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FrankeLab

@frankelab.bsky.social

Plant Natural Products Group at Leibniz University Hannover. We study the biosynthetic pathways of complex specialised metabolites from plants. https://www.botanik.uni-hannover.de/en/research/research-groups/biochemistry-of-plant-specialised-metabolites

225 Followers  |  128 Following  |  11 Posts  |  Joined: 19.11.2024
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Posts by FrankeLab (@frankelab.bsky.social)

Stellenausschreibungen in Pflanzenwissenschaften und Botanik Stellenausschreibungen in Pflanzenwissenschaften und Botanik

#PlantSciJobs #PlantSciJob

PhD position: Plant Biochemistry

@frankelab.bsky.social @unihannover.bsky.social

Start: 1 July 2026
Deadline: 29 March 2026

www.deutsche-botanische-gesellschaft.de/stellenangeb...

03.03.2026 11:49 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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The Bart Lab at UC Berkeley is looking for a postdoc. Please share!

17.02.2026 00:03 β€” πŸ‘ 37    πŸ” 40    πŸ’¬ 1    πŸ“Œ 0

Congratulations to this great work!

06.02.2026 09:22 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Congratulations, great work! πŸ‘

16.01.2026 10:51 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The hidden danger of Biorender

(& the death of scientific illustration)

A short thread 🧡

01.12.2025 12:51 β€” πŸ‘ 129    πŸ” 43    πŸ’¬ 6    πŸ“Œ 11

Congratz! πŸŽ‰

08.10.2025 09:15 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Post-Docs We are currently recruiting for two post-doc positions in the Lichman lab that require similar skills and experience. We aim to do a joint recruitment process with a single interview. If you apply...

Hello! We are currently hiring for two post-doc positions on projects related to plant natural products, enzymes, and developing new systems to make useful small molecules. More details on our website: lichmanlab.weebly.com/post-docs.html

22.09.2025 07:34 β€” πŸ‘ 7    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
Stellenangebote Stellenausschreibungen in der Botanik und den Pflanzenwissenschaften

#PlantSciJobs #PlantSciJob

Wissenschaftliche Mitarbeit: chemische und molekulare Γ–kologie trophischer Pflanzen-Insekten-Interaktionen.

@unihohenheim.bsky.social in Stuttgart, Germany

Start: 1 MΓ€rz 2026
Deadline: 19 Oktober 2025
www.deutsche-botanische-gesellschaft.de/stellenangeb...

16.09.2025 10:18 β€” πŸ‘ 1    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Naming Challenge: Help Redefine the Glycopeptide Family! We are excited to launch a naming competition inspired by the recent preprint "Phylogenetic distance and structural diversity directing a reclassification of glycopeptide antibiotics" (https://www.bio...

⏰ Just 7 days left for our Glycopeptide Renaming Challenge!
πŸ’‘ Share your best name idea and win 500€

πŸ‘‰ More info and submission here: docs.google.com/forms/d/1ym9...

#secmet #NaturalProducts #Antibiotics #NamingChallenge #Glycopeptides @gdwantibiotics.bsky.social @marghesosio.bsky.social

08.09.2025 12:14 β€” πŸ‘ 10    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0

Ein wirklich toller Artikel, absolut lesenswert! πŸ‘

20.07.2025 12:38 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Nancy Choudhary, Institut fΓΌr ZellulΓ€re und Molekulare Botanik an der UniversitΓ€t Bonn, bei der DurchfΓΌhrung der Genomsequenzierung der Pflanze Withania somnifera. (Bildquelle: Julie Anne V.S. de Oliveira)

Nancy Choudhary, Institut fΓΌr ZellulΓ€re und Molekulare Botanik an der UniversitΓ€t Bonn, bei der DurchfΓΌhrung der Genomsequenzierung der Pflanze Withania somnifera. (Bildquelle: Julie Anne V.S. de Oliveira)

NachschattengewΓ€chse als Basis fΓΌr Arzneimittel: Forschungsteams der #LUH und der @unibonn.bsky.social‬ entschlΓΌsseln Gensequenz zur Bildung von Steroiden. @dfg.de‬ fΓΆrdert das Projekt mit rund 511.00 Euro. http://go.lu-h.de/aNhrb

14.07.2025 14:01 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

And make sure to also check out the excellent work on the withanolide biosynthetic gene cluster by Claude Becker's group
www.pnas.org/doi/10.1073/...
and by Jing-Ke Weng's group:
www.biorxiv.org/content/10.1...

10.07.2025 17:53 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Big thanks also to anonymous Reviewer 1. Their supportive and constructive report led us to discover the role of the dehydrogenase SDR in the biosynthetic pathway. This is how peer review should work. πŸ‘

10.07.2025 17:52 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0
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Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis Nature Communications - Withanolides are plant steroids with potent bioactivities found in many medicinal plants including Withania somnifera, but their biosynthetic pathway is largely unknown....

Extremely happy to see our withanolide biosynthesis paper out in @natcomms.nature.com‬ rdcu.be/evHOF
Fantastic team effort with the Pucker group @bpucker.bsky.social‬ @puckerlab.bsky.social‬ at @unibonn.bsky.social and Heretsch, Herde and Witte groups at @unihannover.bsky.social. Funded by @dfg.de

10.07.2025 17:50 β€” πŸ‘ 26    πŸ” 12    πŸ’¬ 3    πŸ“Œ 3

There is still time to apply πŸ‘‡
#MSCA #Postdoc #Biotech #Bioinformatics #Genomics

07.07.2025 03:59 β€” πŸ‘ 18    πŸ” 15    πŸ’¬ 0    πŸ“Œ 0
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Elucidation and recreation of the biosynthetic pathway for taxol | Plantae Paclitaxel (sold as Taxol) is taxane diterpene natural product of yew trees (Taxus spp.) and a potent stabilizer of microtubules that is effective in treatment of cancers. However…

Plant Science Research Weekly -- Elucidation and recreation of the biosynthetic pathway for taxol (Nature) @cmcclune.bsky.social‬ (Summary by Mary Williams @PlantTeaching.bsky.social)
buff.ly/miccEK3

#PlantaePSRW

02.07.2025 16:15 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1
A cartoon showing a bacterial Xanthomonas cell injecting TALEs into a plant cell to induce expression of target genes.

