Centre for Integrative Biology

Mechanical forces shape the developing brain 🧠💥 Compression from high cell density doesn’t just squeeze cells - it compromises mitotic fidelity! New preprint on how mechanics impact neural development from Veronique Marthiens & co-authors @institutcurie.bsky.social @cbitoulouse.bsky.social
🧠🔧👇

RNA Pol II-based regulations of chromosome folding How transcription and cohesin complexes interact to regulate 3D genome organization remains unclear. Chapard et al. dissect their respective contributions and their interplay in shaping the genome arc...

Pleased to see this study out, combining experimental work from our lab at the @cbitoulouse.bsky.social, in particular by @nathaliebastie.bsky.social and @beckof.bsky.social, and from Laura Chaptal and @alengronne.bsky.social at IGH Montpellier
@cnrs.fr @cnrsbiologie.bsky.social

Congrats to all!

HP1, une protéine architecte déchue au cours de l’évolution Dans un article publié dans la revue Nature Communications, des scientifiques ont étudié une protéine, appelée HP1, q

#ResultatScientifique🔎| HP1, une protéine architecte déchue au cours de l’évolution

🤝 @cnrs.fr @cbitoulouse.bsky.social
✍️ Fabian Erdel
📕 @narjournal.bsky.social | buff.ly/aimHSLW
buff.ly/1Bc1GQt

#ResultatScientifique🔎| Le stress aide les poissons à renforcer leur intelligence collective et à s’adapter plus vite aux changements 🐟
🤝 @cnrs.fr @cbitoulouse.bsky.social
✍️ Guy Theraulaz et Clément Sire
📕 @prxlife.bsky.social | buff.ly/m9Anxxe

Check out @julielebris.bsky.social’s thread on our latest manuscript describing phenotypic heterogeneity in capsule production in Klebsiella & Acinetobacter @klebclub.bsky.social

This work started when I was still in @pasteur.fr & got finished in @cbitoulouse.bsky.social
#microsky #phagesky

📢 J-15 avant la fin de notre appel à projets de recherche sur Alzheimer 🧠
🔬Postuler ici : alzprojects.org/register?vie...
@unistra.fr
@inp-marseille.bsky.social
@cbitoulouse.bsky.social
@cbsmontpellier.bsky.social
@neuropresage.bsky.social
@urc-psl.bsky.social
@institutducerveau.bsky.social

Amazing work by Vishnu & the MechanoGut team! 💩⚙️🛠️ Huge thanks to @cbitoulouse.bsky.social imaging & animal facilities, our dear colleagues and collaborators, and funders @cnrs.fr ATIP-Avenir, ED-BSB, @frm-officiel.bsky.social
#Mechanobiology #GutBarrier #EpithelialBiology #CellAdhesion

Rejoignez-nous le 13 novembre 2025 !✨
Inscription sur notre site internet: scienc-e-s-2025.sciencesconf.org

Avec le support de la @sfr-b2s.bsky.social , le pôle égalité du @cbitoulouse.bsky.social , le Toulouse Mind and Brain Institute et @utoulouse.bsky.social

Our work on ribosome hibernation in archaea is out!
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)

5/🧵
This work is the result of a great collaboration between labs at
@ipparis.bsky.social , @ifremer.bsky.social , @cbitoulouse.bsky.social and @pasteur.fr
Many thanks to all colleagues involved 🙌

Claire Rampon et son équipe de Toulouse

🧠 Le projet de Claire Rampon @cbitoulouse.bsky.social explore la mitophagie, (élimination ciblée des mitochondries abîmées).
🔬 Objectif: mieux comprendre la mitophagie et si son dysfonctionnement pourrait contribuer à la maladie d’Alzheimer.
En savoir plus : alzheimer-recherche.org/projets/proj...

Quand l’ARN s’invite dans la réparation de l’ADN Quand notre ADN se casse, nos cellules le réparent avec une haute précision.

Quand l’ARN s’invite dans la réparation de l’ADN ... 🧬

🤝 @lablegube.bsky.social @cbitoulouse.bsky.social

👉 Lire l'article dans @natcellbio.nature.com
buff.ly/CxP2P6N

buff.ly/PY2loYA

A CNRS Junior Professorship on RNA Modifications and Advanced… | Centre for Integrative Biology of Toulouse A CNRS Junior Professorship on RNA Modifications and Advanced Epitranscriptomic Technologies offer at CBI-Toulouse Fixed-term (3–6 years), tenure-track (Chaire de Professeur Junior) Application Dead...

www.linkedin.com/posts/centre...

Kicking off the #MIRA workshop in style with a fantastic keynote from Marie-Cécile Ploy on the global state of #AMR research, insightful and inspiring!

