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Nils Blüthgen

@molsysbio.bsky.social

Charité and Humboldt University Berlin, Computational Modelling, Cancer, Signaling

1,089 Followers  |  837 Following  |  81 Posts  |  Joined: 22.09.2023
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Posts by Nils Blüthgen (@molsysbio.bsky.social)

Toll, dass die Berliner Behörden jetzt verstanden haben, wie Cell Broadcast grundsätzlich funktioniert, jetzt vielleicht noch ne Schulung zum sinnvollen Einsatz, danke.

07.01.2026 21:06 — 👍 572    🔁 61    💬 4    📌 7
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Zell- & Molekularbiologin Kerstin Kaufmann wird Einstein-Prof & bleibt an der @humboldtuni.bsky.social! Durch Koops mit BIMSB, @mpi-mp-potsdam.bsky.social & @igzleibniz.bsky.social vernetzt sie Molekularbiologie, quantitative Modellierung & Bioengineering.
www.einsteinfoundation.de/presse/2026/...

07.01.2026 11:02 — 👍 5    🔁 1    💬 0    📌 1
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Fig. 6: Mathematical model

29.11.2025 08:13 — 👍 107    🔁 12    💬 2    📌 3
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Offener Brief an die Bundestagsfraktionen von CDU/CSU, SPD, Bündnis 90/Die Grünen und Die Linke zur Rückkehr der grundsätzlichen Öffentlichkeit der Sitzungen des Forschungsausschusses An die Vorsitzenden der Bundestagsfraktionen von CDU/CSU, SPD, Bündnis 90/Die Grünen und Die Linke Berlin, 19.11.2025 Öffentlichkeit im Bundestagsausschuss für Forschung, Technologie, Raumfahrt und T...

Der #Forschungsausschuss des Bundestags tagt nicht mehr öffentlich — das war’s dann mit Tranzparenz wissenschaftspolitischen Handelns auf Bundesebene! Erschwert die Arbeit von Journalist_innen ebenso wie unsere für #IchBinHanna uvm. massiv. @wpk.bsky.social fordert in 1 offenen Brief, das zu ändern:

21.11.2025 15:45 — 👍 120    🔁 50    💬 1    📌 5
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Charité-Chef Heyo Kroemer über Kürzungsfolgen: „Bei keinem Uniklinikum in Deutschland wird derart gespart“ 56 Millionen Euro weniger Zuschüsse bekomme das Berliner Uniklinikum 2026, sagt Charité-Chef Kroemer. Das wird sich auf Berlins medizinische Versorgung auswirken – und könnte die Spitzenstellung in de...

Die Charité-Chefs haben am Montag im Berliner Wissenschaftsausschuss die Folgen der Kürzungen für die Uniklinik skizziert. "Drittmittel werden sinken, Ambulanzen müssen schließen“, fasste Dekan Joachim Spranger es zusammen. (T+) www.tagesspiegel.de/wissen/chari...

19.11.2025 17:09 — 👍 26    🔁 11    💬 0    📌 1
Bill from DM

Bill from DM

Welcome our new colleagues: Prof. Flasche aus Ede and Prof. Geschirrschwämme! Looking forward to working with you!

17.11.2025 08:27 — 👍 5    🔁 0    💬 0    📌 0

Yeah!

16.11.2025 07:00 — 👍 0    🔁 0    💬 0    📌 0

Aim high 🚜 !

15.11.2025 20:54 — 👍 0    🔁 0    💬 0    📌 0

Finally! 🚜

15.11.2025 20:31 — 👍 0    🔁 0    💬 0    📌 0
Email: Dear Nils Blüthgen,
Cureus Journals, a part of Springer Nature, will be launching its fourth open access journal—Cureus Journal of Agriculture and Food Science (CJAF)— in December 2025. 
 
I would like to take this opportunity to invite you to apply for a position on our esteemed Editorial Board as an Associate Editor (AE) for CJAF.

Email: Dear Nils Blüthgen, Cureus Journals, a part of Springer Nature, will be launching its fourth open access journal—Cureus Journal of Agriculture and Food Science (CJAF)— in December 2025. I would like to take this opportunity to invite you to apply for a position on our esteemed Editorial Board as an Associate Editor (AE) for CJAF.

I always wanted to join the editorial board for an agricultural journal. Clearly my expertise. Will be a great journal 🤡
#scientificspam

15.11.2025 20:19 — 👍 7    🔁 0    💬 5    📌 0
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Senat will 12,5 Millionen Euro investieren: NFL kommt 2025 für ein Spiel nach Berlin Die nordamerikanische Football-Liga NFL wird 2025 ein Spiel in Berlin austragen. Bis 2029 könnten zwei weitere Folgen. Die Kosten dafür sind hoch. Das Land muss trotz Haushaltskrise Millionen investie...

