The Lancet Microbe

Cover of The Lancet Microbe's August issue with a "Coloured Scanning Electron Micrograph of fruiting bodies of the fungus Aspergillus fumigatus".

Our August issue is now online:

www.thelancet.com/journals/lan...

Our journal is #OpenAccess, so you are free to explore all of our content. But these hashtags offer a flavour: #Cdiff #SARS-CoV-2 #microbiome #MVEV #Staphylococcus #decolonisation #tuberculosis #Aspergillus

#IDSky #ClinMicro #OA

July issue is live!🙌

Read contributions of #CVD risk factors in #Japan, #Antimicrobial stewardship interventions in #Vietnam, associations of #STI and #pregnancy outcomes in #Australia & more!

🖋️Editorial: Equitable, safe and reliable #BloodSupply in #WesternPacific
🔗 tinyurl.com/5xb2u7xk

Measles immunity gaps and outbreak risk in a shifting landscape Measles cases are rising globally following first a resurgence in 2019 and then historically low levels during the early years of the COVID-19 pandemic. As of June 2025, 88 853 measles cases have been...

New comment

Measles immunity gaps and outbreak risk in a shifting landscape

www.thelancet.com/journals/lan...

Estimating measles susceptibility and transmission patterns in Italy: an epidemiological assessment Unvaccinated adults contribute substantially to measles transmission in Italy. Heterogeneous immunity gaps exist across regions, with some regions showing persistently low vaccine uptake in children a...

New Research:

Estimating measles susceptibility and transmission patterns in Italy: an epidemiological assessment

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Global typhoid fever incidence: an updated systematic review with meta-analysis Typhoid incidence was high in Africa and Asia, and among young children, thus affirming an ongoing need to prioritise vaccine and non-vaccine prevention of typhoid fever in this age group and for thes...

New Research:

Global typhoid fever incidence: an updated systematic review with meta-analysis

www.thelancet.com/journals/lan...

Characterisation of a persistent SARS-CoV-2 infection lasting more than 750 days in a person living with HIV: a genomic analysis Convergent SARS-CoV-2 evolution, both in and outside the spike protein, observed in this study suggests parallels with the evolutionary process leading to emergence of the omicron VOC. The inferred ab...

And the associated research article:

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@lancetmicrobe.bsky.social

Clinical and public health implications of persistent SARS-CoV-2 infection in a person with HIV disease Despite dramatic advances in HIV care, untreated HIV disease remains a persistent threat to both individual health and the broader public and not merely because untreated HIV infections can lead to ne...

“We are facing a pivotal moment in the care of HIV and other infectious diseases, both locally and globally."

Read our Comment in @lancetmicrobe.bsky.social for our urgent call to action.

Grateful to 🖊️ this with my mentor, @paulsaxmd.bsky.social!
@mgh-id.bsky.social

tinyurl.com/4r45nbb2

Effectiveness of the BNT162b2 and mRNA-1273 JN.1-adapted vaccines against COVID-19-associated hospitalisation and death: a Danish, nationwide, register-based, cohort study Both JN.1-adapted vaccines offered high levels of sustained protection for 4 months against hospitalisation and death. These findings support continued use of regularly updated variant-adapted mRNA va...

New Research:

Effectiveness of the BNT162b2 and mRNA-1273 JN.1-adapted vaccines against COVID-19-associated hospitalisation and death: a Danish, nationwide, register-based, cohort study

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Protection that lasts? MVA-BN against clade IIb mpox Clade IIb monkeypox virus infection was first declared a public health emergency of international concern in 2022. The global outbreak was largely driven by sexual transmission, primarily among men wh...

🆕In their Comment, @emilyevs.bsky.social ‬and @boghuma.bsky.social discuss the new Article published by Ned Latham and Colleagues on fully vaccinated individuals with mpox in NSW, Australia
Read here ➡️ www.thelancet.com/journals/lan...

Clinical features of mpox in fully vaccinated people in New South Wales, Australia: an outbreak investigation and retrospective cohort study A two-dose MVA-BN series continued to protect against extragenital lesions, systemic symptoms, and hospitalisation beyond the point at which antibodies have been found to wane.

