Diagram of two types of reproduction based on their meiosis. A. shows typical meiosis taking place in individuals with two copies of each chromosome (diploids) resulting in both male and female gametes carrying one copy of each chromosome. Fertilization restores the double copy for each chromosome. B. shows Canina meiosis in individuals carrying five copies of each chromosome (pentaploids) where male gametes only carry one copy of each chromosome and female gametes carry four copies of each chromosome. Fertilization restores the five copy for each chromosome.
Check out the Views & News piece that Joiselle Fernandes and I wrote for @nature.com on the recent work from @amarques.bsky.social and colleagues about one of the most bizarre ways to do meiosis rdcu.be/euabu.
Explained for non-experts!
01.07.2025 10:27 β π 24 π 13 π¬ 0 π 1
1/
π¨ My first PhD preprint is out on bioRxiv!
We show how tiny mutationsβpoint mutations and kb-level indelsβcan shape the massive structure of Arabidopsis centromeres.
π Read it here: doi.org/10.1101/2025...
π§΅ A short thread π
05.06.2025 08:47 β π 6 π 5 π¬ 1 π 2
It's okay the gap penalty score is 0.
13.05.2025 18:33 β π 1 π 0 π¬ 0 π 0
PhDs are paid positions, enough to live comfortably even in a big city like Vienna, and include all health insurance, social benefits, pension contributions. Usually with low to no teaching requirements (but opportunities to get involved if interested!). Main focus is your research.
01.03.2025 08:31 β π 5 π 2 π¬ 2 π 0
Perhaps if helps at this point to outline how the academic path works outside the US. I can speak for Austria, but many EU countries are similar. Students usually do a BSc (3 yrs) then an MSc (2 yrs) then apply for PhD positions (range 3-5 yrs, average around 4).
01.03.2025 08:31 β π 21 π 8 π¬ 1 π 1
I worked in Max-Planck Institute for seven years and loved every day of it. For anyone getting affected by the current changes, I can strongly recommend @maxplanck.de
15.02.2025 10:52 β π 9 π 4 π¬ 0 π 0
@maxplanck.de President @patrick-cramer.bsky.social is on it already.
www.spiegel.de/wissenschaft...
15.02.2025 02:12 β π 38 π 21 π¬ 2 π 4
I would assume that the students and research employees are paid using 85% direct costs. Only the administrative employees would need to be paid from the indirect costs.
09.02.2025 23:06 β π 0 π 0 π¬ 0 π 0
Is it the case that these indirect rates are the major source of funding for the institutions? I would have assumed that they receive separate funding by the government for maintaining the facility which then also controls administrative costs.
08.02.2025 00:40 β π 1 π 1 π¬ 2 π 0
My initial thought (as non american) is that 15% for administration and 85% for direct project related expenses seems to be a good ratio, but I assume I am missing something. I would be happy to know more.
08.02.2025 00:28 β π 1 π 1 π¬ 1 π 0
Credits: FIDE - https://flic.kr/p/2qCjP8a
Congratulations to Koneru Humpy for winning the FIDE Women's World Rapid Chess Championship 2024 - for the second time after 2019! π https://lichess.org/broadcast/fide-world-rapid--blitz-championships-2024--rapid-women/round-11/0eCc1imU/sJNJUFmi
28.12.2024 23:03 β π 48 π 7 π¬ 1 π 0
Other than entangling, could there be other issues that make them not work? π€
20.12.2024 07:31 β π 1 π 0 π¬ 1 π 0
Imo, Faster RAM, better Networking == Redbull for cluster.
25.11.2024 19:07 β π 0 π 0 π¬ 0 π 0
Overview of Bio-xLSTM
Conditional generation of molecules via ICL and 15M parameter model
Generative pre-training of protein language models
Long-context xLSTM models of DNA, proteins, and chemicals.
@smdrnks.bsky.social @phseidl.bsky.social @gklambauer.bsky.social
arxiv.org/abs/2411.04165
20.11.2024 22:11 β π 45 π 10 π¬ 0 π 2
A forerunner in the global landscape of genomics research projects. The study has collected and analysed genome and health data from >500,000 Finnish biobank donors to understand the genetic basis of diseases.
www.finngen.fi
Associate Professor of Bioinformatics at University of Tartu, Estonia. Project lead at eQTL Catalogue. https://kauralasoo.github.io/
News from the Gagneurlab@TUM -- To understand the genetic basis of gene regulation and its implication in diseases.
https://www.cs.cit.tum.de/cmm
Scientist at Illumina using AI methods to interpret the non-coding genome and empower new genetic association discoveries.
Statistical geneticist @ Regeneron
tweets are my own | he/him/his
Weβre working to enable faster and deeper genomic research, to bring genomic healthcare to all who need it.
Treasuring exceptions at IJPB (INRAE Versailles). Thirsty for genetics, chromosome biology and evolution.
The Ensembl project seeks to enable genomic science by providing high-quality, integrated annotation.
Vertebrates: www.ensembl.org
Non-vertebrates: www.ensemblgenomes.org
You can test the new Ensembl browser and share your feedback at beta.ensembl.org
Associate Professor
DFCI & HMS
Plant genetics and epigenetics @ University of Cambridge, Department of Plant Sciences
Plant Omics, Machine Learning, Genomics, Tools, Data Managment
Labs in Forschungszentrum JΓΌlich and HHU DΓΌsseldorf Uni
https://www.fz-juelich.de/en/ibg/ibg-4
https://www.biological-data-science.hhu.de/en/biological-data-science
New here!
Postdoc. Speciation genomics, ecological speciation, experimental evolution and comparative genomics. Dogs!
Research scientist in @Raph_Mercier Lab @mpipz_Cologne, Cell Cycle, Meiotic Recombination, Plant Development, Germ Line Establishment, Genome Stability. Using Genetics, Cytology and Microscopy.
trees, evolution, chromosomes, polyploidy.
Molecular basis of adaptation at @mpipz.bsky.social
Max Planck Institute for Plant Breeding Research - Cologne
π¨π³Professor@HZAUβπ©πͺGL@MPIPZβπΊπΈPD@UofMinnesotaβπ―π΅PhD/MS/BS@HokkaidoU
Plant-microbe interactions
Highly Cited Researcher (ISI Web of Science)
Chinese Government Friendship Award and Chime Bell Award
https://plantimmunity.hzau.edu.cn/
Star Trek, football lover