Berlin’s senate invests >12 mio EUR for 3 NFL games in Berlin, at a time where they cut millions at the universities that are already underfunded, with collapsing buildings. They definitely seems to have priorities that are not mine.
www.tagesspiegel.de/berlin/senat...

06.11.2025 19:49 — 👍 15    🔁 5    💬 2    📌 0
Email: Hi Professor Nils Blüthgen,

My name is xxx yyy, I am a PhD student passionate about economics and entrepreneurship. I came across your work “Quantitative modeling of signaling in aggressive B cell lymphoma unveils conserved core network”, a piece that truly stands out for its precision and contribution to society in the field of finance.

Email: Hi Professor Nils Blüthgen, My name is xxx yyy, I am a PhD student passionate about economics and entrepreneurship. I came across your work “Quantitative modeling of signaling in aggressive B cell lymphoma unveils conserved core network”, a piece that truly stands out for its precision and contribution to society in the field of finance.

“Stands out … for its contribution to the society in the field to finance”???? Maybe the most bizarre spam email I ever received…

06.11.2025 12:28 — 👍 3    🔁 1    💬 0    📌 0
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Reporter CRISPR screens decipher cis-regulatory and trans-regulatory principles at the Xist locus - Nature Structural & Molecular Biology Here Schwämmle et al. develop CRISPR reporter screens to map transcription-factor-regulatory element interactions at the Xist locus, revealing a two-step mechanism integrating developmental and X-dosage signals to initiate X-chromosome inactivation.

⚠️ Paper alert: Using a novel CRISPR screening approach, we mapped the entire regulatory network controlling Xist—key for X-chromosome inactivation.
👉 We discover how sex and development signals are decoded at a single gene locus.
www.nature.com/articles/s41...
👇 Bluetorial

06.10.2025 13:01 — 👍 111    🔁 50    💬 3    📌 2
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a cartoon of donald trump with the words be prepared above him ALT: a cartoon of donald trump with the words be prepared above him

When I was at NIH and shutdowns loomed, it was discovered that the administration was planning to shut down PubMed. The head of NCBI called the powers that be and pointed out that this would threaten patient safety

Who knows what will happen now

Just in case, remember Euruope-PMC
(europepmc.org )

29.09.2025 13:34 — 👍 169    🔁 90    💬 8    📌 10
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Wissenschaftliche Resilienz: Auf dem Weg aus der PubMed-Abhängigkeit – Deutsches Ärzteblatt

The Ärzteblatt asked me about the instability of Pubmed (Why my? Don't know...). Not sure if I agree with the colleagues that we should build up national resources, I rather think we should strengthen existing European ones (e.g. EuropePMC, ENA, EGA...)... www.aerzteblatt.de/archiv/wisse...

04.10.2025 11:27 — 👍 8    🔁 0    💬 0    📌 0
Nicky McGranahan

Nicky McGranahan

Nicky McGranahan kicking off the last day showing the evolutionary history of metastasis. Amazing data and analysis.

26.09.2025 09:54 — 👍 2    🔁 1    💬 0    📌 0
Students discussing at poster

Students discussing at poster

Impression of the poster session at bimsb, showing the staircase

Impression of the poster session at bimsb, showing the staircase

Students discussing at poster

Students discussing at poster

Very dynamic poster sessions at the late summer school on tumor heterogeneity and treatment followed by a rooftop party. Thank you @mdc-bimsb.bsky.social for hosting us!

26.09.2025 07:32 — 👍 4    🔁 2    💬 1    📌 0
Tancredi Massimo

Tancredi Massimo

Adila Apsara

Adila Apsara

Siddharth Annaldasula

Siddharth Annaldasula

Great talks from PhD students Tancredi Massimo Pentimalli, Adila Apsara: and Siddharth Annaldasula!

25.09.2025 09:27 — 👍 3    🔁 1    💬 1    📌 0
Efrat Shema

Efrat Shema

Efrat Shema kicking off today’s program with a lecture on epigenetics and single cell methods.

25.09.2025 09:23 — 👍 4    🔁 1    💬 0    📌 0
Finja Becker introducing Sven Nelander

Finja Becker introducing Sven Nelander

Final session for today: Sven Nelander discusses how patient specific models combined with advanced molecular biology and large scale computation allow for a better understanding of CNS cancers.

24.09.2025 14:01 — 👍 2    🔁 1    💬 1    📌 0
Ido Amit

Ido Amit

Anton Henssen

Anton Henssen

We continue with Ido Amit who shows how single cell approaches allow to improve immune therapy and Anton Henssen introducing us to the world of extrachromosomal DNA and how this relates to tumor heterogeneity. Fascinating!

