New preprint alert! Very proud of this work, lots of hard work that turned into a really cool story!
This was my first chance to step into a senior role, but most importantly, it means far more to me than just the science.
You should always say yes to new projects.
www.biorxiv.org/content/10.6...
A Goldilocks zone of DNA flexibility defines stable yet plastic nucleosomes, tuned by histone chemistry https://www.biorxiv.org/content/10.64898/2026.02.16.706184v1
18.02.2026 15:48 — 👍 6 🔁 4 💬 0 📌 0
How do DNA sequence and histone chemistry tune nucleosome stability and plasticity?
Check out our latest work to find out. Now available on bioRxiv!
www.biorxiv.org/content/10.6...
@juliamaristany.bsky.social
@janhuemar.bsky.social
@rcollepardo.bsky.social
Share with your colleagues!!
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Our Science paper is out!
Huge congratulations to @huabin-zhou.bsky.social, Mike Rosen, and the brilliant @janhuemar.bsky.social @juliamaristany.bsky.social and @kieran-russell.bsky.social from our group
News: bit.ly/4avnkAr and bit.ly/3XBGVHS
Great perspective by @vram142.bsky.social +K Zhang
A rendering of multiple Oct4 molecules bound to a chromatin fibre
🚨 🚨 🚨 New preprint alert!!! 🚨 🚨 🚨
In the past, we have learnt that Oct4 can induce nucleosome breathing on the mono-nucleosome level.
But what happens when you have a fibre of multiple nucleosomes?
www.biorxiv.org/content/10.1...
@rcollepardo.bsky.social @juliamaristany.bsky.social
🚨 TLM Cambridge Online Seminar - 14.05.25 | 16:00 UK
Alessandra Villa & Berk Hess (KTH) : "Enhance simulation sampling using GROMACS"
Please repost & to attend online please register to our 📧for the zoom link: lists.cam.ac.uk/sympa/subscr...
To close, we have Jan Huertas from Cambridge University @janhuemar.bsky.social presenting our work in collaboration with the Rosen lab on the structure of chromatin inside condensates and the role of histone tails #BPS2025 @mgo-bps.bsky.social
16.02.2025 00:57 — 👍 8 🔁 2 💬 0 📌 0