Mads Gabrielsen

Iain from Research Software Engineering is hosting a webinar on 24th March at 1200!
He will discuss how his team in the SRF supports quality in computational research
To sign up: forms.office.com/pages/respon...

Excited to share our new paper uncovering how FANCD2 recognises various DNA repair proteins www.biorxiv.org/content/10.6... @hw1o9.bsky.social

Integrated Protein Analysis selected Prof Alice Pyne @sheffielduni.bsky.social for Women In Science Day. A UKRI Future Leader Fellow, she develops cutting‑edge AFM technologies revealing DNA structure at sub‑molecular scale.  Her work is reshaping what’s possible in biophysics. #February11

@mgabro.bsky.social from Integrated Protein Analysis facility is hosting a webinar on 24th February at 1200! He will discuss how Integrated Protein Analysis can help you improve your workflows! #QualityAssurance #crystallography #NMR #purification To sign up: forms.office.com/pages/respon...

Another excellent CCP4 workshop has finished. Great talks and an excellent opportunity to catch up with experts in the field. @ccp4mbcx.bsky.social

We were watching that last night. And Gremlins today.

YouTube video by UofG MVLS Integrated Protein Analysis Webinar | Shared Research Facilities at the University of Glasgow

Ever wondered what Integrated Protein Analysis www.gla.ac.uk/colleges/mvl... actually is? Well, wonder no more as here is Mads to explain what it is and how it supports your research: www.youtube.com/watch?v=Ct3a...

The @molecularanalysis.bsky.social Team are hosting a @pacbio.bsky.social launch event for our new #Vega long read instrument, great attendance and fantastic talks from an introduction to the technologies involved, to research taking place already within the University and from further afield!

Poster with an image of a PacBio Vega instrument, and the text: Molecular Analysis; New Technology; PacBio Vega Long Read Sequencing; Genome Assembly: Novel strains CpG methylation Metagenomics: Species and strain resolution Transcriptomics: de novo assembly Differential splicing

We are very excited to offer PacBio Long Read Sequencing in @molecularanalysis.bsky.social !
If you are interested, please get in touch: www.gla.ac.uk/colleges/mvl...
You can also save the date - 14 Nov - as we will be hosting reps from PacBio. More details to follow!

Why would anyone want to be a scientist?

"Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently filled with failure and rejection."

journals.biologists.com/jcs/article/...

Tuning ubiquitin transfer by RING E3 ubiquitin ligases through the linchpin residue RING family ubiquitin ligases (E3s) employ the RING domain to recruit the E2 thioester ubiquitin (E2∼Ub) intermediate to catalyze the transfer of ubiquitin (Ub) to substrates. A cationic Arg linchpin ...

My latest paper has been accepted in @lsajournal.org. Thanks to Mark Nakasone and Lori Buetow for all their efforts. @mvls-srf.bsky.social

doi.org/10.26508/lsa...

Poster for a Protein Production and Purification Workshop, text displayed in a blue circle. Featuring: Construct design for successful purification Overexpression strategies Chromatography with AKTA systems SDS-PAGE & spectrophotometry analysis

Join our hands-on 4-day workshop and master the art of expressing & purifying proteins in E. coli!
Learn:
- Construct design
- Overexpression
- Chromatography
- SDS-PAGE & spectrophotometry
All lab materials provided!
www.gla.ac.uk/colleges/mvl...

Well deserved Evangelos

This is one of the best science fiction /fantasy works I have read. It was like being punched in the guts.

🤩🪩🕺

Very pleased to have been involved with this work, and I think it highlights the power of SAXS when combined with Alphafold predictions. @mvls-srf.bsky.social

It’s too late on a Friday night for me to post sensibly about this work! But I’m super proud of Joanna’s determination to validate Parkin substrates and I love working with her robust and creative science!

Protect transgender scientists | Science
🏳️‍⚧️ :science:

https://www.science.org/doi/10.1126/science.ady0962

This is sure to be a brilliant day, we are looking forward to getting involved!