🆕An outbreak investigation and retrospective cohort study of fully vaccinated individuals with mpox in NSW, Australia, suggests that protection against severe disease persists beyond the point at which MVA-BN induced antibodies have been found to wane
Read here➡️ www.thelancet.com/journals/lan...

New research article

#SARS-CoV-2 genomic diversity and within-host evolution in individuals with persistent infection in the UK: an observational, longitudinal, population-based surveillance study

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#IDSky #ClinMicro #ViroSky #OpenAccess #OA

🚨Our study on characterising the within-host SARS-CoV-2 evolution during persistent infections is now out in @lancetmicrobe.bsky.social!
👉 www.sciencedirect.com/science/arti...

New research article

Association between mycophenolic acid treatment and infection with specific strains of #Pneumocystis jirovecii in solid organ #transplant recipients in France and Switzerland

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#IDSky #ClinMicro #MycoSky #OpenAccess #OA

"On the one hand, we have a hypothesis underpinned by evidence, although imperfect, and on the other hand we have a hypothesis without evidence, although it might exist."

Our latest editorial in advance of our August issue

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #ViroSky #SARS-CoV-2

There are half a million cases of invasive non-Typhoidal Salmonella (iNTS) every year and while you might know S. Typhimurim and Enteritidis, you may not have heard of S. Panama 💩 🩸 🧫 💊 Check out our latest in @lancetmicrobe.bsky.social doi.org/10.1016/j.la... and the 🧵 below to find out more 1/n

New research article

Global diversity and evolution of #Salmonella enterica serovar #Panama: a genomic epidemiology study

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#IDSky #ClinMicro #MicroSky #AMR #OpenAccess #OA

New review article

Identifying genomic surveillance gaps in Africa for the global public health response to #WestNileVirus: a systematic review

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#IDSky #ClinMicro #ViroSky #OpenAccess #OA

Clinical and public health implications of persistent SARS-CoV-2 infection in a person with HIV disease Despite dramatic advances in HIV care, untreated HIV disease remains a persistent threat to both individual health and the broader public and not merely because untreated HIV infections can lead to ne...

▶️Clinical and public health implications of persistent SARS-CoV-2 infection in a person with HIV disease

@thefrancesue.bsky.social @paulsaxmd.bsky.social

Via @lancetmicrobe.bsky.social

www.thelancet.com/journals/lan...

Our first issue is out now! 🎉
#openaccess

Explore and download at: hubs.li/Q03yqVNW0

Read our inaugural Editorial, a varied selection of comments and research articles, and more.

Thank you to our authors and reviewers
#medsky #familymedicinesky #primaryhealthcare #primarycare #communitycare

Pathogen Epidemiology Review Group The Pathogen Epidemiology Review Group (PERG) under the leadership of Dr Anne Cori, are undertaking an ambitious project to make key epidemiological...

Find out more about the Pathogen Epidemiology Review Group (PERG) 👇
www.imperial.ac.uk/mrc-global-i...
@imperialcollegeldn.bsky.social @imperialsph.bsky.social @lancetmicrobe.bsky.social @eonore.bsky.social @thomrawson.bsky.social @anne-cori.bsky.social
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Severe acute respiratory syndrome (SARS) mathematical models and disease parameters: a systematic review SARS-CoV-1 was the first documented coronavirus to cause an acute epidemic in humans and remains a priority pathogen owing to the risk of re-emergence. Robust estimates of key epidemiological paramete...

This is the first respiratory virus reviewed by the Pathogen Epidemiology Review Group as part of the series & now available in @lancetmicrobe.bsky.social entitled severe acute respiratory syndrome (SARS) mathematical models and disease parameters 👉
www.thelancet.com/journals/lan...
🧵2/3

YouTube video by MRC Centre for Global Infectious Disease Analysis Ep 127. Science in Context - SARS with Dr Thomas Rawson & Christian Morgenstern (24-07-2025)

NEW EPISODE! @eonore.bsky.social is joined by @thomrawson.bsky.social & Christian Morgenstern to talk about #SARS, differences between SARS-CoV-1 & SARS-CoV-2 (virus causing COVID19), their systematic review of models, outbreaks & parameters to inform future responses👇
youtu.be/dloAOywYrDE
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New review article

