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Barcelona Biomedical Genomics Lab

@bbglab.bsky.social

Working on Computational Cancer Genomics. Lead by Núria Lopez-Bigas. www.bbglab.irbbarcelona.org

245 Followers  |  72 Following  |  19 Posts  |  Joined: 22.11.2024  |  2.1751

Latest posts by bbglab.bsky.social on Bluesky

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Delighted and honored to have hosted the 3rd PROMINENT Retreat in Barcelona.
The @cancergrand.bsky.social project led by Allan Balmain, Paul Brennan and Nuria Lopez-Bigas, is progressing thanks to the excellent science being performed by all the teams. Great meeting and best participants!

07.11.2025 14:03 — 👍 5    🔁 3    💬 0    📌 0
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🧪 The #IRBBarcelona #PhD Call is now open! We are offering PhD #fellowships to talented young scientists from around the world who wish to pursue a doctoral degree in #biomedicine!

Learn more and apply now!

General call ➡️ https://bit.ly/3LtzIXi
IRB DRIVE call ➡️ https://bit.ly/4hODx5B

06.11.2025 10:02 — 👍 4    🔁 3    💬 0    📌 1

Interested in doing a #PhD at the #IRBBarcelona? Below is one of the ways you can do so - read for more information!

#computationalbiology #biomedicalscience #biomedicine #biomedical #graduateprogram #research

06.11.2025 10:53 — 👍 1    🔁 1    💬 0    📌 0
PRJ Investigación Biomédica: Nuria López-Bigas
Doctora en Biología por la Universidad de Barcelona. Investigadora ICREA en la Fundació Institut de Recerca Biomédica (IRB Barcelona).Sus campos de especiali... PRJ Investigación Biomédica: Nuria López-Bigas

Dr. @nlbigas.bsky.social, has been awarded the Rei Jaume I Prize in Biomedical Research —one of Spain’s highest scientific honours— for her pioneering work on #cancer mutations & the creation of computational tools to study them.

▶️ https://www.youtube.com/watch?v=OHmrJVtSnqg

@bbglab.bsky.social

04.11.2025 10:03 — 👍 14    🔁 6    💬 0    📌 0
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Don't miss our extraordinary #seminar to be held next week, with @jdegregori.bsky.social, from the University of Colorado Anschutz (@cuanschutz.bsky.social).

Host: Dr. @nlbigas.bsky.social (@bbglab.bsky.social, #IRBBarcelona)

Register here 👉 https://shorturl.at/n74Th

#CancerResearch

🧪

24.10.2025 09:01 — 👍 4    🔁 2    💬 0    📌 0
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Loic Verlingue from Centre Léon Bérard presenting results from the CGI Clinics project at @myesmo.bsky.social #ESMO25 Congress 📢

20.10.2025 11:45 — 👍 1    🔁 1    💬 0    📌 0
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🧪 Out in @nature.com:  Smoking and biological sex shape healthy bladder tissue evolution, offering clues to #cancer risk.

 ✍️ #IRBBarcelona & University of Washington

📌 DOI: 10.1038/s41586-025-09521-x

#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social

15.10.2025 09:03 — 👍 5    🔁 2    💬 0    📌 0
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Un estudi de l’IRB Barcelona relaciona el tabac i el sexe biològic amb el risc de patir càncer de bufeta - Parc Científic de Barcelona Els resultats podrien explicar per què els homes i les persones fumadores tenen un risc més elevat de desenvolupar càncer de bufeta.

#PCBCommunity |🧪 Un estudi de @irbbarcelona.org @bbglab.bsky.social relaciona el tabac i el sexe biològic amb el risc de patir #càncer de bufeta.

👩‍🔬 La recerca, liderada per @nlbigas.bsky.social i Abel Gonzalez-Perez, obre la porta al desenvolupament de noves eines de #prevenció i #detecció precoç.

09.10.2025 10:51 — 👍 6    🔁 3    💬 0    📌 0
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Sex and smoking bias in the selection of somatic mutations in human bladder - Nature Sex bias and association with smoking history identified in the landscape of driver mutations and clonal expansions in normal human bladder tissue may explain the higher bladder cancer risk in men and smokers.

