David Suter

You are finishing your PhD and looking to continue in science?

The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro....

Thanks for reposting!

Useless chart of the month 🥇

Engineering intrinsically disordered regions for guiding genome navigation Intrinsically disordered regions (IDRs) navigate transcription factors (TFs) to their binding sites in genomes, raising the question of how IDR sequen…

Beautiful and intriguing piece of work on the role of hydrophobic residues in IDRs in guiding TFs to their binding sites
www.sciencedirect.com/science/arti...

Together they reveal a rule:
biophysics and partnership entwine—
speed and specificity, co-written in the search.

Big thanks to co-authors Cédric Deluz and Louise Font, as well as to the flow cytometry (FCCF) and genomics (GECF) core facilities of EPFL

In the crowded nucleus,
SOX2 and ESRRB wander DNA-
seeking their precise words

When hydrophobic pull grows strong,
they linger in tight embraces,
yet miss their true genomic homes

Extra negative charge dims weak whispers;
ESRRB loses its way without SOX2,
drifting toward borrowed binding grounds

📢 New preprint from the lab by super-talented postdoc Ludovica Vanzan www.biorxiv.org/cgi/content/... - thread 👇

Journal X: 👊 you have two weeks max to submit your final revisions !
> 3 weeks after submission: ms status = "submitted"
🫥

Y-axis label 😱

I miss these pieces so much...sigh...

Congratulations Fiona, this is fantastic news ! You telling me the story of your lab about neurogenesis in pregnant mice was the big highlight of my 2024 visit at the Biozentrum

Many congrats to the two 2026 laureates of the Jeantet Prizes!👏💐

Start your independent as an ELISIR fellow right after your PhD, in one of the most terrific places in Europe !

And here the EPFL news actu.epfl.ch/news/how-cel...

Thank you for your kind words Manuel, and Merry Christmas !

Big shout out to all co-authors involved, as well as to EPFL bioimaging, proteomics, genomics and flow cytometry core facilities for their fantastic help on this project.

As a consequence proteome is virtually unperturbed even after strong reduction of their protein synthesis rate ! Speculation: might contribute to the resilience of the blastocyst to fluctuating/harsh nutrient conditions of oviduct.

We describe passive adaptation as a general mechanism adapting protein degradation rates to change in protein synthesis. Naïve ES cells leverage a 2nd, mTOR-dependent mechanism to reach perfect adaptation 💪.

Happy holiday ❄️⛄🎅! Global protein synthesis rates can fluctuate dramatically as a function of food intake, infections, energy resources, etc. Wondering whether/how protein elimination routes adapt to these changes to maintain proteome homeostasis ? Find out here: www.cell.com/cell-systems....

Your ability to cope with this with such grace forces admiration 🙂👏

Things are going great over at X, The Everything App

Remind me, how much money does Cell pay reviewers to deal with this ?

YouTube video by BBC Sounds Are we living through the fall of civilisation? | The Reith Lectures 2025

My first Reith Lecture is now out in video form: A Time of Monsters.

On moral decay, elite cowardice, and why we need a moral revolution. Watch here 👉 youtube.com/watch?v=fUJ-...

(With one tiny edit at 4:28, for those who notice such things 😉)

📢 Open position alert: the Institute of Bioengineering of EPFL is looking for a new IBI manager ➡️ careers.epfl.ch/job/Lausanne...

I think one of the reasons is the soaring complexity of papers with exponential rise in numbers of panels per figure and numbers of supplementary figures, can feel quite discouraging sometimes

YouTube video by David Suter Chopin, Ballade no 4 opus 52 - my recording at home

Sharing a recording I just made at home, Chopin Ballade 4 - seems to me there is endless work to do on this complex piece, opinions/suggestions most welcome www.youtube.com/watch?v=gu5m...

Et donc le lien avec l'alimentation ne tient de toute façon pas vraiment pour "expliquer" l'espérance de vie de 30-40 ans

Vous avez raison - mais une fois passé le cap de la mortalité infantile très élevée, il semble qu'ils vivaient 60-70 ans - et donc ce nombre de 30-40 ans n'est pas vraiment informatif - en gros soit on mourrait dans la période infantile, soit souvent bien plus tard que 30-40 ans.

Maintenant je concède volontiers qu’on fait quand même mieux aujourd’hui… Et probablement pas à cause du sans gluten et du bio 🙃

Eh non c’est pas vrai, mourrait plutôt vers 60 ou 70 ans

Et après les avoir battus au Judo aux J.O. l'an passé...