Czech Academy of Sciences

#research #molecularmachines

Surface-Decoupled Altitudinal and Azimuthal Triptycene-Fused Tetrapodal Molecular Motors
(Bezděková et al., Kaleta) – @angewandtechemie.bsky.social: doi.org/10.1002/anie...

@iocbprague.bsky.social @czechacademy.bsky.social

Tomorrow in Prague: the grand opening of the science art exhibition Circumnavigation in Time!

Experience the passage of time as caught on solarigraphy images by Maciej Zapior, Artem Koval from @czechacademy.bsky.social and colleagues across the globe.

Reservations: rezervace.fzu.cz/exkurze.offe...

🫂 @czechacademy.bsky.social Week brought hundreds of people to @iocbprague.bsky.social—on Saturday alone, over 900 visitors attended the open house for the public.

During the festival, there were also two open houses for schools, including those for English speakers.

#IOCB #IOCBPrague #outreach

Ready for winter! ❄️☃️🪻As winter in the northern hemisphere approaches, plants are preparing to be protected from cold ❄️
Read more on our blog ▶️ 1url.cz/PJ0Vy
#GoBelowground #ExFuMo #rhizome #bud #clonality #overwintering #strategy @ibotcz.bsky.social @czechacademy.bsky.social

Congratulations to our colleague Ondrej Novák, who has once again been ranked among the world’s most highly cited scientists by Clarivate Analytics. He is one of only seven researchers from the Czech Republic to reach the top one percent of most-cited experts this year.
@czechacademy.bsky.social

#research #nanodiamonds

Linker-Free Covalent DNA Functionalization of Quantum-Grade Nanodiamonds (Copak, Steiner, Fialova, Matousek, Plutnar, Chvatil, Gulka, Cígler) – Adv. Opt. Mater.: doi.org/10.1002/adom...

#AdvSciNews @iocbprague.bsky.social @czechacademy.bsky.social

Ready for winter Illustrations, photos, and commentary by F. Curtis Lubbe from the Institute of Botany of the Czech Academy of Sciences. As winter in the northern hemisphere approaches, many plants have already pre…

New on the Belowground blog: Ready for winter plantlifebelowground.wordpress.com/2025/11/12/r...

Our new paper on Enzymatic synthesis of base-modified RNA and influence of the modifications on stability, translation, and CRISPR-Cas9 cleavage - published in ACS Chem. Biol.: doi.org/10.1021/acsc.... @iocbprague.bsky.social @sciencecharles.bsky.social @akademievedcr.bsky.social

The recordings from this year’s Human-aligned AI Summer School (humanaligned.ai/2025/), hosted by @cts.cuni.cz in July 2025, are now available online. All videos are here: www.youtube.com/playlist?lis....

A research team from the Institute of Philosophy of the Czech Academy of Sciences is exploring the ethical use of breakthrough radio holography technology in home palliative care. The Interdisciplinary Research Lab for Bioethics is pioneering this project — the first of its kind in the world.

🌍Excited about our upcoming & final DEA seminar for 2025: Join us on Thu 20.11. at 14:00 online or in Prague for 'Conservation Frontiers: Re-storying wilderness from the margins of Europe' by @georgeiorda.bsky.social (Wageningen Univ.) ⛰️🐻🌳 More info & registration: forms.cloud.microsoft/e/rfKrvjTnE2

#research #bioconjugation #fluorescencelabeling

Thiosulfonate-Derived BODIPY “Stick and Glue” Strategy for Fluorescent Thiol Labeling
(Šálková, Dunlop, Tütüncü, Knejzlík, Slanina) – @angewandtechemie.bsky.social: doi.org/10.1002/anie...

@iocbprague.bsky.social @czechacademy.bsky.social

#research #virology #hepB

UBE2O, a host ubiquitin-conjugating enzyme, is a key regulator of hepatitis B virus maturation and egress
(Lubyová, Tikalová, Janovec, Krulová, Kropáček, Hirsch, Weber) – #jbiolchem: doi.org/10.1016/j.jb...

@iocbprague.bsky.social #biocev @czechacademy.bsky.social

#new_paper: A combined biochemical and computational approach provides evidence for membrane remodelling by the structural scaffold of the endocytic TPLATE complex

DOI: 10.1038/s41477-025-02146-y
@natplants.nature.com
www.nature.com/articles/s41...

#research #immunology

STING agonists trigger monocyte death via apoptosis, pyroptosis, caspase-8 activation and mitochondrial dysfunction
(Polidarová, Šašková, Brázdová): doi.org/10.1038/s414...

@iocbprague.bsky.social @czechacademy.bsky.social @sciencecharles.bsky.social @iphys-cas.bsky.social

Open Science high school internships in English offered at our @fzuavcr.bsky.social, @mbuavcr.bsky.social, @utia.cas.cz, @iocbprague.bsky.social, @ibtcas.bsky.social, @flu-cas.bsky.social, Institute of Atmospheric Physics, & Institute of Inorganic Chemistry.

Register by 30 Nov!

www.otevrenaveda.cz

Otevřená věda | Otevřená věda Projekt Akademie věd ČR otevírá cestu k vědě studentům, pedagogům i veřejnosti. Realizujeme studentské vědecké stáže, Veletrh vědy, výstavy, školíme učitele…

🔬 Open Science #OtevrenaVeda internships for high school students open for registration now till 30 Nov!