@ipbstoulouse.bsky.social @cbitoulouse.bsky.social

postdoc LMGM | Centre for Integrative Biology of Toulouse Do you want to join the Pneumococcal competence and transformation team ? The team is seeking motivated postdoctoral researchers to apply for Marie Skłodowska-Curie and/or EMBO fellowships, and join ...

www.linkedin.com/feed/update/...

Presentation of Anne Chevallereau

Great talk today @cbitoulouse.bsky.social from @annechevallereau.bsky.social- on the importance of surface receptors in phage adsorption and of intracellular phage defense mechanisms - and the relative importance of each of them in shaping phage host range &productive phage infection 🦠

🐜 How do ants navigate 100+ metres of forest with tiny, low-res eyes, and never get lost?

Antoine Wystrach @cbitoulouse.bsky.social dives into the genius of these insect navigators who mange to find their way without GPS or trails, just memory and vision.

More 👉 bit.ly/42AjG3S

#FrontierResearch

Is our gut epithelium a little cracked ? Turns out—yes🤯 , and especially around goblet cells! Check out the new preprint from our very talented neighbors @cbitoulouse.bsky.social👇

Structural Basis of Lipopolysaccharide Assembly by the Outer Membrane Translocon Holo-Complex Lipopolysaccharide (LPS) assembly at the surfaces-exposed leaflet of the bacterial outer membrane (OM) is mediated by the OM LPS translocon. An essential transmembrane beta-barrel protein, LptD, and a...

Here our new preprint on the LPS holo-translocon doi.org/10.1101/2025... , collaboration with Yves Quentin @JulieMarcoux @fronzeslab.bsky.social @pstansfeld.bsky.social - @cbitoulouse.bsky.social

Venez découvrir les intervenants du @cbitoulouse.bsky.social

Funded post-doc positions in our excellent neighboring lab in the South of France @cbitoulouse.bsky.social @sfbd.bsky.social

🐟 𝗔 𝗻𝗲𝘄 𝗲𝘂𝗿𝗼𝗽𝗲𝗮𝗻 𝗽𝗿𝗼𝗷𝗲𝗰𝘁 𝗹𝗮𝘂𝗻𝗰𝗵𝗲𝗱 𝗮𝘁 𝗖𝗥𝗖𝗔-𝗖𝗕𝗜 𝘁𝗼 𝘀𝘁𝘂𝗱𝘆 𝘇𝗲𝗯𝗿𝗮𝗳𝗶𝘀𝗵𝗲𝘀 𝗺𝗼𝘃𝗲𝗺𝗲𝗻𝘁𝘀 𝗳𝗼𝗿 𝗮𝗻 𝗮𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗼𝗻 𝗱𝗿𝗼𝗻𝗲𝘀 𝗺𝗼𝘁𝗶𝗼𝗻!

Dari Borisov Trendafilov is a new Marie Curie Postdoct co-supervised by Dr Guy Theraulaz, CNRS Research Director and Dr Gautier Hattenberger, prof at ENAC
#Toulouse @cnrs.fr

Pour lancer la @semaineducerveau.bsky.social à #Toulouse : une conférence de M. Lihoreau, chercheur @cnrs.fr au CRCA-CBI, ce soir à 18h30 au Muséum

"A quoi pensent les abeilles ?" pour découvrir les capacités cognitives insoupçonnées de ces insectes au cerveau miniature.

Voici un starter pack pour suivre la recherche en France : instituts, laboratoires, universités et agences.

N'hésitez pas à proposer des comptes à ajouter !
go.bsky.app/JSXcYqn

Merci beaucoup pour cette initiative très utile !

Ribosomal RNA synthesis by RNA polymerase I is regulated by premature termination of transcription The RNA polymerase I (Pol I) enzyme that synthesizes large rRNA precursors, exhibits high rate of pauses during elongation, indicative of a discontinuous process. We show here that Premature Terminati...

Ribosomal RNA synthesis by RNA polymerase I is regulated by premature termination of transcription.
Azouzi et al 2024 @cbitoulouse.bsky.social,
bioRxiv doi.org/10.1101/2023.11.27.568781,
peer reviewed by Review Commons eeb.embo.org/doi/10.1101/2023.11.27.568781.

ALERT! We are approaching our 200th follower on Bluesky !!! We are still far from the number of followers in an old out-of-date social network that we left recently but...
A visit of the CBI #Toulouse will be offered to the 200th follower 😀

This international workshop to be held at CBI on the University of Toulouse scientific campus. Our microbiology unit #LMGM is an active partner of the #MIRA network
@polardlab.bsky.social @genevauxpierre.bsky.social @chgjohnston.bsky.social @raffaeleieva.bsky.social @olayarendueles.bsky.social

More than happy of this very good news! CONGRATS Sarah for the #MSCA fellowship. looking forward to welcoming you at #CRCA-CBI #toulouse
@cnrsbiologie.bsky.social