Ultra-sensitive DNA sequencing maps mutations that precede cancer @nature.com @imartincorena.bsky.social
www.nature.com/articles/d41...
www.nature.com/articles/s41...
www.nature.com/articles/s41... @bbglab.bsky.social @irbbarcelona.org @nlbigas.bsky.social

08.10.2025 17:22 — 👍 18    🔁 6    💬 0    📌 0
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🧪 Out in @nature.com:  Smoking and biological sex shape healthy bladder tissue evolution, offering clues to #cancer risk.

 ✍️ #IRBBarcelona & University of Washington

📌 DOI: 10.1038/s41586-025-09521-x

Video credits: 3CatInfo, Som3cat

#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social

09.10.2025 09:03 — 👍 11    🔁 7    💬 0    📌 0
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Sex and smoking bias in the selection of somatic mutations in human bladder - Nature Sex bias and association with smoking history identified in the landscape of driver mutations and clonal expansions in normal human bladder tissue may explain the higher bladder cancer risk in men and smokers.

🚨 New paper alert!

Sex and smoking bias in the selection of somatic mutations in human bladder

www.nature.com/articles/s41...

by @raquelbmi.bsky.social, @ferriol.bsky.social et al (in collaboration with Rosana Risques lab in @uwmedicine.bsky.social)

08.10.2025 16:44 — 👍 67    🔁 29    💬 2    📌 4
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Ferriol Calvet and Raquel Blanco (on the left), PhD students at the @bbglab.bsky.social at #IRBBarcelona, are the first authors of this study.

📝 @nature.com (2025)-DOI: 10.1038/s41586-025-09521-x

#IRBScience #CancerResearch

🧪

08.10.2025 15:00 — 👍 4    🔁 2    💬 0    📌 0
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🗣️ Dr. @nlbigas.bsky.social: “Healthy tissues accumulate many mutations throughout life, but what matters is not only how many there are, but which ones manage to outgrow the others and expand into clones, which are copies of the same cell carrying the same mutations.”

08.10.2025 15:00 — 👍 2    🔁 1    💬 1    📌 0
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Researchers led by Dr. @nlbigas.bsky.social & Dr. Abel González-Pérez at #IRBBarcelona, and Dr. Rosana Risques at the University of Washington, have shown that #smoking and biological sex influence how normal cells evolve in healthy bladder tissue.

08.10.2025 15:00 — 👍 2    🔁 1    💬 1    📌 0
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🧪 Out in @nature.com: Smoking and biological sex shape healthy bladder tissue evolution, offering clues to #cancer risk.

✍️ #IRBBarcelona & University of Washington

➡️ bit.ly/42wcIN5

📌 DOI: 10.1038/s41586-025-09521-x

#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social

🧵👇

08.10.2025 15:00 — 👍 19    🔁 12    💬 2    📌 0
3D-clustering algorithm for cancer driver gene detection – BBGLab

Glad to share our latest paper in our web:

bbglab.irbbarcelona.org/2025/08/3d-c...

25.08.2025 14:50 — 👍 1    🔁 1    💬 0    📌 0
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What is molecular profiling, and how is it reshaping cancer treatment? 🧬

Our latest video explains how analysing the genetic makeup of tumours helps predict treatment response and personalise care for better patient outcomes.

📽️ zenodo.org/records/1584...

22.07.2025 08:02 — 👍 5    🔁 2    💬 0    📌 0
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Oncodrive3D: fast and accurate detection of structural clusters of somatic mutations under positive selection Abstract. Identifying the genes capable of driving tumorigenesis in different tissues is one of the central goals of cancer genomics. Computational methods

New paper from our lab - ‪@bbglab.bsky.social‬.

Oncodrive3D: fast and accurate detection of structural clusters of somatic mutations under positive selection

academic.oup.com/nar/article/...

