Dr Stephen T Webb

During the COVID-19 pandemic, variable proportions of agency nurses and higher nurse turnover in pediatric intensive care units were associated with increased complications and ventilator-associated pneumonia.

#CCR25 #MedSky

ja.ma/4jI7YK2

Nope 👎

PROMIZING Discover the impact of Proportional-Assist Ventilation vs. Pressure-Support Ventilation on extubation times in critically ill patients.

PROMIZING

Discover the impact of Proportional-Assist Ventilation vs. Pressure-Support Ventilation on extubation times in critically ill patients.

A graph showing the cumulative probability of successful liberation from ventilation and of death before successful liberation.

In the PROMIZING trial, proportional-assist ventilation with load-adjustable gain factors did not differ significantly from pressure-support ventilation with respect to the time to liberation from mechanical ventilation. Full trial results: nej.md/4kC2a67

@criticalcarereviews.com #CCR25

A graph showing the primary end point, which was death at 96 hours.

Presented at #CCR25:

A trial involving children with severe acute malnutrition and gastroenteritis showed no evidence of a difference in mortality at 96 hours between oral and intravenous rehydration strategies. Full GASTROSAM trial results: nej.md/3TjfSP7

@criticalcarereviews.com

Intravenous Rehydration for Severe Acute Malnutrition with Gastroenteritis | NEJM International recommendations advise against the use of intravenous rehydration therapy in children with severe acute malnutrition because of the concern about fluid overload, but evidence to suppo...

Fantastic presentation of the #GASTROSAM trial at #CCR25 - IV rehydration strategies for children with severe acute malnutrition & gastroenteritis. Amazing commitment to generating evidence in the hardest of circumstances incl a coup and flooding. Bravo! www.nejm.org/doi/full/10....

👑Live from #CCR25 the #Princetrial

🫀Does remote ischemic preconditioning reduce troponin levels after surgery?

A preview on the matter is in #signavitae
🔗 www.signavitae.com/articles/10.22514/sv.2024.151

@giovannilandoni.bsky.social @mmarmiere.bsky.social

#PROMIZINGtrial results are in - no difference in time to successful liberation from mechanical ventilation between proportional-assist ventilation and pressure support ventilation
#CCR25

And… I liked his comment:

“We shouldn’t say Ringer’s Lactate or Hartmann’s or Normal Saline… we should say **Compound Sodium Lactate** and **0.9% Sodium Chloride**”

😄😄👏👏

Myburgh is going deep on the origin of balanced fluid.

Debate continues 200 yrs later.

LR was discovered by accident when tap water containing calcium was accidentally used in a lab experiment, causing greater muscle contractility.

-Dr Myburgh #CCR25

PulmCrit: How to quickly create a useful professional account in BlueSky I discussed the reasons for migrating to BlueSky here. I've received positive feedback from several FOAMed expats who migrated to Bluesky and enjoy it

how to quickly set up a useful MedSky account!

🦋 Mix of basic & more advanced stuff (eg designing user-curated hashtag feeds)

🦋 Take a look & add any useful tips you have in the comments section

blog:

emcrit.org/pulmcrit/blu... #MedSky

🩸#ANHtrial results are live #CCR25

A survey from the authors:
www.signavitae.com/articles/10.22514/sv.2025.076

Figure 2. Oxygen Exposure and Arterial Oxygenation by Treatment Group in Patients With Enhanced Data Collection

Conservative oxygen therapy with a target SpO2 of 90% did not reduce 90-day all-cause mortality compared to usual oxygen therapy in mechanically ventilated adult patients.

#CCR25 @criticalcarereviews.com

https://ja.ma/4kOIA6w

Last trial of day 2

Crystalloid FLUID Choices for Resuscitation of Hospital Patients

Always a hot topic!

#CCR25

Table 3. Clinical Outcomes.

Presented at #CCR25:

In the ANH phase 3 trial involving adult patients undergoing elective cardiac surgery, acute normovolemic hemodilution did not reduce the number of patients receiving allogeneic red-cell transfusion. Full trial results: nej.md/3FxdMrW

@criticalcarereviews.com

Post Image

ICU-acquired weakness and cardiogenic shock in patients requiring mechanical support, highlighting biomarkers and outcomes.

@criticalcarereviews.com #FOAMed #POCUS #FOAMcc #CCR25

https://criticalcarenorthampton.com/2025/06/12/biomarkers-in-icu-acquired-weakness/

A big moment for Royal Papworth Hospital Clinical Trials Unit ! The first RPH trial to be presented at the Critical Care Reviews Conference - Andy Klein CI of the NOTACS Trial presented the results today 👏👏 @criticalcarereviews.com @royalpapworth.bsky.social #CCR25 #NOTACS #NOTACSTrial

Andrew Klein highlights the value of working with patient and family members throughout the lifecycle of a clinical trial #NOTACStrial

#CCR25

Never fails to impress every year… the venue and the conference! 😄👏@criticalcarereviews.com #CCR25

Image shows PDF.

Editorial: The UK-ROX trial demonstrates that targeting lower oxygen saturation in critically ill patients is safe but does not improve outcomes.

#CCR25 @criticalcarereviews.com

https://ja.ma/4ngdtmn

Figure 2. Oxygen Exposure and Arterial Oxygenation by Treatment Group in Patients With Enhanced Data Collection

Conservative oxygen therapy with a target SpO2 of 90% did not reduce 90-day all-cause mortality compared to usual oxygen therapy in mechanically ventilated adult patients.

#CCR25 @criticalcarereviews.com

https://ja.ma/4kG5gWK

A multifaceted anemia prevention and treatment bundle improved hemoglobin recovery up to 3 months after hospital discharge compared to standard care in critically ill adults.

#CCR25 #MedSky

ja.ma/4kGGw0I

Intravenous hydrocortisone was associated with a reduced need for new kidney replacement therapy in patients with septic shock.

#CCR25 #MedSky

ja.ma/3SLC3xg

Figure 2. Total Protein and Calories

Augmenting enteral protein did not improve outcomes for critically ill patients compared with standard protein levels in the intensive care setting.

#CCR25 @criticalcarereviews.com

https://ja.ma/4kuYRxv

Slightly late, and to be updated with the results of today's TTM2 biomarker results, today's Paper of the Day is:

Biomarkers for neuroprognostication after out-of-hospital cardiac arrest

https://criticalcarereviews.com/latest-evidence/paper-of-the-day

Figure 2. Total Protein and Calories

Augmenting enteral protein did not improve outcomes for critically ill patients compared with standard protein levels in the intensive care setting.

#CCR25 @criticalcarereviews.com

https://ja.ma/4mUjFQr

Professor Dan Martin presenting the UK - ROX trial at Critical Care Reviews 2025

Here we go… #UKROXtrial #CCR25

Primary prevention of heart attacks and strokes: seeking consensus on the polypill approach Heart attacks and strokes rise exponentially with age and make a major contribution to increasing healthcare costs and lost productivity. In the UK more than 7 million people are living with cardiovas...

Polypill, Polypill, where art thou Polypill?

www.bmj.com/content/388/...

Demand for fake legs used as a pointer for Cambridgeshire pothole After a pothole gets fixed, others ask to borrow the inverted wooden legs that prompted action.

😁😁

www.bbc.co.uk/news/article...