🧑‍🎓 High schoolers can apply for year-long research internships at our institutes, which will begin on 2 Jan 2026 and give students a chance to experience science firsthand.

www.otevrenaveda.cz

Pentafluorophenyl-Tagged Poly(2-isopropenyl-2-oxazoline) as a Highly Reactive Precursor for para-Fluoro-Thiol Click Chemistry Poly(2-isopropenyl-2-oxazoline) (PIPOx) is a versatile postpolymerization modification platform, yet its reactions have so far been limited to direct additions of thiols and carboxylic acids with variable efficiency. Here, we show that the reaction of PIPOx with 2,3,4,5,6-pentafluorothiophenol (PFTP) rapidly and cleanly generates poly(N-(2-((perfluorophenyl)thio)ethyl)methacrylamide) (PPFPTEMA), a highly reactive precursor for para-fluoro-thiol (PFT) click chemistry, featuring fast kinetics, equimolarity, orthogonality, and facile product isolation. A wide array of commercially available thiols react quantitatively and selectively with PPFPTEMA, enabling the synthesis of well-defined polymethacrylamides with diverse side-chain functionalities, including ionizable groups, supramolecular motifs, natural compounds, drugs, fluorescent tags, and polymers. The high efficiency and orthogonality of the PFT click reaction also allow multiple thiols to be combined to precisely tailor the copolymer composition. Importantly, when using thiol excess, the pentafluorophenyl groups in PPFPTEMA are found to undergo multiple substitutions under mild conditions, offering an unprecedented level of synthetic flexibility for designing functional polymers. Overall, this work seamlessly integrates PFT click chemistry into the PIPOx platform, establishing a powerful modular framework for the precision synthesis of multifunctional polymers.

#new_paper: Pentafluorophenyl-tagged poly(2-isopropenyl-2-oxazoline) as a highly reactive precursor for para-fluoro-thiol click chemistry
@pubs.acs.org: Pentafluorophenyl, highly reactive precursor
doi.org/10.1021/acs....

🗣️ We are looking forward to hosting Prof. Jana Roithová from #Radboud University for an #invitedlecture "Mass Spectrometry in Research of Chemical Reactions" next week — on Tuesday, 18 November, at 10:00 ► uochb.cz/en/event-calendar/334 ⤵

#UOCHB #IOCB #IOCBPrague #praguelectures #massspec

The effect of hybrid carbon-based nanofillers on the properties of EPDM nanocomposites - Emergent Materials The ethylene-propylene-diene rubber (EPDM)-based hybrid nanocomposites with graphene nanoplatelets (GnPs) and multiwall carbon nanotubes (MWCNTs) were prepared by melt mixing followed by compression m...

#new_paper: The effect of hybrid carbon-based nanofillers on the properties of EPDM nanocomposites
@springernature.com: Nanofillers, nanocomposites
doi.org/10.1007/s422...

Every discovery begins with a question. At the CERGE-EI Festival, during the morning session From Curiosity to Academia, our faculty will share how their curiosity led them to academic careers, and how their research addresses the challenges of today’s world.

🌐 The IOCB Board and management have presented their strategic plans for the next five years.

See more ► www.uochb.cz/en/news/748 ⤵️

#IOCB #IOCBPrague #CzechScience

Comparative gene expression analysis in closely related dermatophytes reveals secondary metabolism as a candidate driver of virulence | Microbiology Spectrum Trichophyton benhamiae var. luteum is an emerging fungal pathogen responsible for a rising number of skin infections transmitted from guinea pigs to humans, especially in Europe. We investigated why t...

The fungal skin pathogen apparently helps itself by producing toxin-like substances that facilitate infection of new hosts.

These substances can suppress the immune response and thus accelerate the spread of the pathogen among humans.

Study ➡️ journals.asm.org/doi/10.1128/... @mbuavcr.bsky.social

Fungi may use toxic substances to spread skin infections from guinea pigs to children - Mikrobiologický ústav AV ČR, v. v. i. A fungus that spreads from domestic guinea pigs causes skin infections in children, especially in Europe. A new study by a team from the Institute of Microbiology of the Czech Academy of Sciences (IMI...

🦠 A fungus that spreads from domestic guinea pigs causes skin infections in children, especially in Europe.

🔬 A new study by a research team from our @mbuavcr.bsky.social reveals why it is so successful.

Details ➡️ mbu.cas.cz/en/aktuality...

We are pleased to welcome Professor Adrian Raftery (University of Washington), who will deliver an
ICS CAS Invited Lecture in Statistical and Environmental Modelling on the topic:

Did the Paris Climate Agreement Work? Evidence from Bayesian Integrated Assessment

🌐 Václav Verner completed the first year of university while still in high school.

He became the first student to start at @vschtpraha.bsky.social directly in the second year.

He is also a three-time gold medalist from the International Chemistry Olympiad. 1/3

Bringing research to life — the Week of the @czechacademy.bsky.social at CERGE_EI

When fire digs deeper: How changing fire frequency reshapes the belowground world of campos rupestres New research by Aline Bertolosi Bombo at the Lab of Vegetation Ecology, São Paulo State University (UNESP). Above are views of the stunning campos rupestres in southeastern Brazil — ancie…

When fire digs deeper 🔥🌹🌱 A new on our blog ▶️ 1url.cz/oJSXO Even in fire-adapted grasslands, too much fire can erode resilience! by @alinebombo.bsky.social
#GoBelowground #ExFuMo #Brazil #CamposRupestres #Resilience #buds #regeneration #rhizome #root
@ibotcz.bsky.social @czechacademy.bsky.social

📚 Ibn Fadlan’s Journey to Russia: A Tenth-Century Traveler from Baghdad to the Volga River, translated from Arabic into Czech by Ondřej Beránek, has received the Turjuman Award, presented by the Sharjah International Book Fair. @academianakladatel.bsky.social

More ➡️ sibf.com/en/awards?aw...

💎 Phys.org featured research led by Petr Cigler from #IOCBPrague, presenting a faster and more affordable way to produce quantum nanodiamonds.

See more ► phys.org/news/2025-10... ⤵

#IOCB #nanodiamonds #research #quantum #materials #science