Kudos to Stefano, Olivia, @fmuinos.bsky.social and Abel

14.08.2025 13:10 — 👍 22    🔁 12    💬 0    📌 0
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🧪 El proyecto internacional PROMINENT, coliderado por la Dra. @nlbigas.bsky.social (@bbglab.bsky.social, #IRBBarcelona), estudia la relación entre tumores primarios y secundarios en pacientes pediátricos.

➡️ https://shorturl.at/WkIR3

#CancerResearch #ContraElCáncer

03.07.2025 09:02 — 👍 9    🔁 3    💬 0    📌 0
🌈 Orgullo LGTBIQ+ en el  @IRBBarcelona  | Celebramos la diversidad en la ciencia
YouTube video by IRB Barcelona 🌈 Orgullo LGTBIQ+ en el @IRBBarcelona | Celebramos la diversidad en la ciencia

At #IRBBarcelona we celebrate #Pride by reaffirming our commitment to #diversity, #equity & #inclusion. Our Pride Info Get-Together united the community to support our #LGBTQIA+ colleagues & embrace every identity. Science thrives when everyone belongs.

Happy Pride! 🌈

youtube.com/shorts/pAZMT...

28.06.2025 09:33 — 👍 10    🔁 4    💬 1    📌 0
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Today our colleague Bet Figuerola @efigbo.bsky.social , presented her work on the genomics analysis of a singular cancer patient at the Node Seminar session of #IRBBarcelona.
Genomics helps us to understand the origins and evolution of cancer contributing to knowledge with possible clinical impact.

25.06.2025 13:12 — 👍 4    🔁 2    💬 0    📌 0
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Back after a few days in Lisbon for the annual #EACR2025 conference! Inspiring and great science. Glad for the opportunity to present our work, coming home with a bunch of new ideas! @bbglab.bsky.social @ferriol.bsky.social

20.06.2025 15:11 — 👍 13    🔁 4    💬 0    📌 0
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Our colleagues Olivia Dove, Raquel Blanco and Ferriol Calvet are attending the #EACR2025. They are sharing their research results with their respective posters and are for sure learning a lot in an excellent Congress with an outstanding list of speakers. @ferriol.bsky.social @raquelbmi.bsky.social

18.06.2025 13:58 — 👍 8    🔁 3    💬 0    📌 0
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Enhorabuena a los premiados en esta edición de los premios Premios Rei Jaume I, especialmente a nuestros dos socios, Núria López-Bigas y José Luis Mascareñas Cid

https://f.mtr.cool/pqizsapqdi

05.06.2025 06:31 — 👍 3    🔁 2    💬 0    📌 0
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Improving access to and the efficacy of personalised medicine is at the heart of the CGI-Clinics project 🧡

💬: Luis Marti-Bonmati at La Fe Health Research Institute

05.06.2025 08:02 — 👍 3    🔁 2    💬 0    📌 0

🏅 The jury of this award, which is one of the most important scientific honours in Spain, highlighted Dr. López-Bigas’s "innovative research on the origin and evolution of cancer mutations and the development of tools to study them."

04.06.2025 11:18 — 👍 2    🔁 2    💬 0    📌 0

We are very proud of our Group Leader, it's a pleasure for all of us to work with you @nlbigas.bsky.social

05.06.2025 08:57 — 👍 5    🔁 2    💬 0    📌 0
Photography of Dr. Núria Lopez-Bigas

Photography of Dr. Núria Lopez-Bigas

Dr. Núria López-Bigas, Head of the Biomedical Genomics lab at #IRBBarcelona and #ICREA Research Professor, has been awarded the prestigious Rei #JaumeI Award in the category of Medical Research.

Congratulations @nlbigas.bsky.social! 🥳

Read the full news here 🔗 tinyurl.com/3abda75b

04.06.2025 11:18 — 👍 20    🔁 3    💬 2    📌 1

Our colleague Olivia Tort @oliviatort.bsky.social interviewed as Scientific Manager:

29.05.2025 14:19 — 👍 1    🔁 0    💬 0    📌 0

@bbglab is following 20 prominent accounts