checkmark, and a standard verified blue check mark.

We’re introducing a new layer of verification on Bluesky — a user-friendly, easily recognizable blue check.

In addition to account verification issued by Bluesky, we're also introducing Trusted Verifiers. Select independent organizations can verify accounts directly.

USDA cuts hit small farms as Trump showers billions on big farms • Arkansas Advocate Anna Pesek saw a federal program supporting local food purchases as much more than a boost to her Iowa pork and poultry farm.

Cuts to a U.S. Department of Agriculture grant program that allowed schools and food banks to buy fresh products from local farmers is affecting small farms across the country.

Reporting by @stateline.org

Trump's tariffs could increase the cost of an iPhone 16 Pro by almost $300. Who pays for it? Us or Apple?

And if we moved iPhone manufacturing to the U.S.? Let’s just say… get ready for a bajillion-dollar iPhone.

We broke down the bill of materials. www.wsj.com/tech/persona...

How I wrote the notes app of my dreams (no coding required) The new phenomenon known as vibecoding lets you describe an app and have AI build it to your specifications. The results astounded me.

For this week’s Plugged In newsletter, I wrote about using Replit’s AI Agent to vibecode a new note-taking app called Doolee. It’s slick and full of useful features. And for now, at least, it has an audience of one: me. www.fastcompany.com/91309330/vib...

A mosaic of company stock prices with everyone showing red

🚨NEW: NYSE OPENS.

DOW DROPS ANOTHER 1000 PTS

Winning.

TVA to reapply for $800M nuclear funds after Department of Energy removes 'DEI' requirement TVA must resubmit a funding application for its Clinch River nuclear project to focus solely on "technical merit."

TVA to reapply for $800M nuclear funds after Department of Energy removes 'DEI' requirement www.knoxnews.com/story/news/e...

By-the-numbers page from the 2024 annual report that shows the TN ECD's success in 2024 in bringing foreign companies to the state. 51% rural areas, and 3 projects in 'distressed counties' Haywood and Hardeman. Each have vehemently struggled in recent decades and lost hospitals, jobs, workers.

Tennessee governors and biz dev leaders have been on a years-long odyssey to woo foreign investment.

Offering incentives, including training programs to cultivate a workforce in some areas.

Paused, delayed investment from tariffs could be a blow to both urban and rural areas:
2024 TN ECD data

1,000+ foreign companies have invested $47 billion+ in Tennessee and employ >161,900 people, per the TN ECD.

Screengrab from TN ECD shows the top countries with direct investment. France's Macron, today, asked French companies to pause investments
#TNleg #nashville
tnecd.com/advantages/i...

By-the-numbers page from the 2024 annual report that shows the TN ECD's success in 2024 in bringing foreign companies to the state. 51% rural areas, and 3 projects in 'distressed counties' Haywood and Hardeman. Each have vehemently struggled in recent decades and lost hospitals, jobs, workers.

Tennessee governors and biz dev leaders have been on a years-long odyssey to woo foreign investment.

Offering incentives, including training programs to cultivate a workforce in some areas.

Paused, delayed investment from tariffs could be a blow to both urban and rural areas:
2024 TN ECD data

1,000+ foreign companies have invested $47 billion+ in Tennessee and employ >161,900 people, per the TN ECD.

Screengrab from TN ECD shows the top countries with direct investment. France's Macron, today, asked French companies to pause investments
#TNleg #nashville
tnecd.com/advantages/i...

You wouldn't know tariffs are a thing if you only read #Nashville journalism.
NADA on homepages. I checked.

HCA - up
Bridgestone - down
Dollar General - up
Oracle - down
Tractor Supply - up

Writing the reax, forward looking piece article in my head.
Once a biz reporter, always a biz reporter

Goldman Sachs on current state of Republican policy making: “While we continue to think that personal and corporate tax changes that Congress is likely to pass will modestly boost growth, fiscal policy is unlikely to offset the hit from tariffs this year.”

new pharaoh just dropped.

the classic windows xp wallpaper with your friend darth the red panda, a red panda wearing a darth vader outfit and with blue sky butterfly wings, flying above

hello ok i am awake what did i miss
tell me every thing

Three prominent Yale professors depart for Canadian university, citing Trump fears History department power couple Timothy Snyder and Marci Shore and philosophy professor Jason Stanley will begin teaching at the University of Toronto’s renowned Munk School in fall 2025.

yaledailynews.com/blog/2025/03...

75% of US scientists who answered Nature poll consider leaving More than 1,600 readers answered our poll; many said they were looking for jobs in Europe and Canada.

We polled Nature readers to ask if they were thinking of leaving the US for jobs abroad. Three-quarters of them (who said they were US-based scientists) said yes. 🧪

www.nature.com/articles/d41...

Video of the international student at Tufts being arrested by "federal authorities" in Massachusetts has been released and it's terrifying.

They're not even uniformed officers. Just secret police thugs in hoodies and masks.

From WCVB: youtu.be/PuFIs7OkzYY

Screenshot of a single question and answer from interview in the Times Literary Supplement with Ursula K. Le Guin. Here is the quote: If you could make a change to anything you’ve written over the years, what would it be? In The Dispossessed, I would mention the communal pickle barrels at street corners in the big towns, restocked by whoever in the community has made or kept more pickles than they need. I knew about the free pickles all along, but never could fit them into the book.

Ursula K. Le Guin on the true pain of being a writer

In another instance, the Social Security Administration briefly ended a contract that had allowed parents of newborn babies in Maine to sign their children up for a Social Security number at the hospital, instead requiring them to do so in person at an office. Mr. Dudek said he had ordered the move after watching Janet Mills, Maine’s Democratic governor, clash with Mr. Trump at the White House. He quickly reversed that decision, as well as another to end electronic death reporting in the state.

Holy shit: the weirdo running Social Security added administrative burdens to service delivery in Maine after its Governor disagreed with Trump over trans athletes. The idea that public services should be provided consistently and honestly seems beyond them.
www.nytimes.com/2025/03/24/u...

In Pictures: Central Station’s hidden clocks Central Station’s hidden clock tour, a mix of historical and modern clocks.

A "clock wall” was designed to connect the old Sydney Central Station with the new Metro station, "a snapshot of an earlier technology that once ruled people’s lives."

“In a JGPR study of media and govt officials, nearly 37% reported a ‘Greatly Decreased’ interaction rate on X, while an additional 11.7% noted a general decrease. In contrast, only 5.4% of respondents observed an increase in engagement.”

jgpr.net/twitter-surv...

Like she really just sounded like this. All the time.

Understanding every one of Signal’s identifiers We’ve heard some questions about the difference between Signal usernames, phone numbers, profile names, profiles, and nicknames. Let’s talk about it.

Make sure you’re inviting the right person to your Signal group!

To help confirm someone’s identity and keep track of your contacts, @signal.org offers nicknames and information about the groups you share in common with your contacts.

Learn about Signal’s identifiers:

NIH Ends Future Funding to Study the Health Effects of Climate Change It’s unclear whether the guidance will impact active grants, but it appears to halt opportunities for future studies. One climate health expert said the directive would have a “devastating” impact on ...

“We can see with our own eyes how extreme heat and extreme weather are harming people’s health,” said Veena Singla, an adjunct assistant professor at Columbia University’s Mailman School of Public Health.

Judge bars Trump’s EPA from taking back $20B in climate grants — for now The ruling orders EPA and climate change groups to return to court to argue about the fate of the money.

Judge bars Trump’s EPA from taking back $20B in climate grants — for now. "The ruling orders EPA and climate change groups to return to court to argue about the fate of the money."
www.politico.com/news/2025/03...
🔌💡