Severe acute respiratory syndrome ( #SARS) mathematical models and disease parameters: a systematic review

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #ViroSky #SARS-CoV #SARS-CoV-1 #OpenAccess #OA

Plus linked comment

Clinical and public health implications of persistent #SARS-CoV-2 infection in a person with #HIV disease

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #ViroSky #COVID-19 #OpenAccess #OA

New research article

Characterisation of a persistent #SARS-CoV-2 infection lasting more than 750 days in a person living with #HIV: a genomic analysis

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #ViroSky #COVID-19 #OpenAccess #OA

Global emergence and transmission dynamics of carbapenemase-producing Citrobacter freundii sequence type 22 high-risk international clone: a retrospective, genomic, epidemiological study Our study provides evidence to suggest that Citrobacter species are emerging carriers of carbapenem-resistance genes. These findings provide insight into the population structure of CPC species and hi...

Citrobacter freundii ain't ever been a friend of ours... now becoming even more hostile!
#IDSky #ClinMicro #AMR #MedSky
@lancetmicrobe.bsky.social

www.thelancet.com/journals/lan...

Blood RNA biomarkers and C-reactive protein for triage of adult patients with tuberculosis lymphadenitis and pericarditis in South Africa: a single-centre, prospective, observational, diagnostic accur... Our results suggest RNA biomarkers show better accuracy and clinical utility than C-reactive protein to trigger confirmatory tuberculosis testing in patients with tuberculosis lymphadenitis and tuberc...

Important #TBSky paper @lancetmicrobe.bsky.social by @mnoursad.bsky.social & @innate2adaptive.bsky.social

Diagnosing TB in lymph nodes or pericarditis a challenge

RNA biomarkers better than CRP to trigger confirmatory testing, but still not as good as what WHO specifies for TB triage tests #IDSky

Pathways to an Intergovernmental Panel on Pandemics: lessons from the IPCC and IPBES Colin J Carlson, Christopher H Trisos, Ben Oppenheim, Shweta Bansal, Sara E Davies, Aïda Diongue-Niang, Victoria Y Fan, John D Kraemer, Rachel Golden Kroner, Lawrence O Gostin, David T S Hayman, Marion Koopmans, Torre E Lavelle, Carlos G das Neves, Zoe O’Donoghue, Laura M Pereira, Benjamin Roche, Matiangai Sirleaf, Kayla Zamanian, Carlos Zambrana-Torrelio, Alexandra L Phelan Pandemics pose a global threat to human wellbeing, justice, economies, and ecosystems and are comparable with other planetary crises such as climate change and biodiversity loss in terms of urgency and impact. The global community would benefit from a dedicated scientific synthesis body to assess pandemic risks and solutions. In this Personal View, we explore proposals for an Intergovernmental Panel on Pandemics and assess potential pathways to its creation. Learning lessons from the Intergovernmental Panel on Climate Change (IPCC) and the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) might help national governments and international organisations to chart a course through important decisions about format, governance, operations, scientific scope and process, and ability to recommend policies that make the world safer.

🚨 Very, very big news. Today, a global coalition - including members of the IPCC, IPBES, and WHO expert advisors, as well as independent virologists, epidemiologists, and lawyers - started the process of creating an "IPCC for Pandemics."

🔓 www.thelancet.com/journals/lan...
🧵 Five things to know 👉

The impact of sulfadoxine–pyrimethamine resistance on the effectiveness of intermittent preventive treatment for the prevention of malaria in pregnancy in Africa: an updated systematic review and meta... IPTp-SP antimalarial efficacy is greatly reduced in very high resistance areas. However, it remains effective at reducing low birthweight in these areas, possibly through non-malaria effects on fetal ...

New Research:

The impact of sulfadoxine–pyrimethamine resistance on the effectiveness of intermittent preventive treatment for the prevention of malaria in pregnancy in Africa: an updated systematic review and meta-analysis

www.thelancet.com/journals/lan...

Refining COVID-19 care for immunocompromised patients Since 2022, with the emergence of highly transmissible omicron variants and the relaxation of social distancing measures, protecting individuals who are immunocompromised from SARS-CoV-2 exposure has ...

New Comment:

Refining COVID-19 care for immunocompromised patients

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