A cartoon showing a bacterial Xanthomonas cell injecting TALEs into a plant cell to induce expression of target genes.

PhD position open! πŸŒΎπŸ§«πŸ§¬βœ‚οΈπŸ˜ƒ Are you interested in plant pathology and genome editing? Have you ever seen how cool Xanthomonas manipulates the plant cell using TALEs? Don't hesitate to apply! www.uni-hannover.de/en/jobs/id/7...

17.06.2025 11:07 β€” πŸ‘ 13    πŸ” 16    πŸ’¬ 0    πŸ“Œ 1

Dear #molbio buble, can you suggest any (free) software for cloning and sequence analysis? Something similiar to SnapGene (but cheaper) or Benchling (but locally hosted)?
Asking for a newly set up group.

17.06.2025 13:24 β€” πŸ‘ 1    πŸ” 4    πŸ’¬ 2    πŸ“Œ 0
Biochemical breakthrough paves way to reliable supply of anticancer drug | Nature β€˜Missing’ genes needed for the biosynthesis of a natural anticancer drug have been discovered by perturbing and analysing individual cells of yew trees. β€˜Missing’ genes needed for the biosynthesis of a natural anticancer drug have been discovered by perturbing and analysing individual cells of yew trees.

Also check out my News & Views article for more details on the significance of this work πŸ‘‡
rdcu.be/eqwOy

11.06.2025 19:49 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III - Nature An approach that combines single-nucleus RNA sequencing and multiplexed perturbation identifies genes that enable the biosynthesis of direct precursors of the anti-cancer drug Taxol, whose curren...

Fantastic work by the Sattely group on taxol biosynthesis, featuring a highly innovative application of single nuclei sequencing to find elusive biosynthetic genes πŸ‘
www.nature.com/articles/s41...

11.06.2025 19:48 β€” πŸ‘ 20    πŸ” 11    πŸ’¬ 1    πŸ“Œ 1
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Laboratory Technician, Department of Plant and Environmental Sciences

We're hiring!
πŸ₯Ό 2-year lab technician at UCPH from 01 Aug
🌿 Support our research in plant natural products with relevance in agriculture, nutrition, and medicine.
🧬 Your skills: plant molecular biology and/or tissue culture & transformation
πŸ“… Deadline 18 May 2025
jobportal.ku.dk/administrati...

16.04.2025 13:27 β€” πŸ‘ 4    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Expansion of the Stereochemical Space of Triterpenes by Mining Noncanonical Oxidosqualene Cyclases Across the Diversity of Green Plants Triterpenoids and steroids are structurally complex polycyclic natural products with potent biological functions, for example, as hormones. In all eukaryotes, the carbon skeletons of these compounds a...

Started as a very successful master thesis, now published in JACS. Screening sequence similarity networks turned out to be a great way to discover oxidosqualene cyclases with unusual activity from more than thousand plant transcriptome sequence datasets.

pubs.acs.org/doi/10.1021/...

18.03.2025 10:15 β€” πŸ‘ 15    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0

I am trying to find everyone working on plant genomics:
go.bsky.app/NqARJ7V
Please let me know who is already on @bsky.app, but missing in this #PlantGenomics starter pack

28.02.2025 07:39 β€” πŸ‘ 40    πŸ” 34    πŸ’¬ 17    πŸ“Œ 0
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What limits rubisco function? Is it the chemical mechanism? Evolution? In this paper, @prywes.bsky.social et. al explore this question by assaying >99% of single amino acid mutants in Form II rubisco (1/7) doi.org/10.1038/s415...

24.01.2025 20:27 β€” πŸ‘ 74    πŸ” 38    πŸ’¬ 3    πŸ“Œ 4
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A cellulose synthase–like protein governs the biosynthesis of Solanum alkaloids Decades of research on the infamous antinutritional steroidal glycoalkaloids (SGAs) in Solanaceae plants have provided deep insights into their metabolism and roles. However, engineering SGAs in heter...

A cellulose synthase–like protein governs the biosynthesis of Solanum alkaloids | Science www.science.org/doi/10.1126/... @science.org

20.12.2024 02:51 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
The chemical structure of resiniferatoxin, drawn with TWSBI ECO fountain pens in a dark purple and dark gray inks.

The chemical structure of resiniferatoxin, drawn with TWSBI ECO fountain pens in a dark purple and dark gray inks.

Anyone up for some #ToxTuesday?
A lot of us love spicy foods, and the capsaicin in chili peppers that gives us that heat can be addictive. But is there anything hotter? I'm glad you asked. Yes, yes there is. And it's called RESINIFERATOXIN

17.12.2024 16:36 β€” πŸ‘ 84    πŸ” 39    πŸ’¬ 3    πŸ“Œ 3

Awesome job, Omar, congratulations! πŸ‘

13.12.2024 10:14 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

We have a fully funded 4-year PhD studenship available that builds on parts of this pre-print:
biodtp.norwichresearchpark.ac.uk/projects/dis...
πŸ—“οΈ Deadline 25 Nov 2024
Please do get in touch if you're interested!

19.11.2024 12:18 β€” πŸ‘ 2    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0