Interesting webinar for Core Facility folks - advocating for CFs, future-proofing, and navigating impact of outside challenges on the facility.
Join this webinar and opportunity for exchange on June 16th.

Header with images of cultured cells and a Drosophila brain. Text below reads: We are excited to be recruiting our team of 3 post-doctoral research fellows to study the mechanisms underlying ageing-dependent glial cell dysfunction and its effects on neurodegeneration! This is a three-year Medical Research Council-funded cross-disciplinary, multi-partner project with one post-doctoral fellow at each site: Edinburgh Napier, University of Glasgow, and UCL. If you are interested in glial cell biology/neurodegeneration, functional genomics and bioinformatics please get in touch or apply below: Astrocyte ageing & Bioinformatics: Fiona Kerr, ENU (f.kerr@napier.ac.uk): Apply here: Closing Date: https://jobs.napier.ac.uk/mthrprod_webrecruitment/wrd/run/etrec179gf.open?WVID=150547JMmr&LANG=USA Tuesday 24th June 2025 Microglial Ageing & Bioinformatics: Dervis Salih, UCL (dervis.salih@ucl.ac.uk): Apply here: https://www.ucl.ac.uk/work-at-ucl/search-ucl-jobs/details?jobId=35013&jobTitle=Research+Fellow Closing Date: Thursday 26th June 2025 Drosophila models of neurodegeneration: Nathan Woodling, University of Glasgow (nathan.woodling@glasgow.ac.uk): Apply here: https://www.jobs.gla.ac.uk/job/research-associate-49?source=gla.ac.uk Closing Date: Wednesday 25th June 2025

We are excited to be recruiting 3 post-doctoral researchers to study glial cell dysfunction in #agingresearch and #neurodegeneration, including one position using #Drosophila models! If you are interested, please read more below to get in touch or apply (links in thread).

#Science Bluesky, do your thing:
We're organising the International Symposium on Mechanobiology (ISMB) 2026 in #Glasgow & we're looking for research groups in Latin America & Africa who are doing great work in #Mechanobiology or adjacent areas.
Can you indicate some names to me?

Spent the afternoon talking to colleagues from @uofglasgow.bsky.social and @glasgowcaledonian.bsky.social about research strategies.

@lemgruber.bsky.social presenting at the Technical Showcase!

Photograph of people having a conversation about brilliant science at an exhibition table.

Had a great day with @uofgengineering.bsky.social and @uofgchem.bsky.social! Showcasing our technical expertise and having some fantastic conversations! @uofglasgow.bsky.social

Good day at the CoSE / MVLS SRF showcase today

Poster for a Drop-in Clinic with the following information: Friday 30th May 1200-1600 Room 142 (inside Admin office) Wolfson Wohl Cancer Research Centre Garscube campus Discuss your current and future projects. See how the NBIPA can help your research. Let us know what you wish you had access to. Protein production: Advice on construct design Bespoke expression systems Design of purification protocols Access to equipment and columns, including AKTA Micro and LPS free systems Quality assurance: Confirm protein size Confirm protein fold Confirm homogeneity Structural biology: Structural analysis of predictions X-ray crystallography NMR Small-angle X-ray scattering Analytical ultracentrifugation

Got questions about protein production or structural biology?
Swing by the Drop-in Clinic in the WWCRC! Get expert advice on:
- Construct design & purification
- Crystallography, NMR, SAXS & more
📅 Friday 30th May from 1200
@uofgcancersciences.bsky.social @sbohvm.gla.ac.uk @cvrinfo.bsky.social

Poster showing circular lights against a glass ceiling. Poster reads: Technical Showcase Tuesday 27th May. Advanced Research Centre Atrium, 10am - 3pm

We are joining forces with Colleagues from @uofgengineering.bsky.social @uofgchem.bsky.social to present a Technical Showcase! Drop in for a chat, a flash talk or a demo to discover how our technical expertise can support your research!

As always, great work from the Roe lab