24.09.2025 13:48 — 👍 3    🔁 2    💬 1    📌 1
Ulrich Keilholz

Ulrich Keilholz

Heiko Enderling

Heiko Enderling

First session: Uli Keilholz of the comprehensive cancer center on how complex data and models are now used in the clinics, and Heiko Enderling on modeling approaches. Both show excellent examples on how computation already now is impotent for clinical decisions, and how it will be in future.

24.09.2025 08:56 — 👍 4    🔁 1    💬 1    📌 0
Foto of the kickoff and welcome.

Foto of the kickoff and welcome.

Kicking off today’s Late Summer School on tumor heterogeneity and treatment resistance with an amazing program. Great to see a huge turnout!

24.09.2025 08:50 — 👍 2    🔁 1    💬 0    📌 0
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Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome UPF1 depletion inhibits nonsense-mediated mRNA decay (NMD) and stabilizes direct target transcripts within hours. Boehm et al. use conditional protein degradation and advanced transcriptomics to map t...

Very harmonious and inspiring collaboration with Niels Gehring, @volkerboehm.bsky.social and team at Uni Köln, and colleagues at @mdc-berlin.bsky.social . Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome: Molecular Cell www.cell.com/molecular-ce...

12.09.2025 07:26 — 👍 30    🔁 11    💬 1    📌 1
Poster of CompCancer Seminar Series

Poster of CompCancer Seminar Series

Join us for our first CompCancer seminar this fall on Thursday, 4pm with Chris Sander (Harvard): „Catch Cancer Early with the Help of AI Tools“. Maud Menten Room, House 18, Campus Nord HU

08.09.2025 19:12 — 👍 4    🔁 1    💬 0    📌 0
Beim Spatenstich (v.l.n.r.): Dr. Ina Czyborra, Senatorin für Wissenschaft, Gesundheit und Pflege, Prof. Dr. Julia von Blumenthal, Präsidentin der Humboldt-Universität zu Berlin, Christian Gaebler, Senator für Stadtentwicklung, Bauen und Wohnen und Prof. Dr. Heyo K. Kroemer, Vorstandsvorsitzender Charité - Universitätsmedizin Berlin. Foto: Stefan Klenke

Beim Spatenstich (v.l.n.r.): Dr. Ina Czyborra, Senatorin für Wissenschaft, Gesundheit und Pflege, Prof. Dr. Julia von Blumenthal, Präsidentin der Humboldt-Universität zu Berlin, Christian Gaebler, Senator für Stadtentwicklung, Bauen und Wohnen und Prof. Dr. Heyo K. Kroemer, Vorstandsvorsitzender Charité - Universitätsmedizin Berlin. Foto: Stefan Klenke

Spatenstich für den Forschungsneubau Optobiologie an der #HumboldtUni. Gemeinsam mit der Charité und der @berlinualliance.bsky.social entsteht ein Zentrum für interdisziplinäre Spitzenforschung. Auf rund 3.800 m² entstehen Laborflächen für 110 Wissenschaftler*innen 👉 www.hu-berlin.de/de/pr/nachri...

26.08.2025 13:14 — 👍 6    🔁 2    💬 0    📌 1

Why do kids respond differently to a new virus than adults? Lev has the answer… it is differences in Stat signaling. Happy that we (mainly @astaburuaga-garcia.bsky.social ) could contribute a bit. Congratulations @sawitzkilab.bsky.social and @woodenrobo.bsky.social to this great paper!

19.08.2025 19:51 — 👍 9    🔁 1    💬 0    📌 0
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Ben-Zion Shilo (1951–2025) Ben-Zion Shilo, a distinguished Israeli geneticist (Figure 1), passed away this April at the age of 73 at his home in Rehovot. Benny, as he was known to his friends and colleagues around the world, ma...

Very moving obituary by Stas Svartsman for Benny Shilo. I met Benny a few years ago at the WiKo in Berlin and enjoyed our very inspiring conversations about signaling dynamics and patterning. Glad that I met him.

www.cell.com/developmenta...

19.08.2025 19:46 — 👍 3    🔁 0    💬 0    📌 0
19.08.2025 16:56 — 👍 3    🔁 1    💬 0    📌 0
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Rewired type I IFN signaling is linked to age-dependent differences in COVID-19 Petrov et al. identify an age-dependent shift in interferon signaling during SARS-CoV-2 infection, with older individuals favoring a STAT3-driven inflammatory response. This mechanistic insight helps ...

Excited to share our new study on how age-related changes in STAT signaling impact antiviral responses and hyperinflammation in COVID-19!

🧵 Explainer thread by the first author Lev Petrov linked below ⬇️

19.08.2025 16:56 — 👍 10    🔁 2    💬 1    📌 1