Vincent Hahaut

ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements - Nature Genetics ChIP-DIP (ChIP done in parallel) is a highly multiplex assay for protein–DNA binding, scalable to hundreds of proteins including modified histones, chromatin regulators and transcription factors, offe...

Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment.
www.nature.com/articles/s41...

27.11.2024 04:13 — 👍 382    🔁 151    💬 9    📌 22

@klausenhauser.bsky.social might be of interest to you 🙂

20.11.2024 09:45 — 👍 0    🔁 0    💬 1    📌 0

Scalable cell-free production of active T7 RNA polymerase The SARS-CoV-2 pandemic highlighted the urgent need for biomanufacturing paradigms that are robust and fast. Here, we demonstrate the rapid process development and scalable cell-free production of T7 ...

Scalable cell-free production of active T7 RNA polymerase
by the Jewett lab
doi.org/10.1101/2024...

20.11.2024 08:00 — 👍 10    🔁 3    💬 1    📌 0

Scientists in Switzerland starter pack, with our avatars

I have created a starter pack of scientists in der Schweiz so we can all hopefully find each other 🇨🇭🧪

go.bsky.app/8rF765Z

19.11.2024 20:45 — 👍 103    🔁 29    💬 26    📌 4