Philippa Matthews

#MASLD and #HBV overlap tackled in this article - lots of questions remaining in how to assess and treat this emerging dual threat to global #liver health 🧪
#MedSKy #LiverSky #HepSky #hepatitis
hepatologyforum.org/article/257

Excellent work led by Ricky Sinharay showing cost-effectiveness of expanding #HBV treatment, which supports scale-up to reduce complications & mortality 🧪
@england.nhs.uk @royalberkshospital.bsky.social @easlnews.bsky.social @who.int
#LiverSky #MedSky #hepatitis #BASL
fg.bmj.com/content/earl...

British Association for Study of the #Liver discussion on #treatment & #cancer #surveillance for people living with #HBV - we should treat all who need surveillance, but surveillance not necessary for all on treatment. Important to unify clinical & public health approaches. 🧪 #BASL #BVHG #LiverSky

Emily's fundraiser for Museum of Homelessness Help Emily Martyn raise money to support Museum of Homelessness

Brilliant that @emilymartyn.bsky.social is running the #LondonMarathon & fundraising for the #Museum of #Homelessness which tells stories & changes lives of people living with complex challenges. A privilege to support a cause close to my ❤️ @ourmoh.bsky.social

www.justgiving.com/page/emily-m...

Guinea-Bissau stops vaccine study funded by Trump administration Guinea-Bissau's foreign minister has said his government has stopped a study funded by the Trump administration aiming to evaluate side effects of the life-saving hepatitis B vaccine, including any li...

Story time:
The CDC (Kennedy) gave $1.6m to fund an unethical Hep B trial in Guinea-Bissau. WHO/scientists denounced it.

Enter @standupforscience.bsky.social. They briefed congress on this study. It is now cancelled.

Science activism is essential right now.
🧪 www.reuters.com/business/hea...

Grateful to see Ana Puentes at @elpais.com spotlight our commentary on US funding cuts and their impact on viral hepatitis elimination.

Visibility and public engagement are essential — especially right now.

elpais.com/planeta-futu...

Voices from the frontline: how global funding cuts are reshaping the viral hepatitis response Hepatitis B virus (HBV) and hepatitis C virus (HCV) are among the world's leading infectious threats, together responsible for over a million deaths each year, but these infections remain neglected by...

Lots of focus on the impact of #funding cuts on #HIV but there are wider repercussions.
Here we report 'Voices from the frontline: how global funding cuts are reshaping the viral #hepatitis response' 🧪
@lancetgastrohep.bsky.social @worldhepalliance.bsky.social
www.thelancet.com/journals/lan...

Collage of pictures showing our team activities in clinic, comms and education

Collage of pictures showing our team building activities and meetings

Collage of photos showing team members in the UK, South Africa and Ghana

Proud to be part of this inspiring team delivering #research & implementation for #hepatitisB #HBV in the lab, in #clinic and for #PublicHealth across disciplines & continents.
#WomenInSTEM #STEM #science #MedSky
🧪 @crick.ac.uk @ahri-news.bsky.social
#InternationalDayofWomenAndGirlsinScience

Great that #liver #cancer is included in the new National Cancer Plan.
➡️ Only 13% survive 5 years
➡️ >50% higher incidence in the most deprived areas
➡️ Complex treatment needs, due to underlying liver conditions

@britishlivertrust.bsky.social
🧪 #MedSky

britishlivertrust.org.uk/the-national...

This makes me feel ill… but not surprised. And a sense of despair that we’re only just scratching the surface of a dangerous, abusive, toxic culture that permeates politics, industry, education, science, religion, finance, healthcare. Even the things we thought might be motivated for good.

We Do Care | NEJM Physicians throughout Minnesota bear witness to the devastation that U.S. Immigration and Customs Enforcement is wreaking. They implore physicians everywhere to raise their voices.

I strongly encourage everyone to read these two pages from Bernard E. Trappy, M.D., for Minnesota Physician Voices.

In brief, this NEJM article describes #physicians' observations and experiences in the wake of ICE's occupation and mass operations in Minnesota.

www.nejm.org/doi/pdf/10.1...
(1/5) 🧪

A protocol for 'MoLo' #liver #health project for the #Mongolian community in #London is now on line: a template for combining #education, healthcare & #research.
wellcomeopenresearch.org/articles/11-72

#HBV #HIV #LiverSky #IDSky #MedSky 🧪
@crick.ac.uk @uclnews.bsky.social @emilymartyn.bsky.social

Our preprint addresses therapeutic drug monitoring for #HBV #hepatitisB. It may sound niche, but is a huge clinical & research gap. Better understanding could inform better #treatment & improve outcomes. 🧪💊
#LiverSky #MedSky #IDSky #Pharmacology #TDM #tenofovir
www.researchsquare.com/article/rs-8...

And big thanks to our funders, advisors and partners: @ukhsa.bsky.social @britishlivertrust.bsky.social @uclhresearch.bsky.social @uclh.bsky.social
@crick.ac.uk
#MongolianCommunityOrganisation #OnomFoundation

These events show the success of #decentralisation, community #codesign, #multidisciplinary approach, with interpreters and #PeerSupport to provide #diagnosis and #treatment for #liver disease and #hepatitis.
Well done @emilymartyn.bsky.social for coordinating this logistical feat!

MoLo project team photo by the University College London inclusion health outreach van with the Mongolian Community Organisation hosting the project.

Team members set up in advance for point of care testing

Kit for point of care testing for HIV, HBV, HCV and syphilis

Our #liver #health project ‘MoLo’ for the #Mongolian Community in #London: #education, assessment for #diabetes, metabolic liver disease #MASLD, #HIV & viral #hepatitis, & linkage to care. Huge team effort with brilliant engagement.
@who.int @crick.ac.uk @ucl.ac.uk
#HBV #HCV #LiverSky #MedSky
🧪🇲🇳

A #trial that involves withdrawing a lifesaving #vaccine (backed by decades of safety data) in a low income, high prevalence setting?
Over 1000 new #HBV infections predicted as a result.
Flawed endpoints.
No ethics oversight.
Exploitative, corrupt malpractice.
#LiverSky #MedSky #CDC @gavi.org
🧪

The #preprint movement has changed the academic ecosystem for the better: wider dissemination, community review, democratisation of access.
Brave, disruptive & pioneering 🙌🏽🧪
Thank you
@richardsever.bsky.social
@johninglis.bsky.social
@biorxivpreprint.bsky.social @medrxivpreprint.bsky.social

Interesting to see this from #GSK... but lots of questions that still need answering (especially 'please can we see the data?'). Noting functional cure is still attained for a minority with #Bepi, and only when taken on top of standard of care #therapy with NA agents. #MedSky #LiverSky #HBV #NoHep 🧪

I'm persevering here @bsky.app ...I like the format, but not close to the engagement I had on X/Twitter for #science comms, & lots of the old community ( #MedSky #LiverSky #PublicHealth #GlobalHealth) haven't made the jump. Many institutes & organisations missing. Now more action on @linkedin.com.

Happy new year!

We describe #HBV infection in #Uganda, to determine #treatment eligibility. #Liver assessment by #fibroscan important to determine who should be treated.
Some drug resistance motifs seen in the context of #HIV.
@who.int @crick.ac.uk @ndm.ox.ac.uk #LSHTM #UVRI #MedSky
🇺🇬 🧪
doi.org/10.1016/j.ji...

Strengthening hepatitis B virus clinical research in Africa: the need for multistakeholder collaboration, funding, and political will Africa bears a disproportionate burden of hepatitis B virus (HBV) infection, with 68 million chronically infected individuals and 65% of global new in…

Strengthening clinical, translational, implementation #research in #Africa for the #elimination of viral #hepatitis is an urgent #PublicHealth priority.
We have the tools, but the field has been neglected.
🧪 #HBV #MedSky
@lancetmicrobe.bsky.social @who.int
www.sciencedirect.com/science/arti...

Micro-elimination of Hepatitis C virus (HCV) infection in the General Population Cohort in rural Uganda: Long-term follow-up to assess feasibility and outcomes of a screening and treatment interventio... The availability of highly effective curative direct acting antiviral (DAA) therapy for hepatitis C virus (HCV) is a cornerstone of elimination strate…

#HepatitisC #HCV has been neglected in #Africa but affordable pangenotypic #DAA #treatment, community engagement & #decentralisation offer improved prospects.
We report a #microelimination programme in #Uganda.
@ndm.ox.ac.uk @crick.ac.uk @who.int
🧪🇺🇬🌍💊 #MedSky
www.sciencedirect.com/science/arti...

@decappeal.bsky.social
dec.org.uk

US vaccine panel votes to end universal hepatitis B vaccination for newborns Trump, who called the decision

Dangerous retrograde step as #US #CDC pulls back on recommendations for #HBV #vaccine at #birth & dilutes advice for a proper three dose #immunisation schedule.
This is a safe, cheap, robust & well-evidenced vaccine.
There is no evidence of harm. 🧪
@who.int @gavi.org
www.bbc.co.uk/news/article...

Picture of mug with big text Vaccines cause adults’

It’s a crucial moment to say this again, loudly:
#vaccines cause adults.
Let’s keep causing adults.

🧪 #HBV #NoHep #vaccineswork #MedSky #HepSky #IDSky #PublicHealth @who.int
@gavi.org @altcdc.altgov.info @worldhepalliance.bsky.social

If timely birth dose #HBV #vaccine is restricted, there will be a predictable surge in new chronic infections.
There are *no* documented harms of this vaccine dose in early life.
In contrast, chronic viral #hepatitis leads to *over a million deaths a year worldwide*.
#vaccineswork
#MedSky 🧪💉

Make the wrong decisions for #vaccines & ‘preventable diseases can come roaring back’.
A timely dose of #HBV vaccine at birth is one of our simplest, safest & best anti #cancer strategies.
Universal access matters.
Look at the figure below- a stunning success since roll-out.
@gavi.org
#MedSky 🧪

Conversation and next steps definitely to be continued (not sure the Crick cafe will stretch to cocktails…? but we can tempt visitors with coffee and science instead ☕️🧬🧪🩺). Look forward to welcoming you back in 2026.