The Lancet Microbe

New research article

Predicting bloodstream infection by plasma cell-free metagenomic sequencing: a prospective cohort study

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #OpenAccess #OA

Alt: Cover art for The Lancet Pulse, a new podcast from The Lancet Group. A blue square is overlaid by circles of increasing size, like ripples on a lake.

Introducing a new Lancet podcast 🎙️

Every month, The Lancet Pulse explores the latest advances and toughest challenges in clinical medicine.

Listen to episodes 0 through 3 today: spkl.io/63320AQeDi

Read our March issue!

Featuring RSV vaccination in elderly people, itraconazole for pulmonary aspergillosis and the global burden of Chagas disease.

bit.ly/3N5mqBx

📰 Comment: Three reasons why the European region should worry about #tuberculosis

"Ongoing deaths, conflicts, and forced migration must motivate us to act and do more to end tuberculosis worldwide"

🔓 Read in full here: www.thelancet.com/journals/lan...

@madhupai.bsky.social @who.int

New research article

Characterisation of #Bordetella #pertussis virulence and macrolide resistance in Australia by targeted culture-independent sequencing: a genomic epidemiology study

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #AMR #OpenAccess #OA

New personal view article

Spillover of #pseudorabies virus variants to humans: an urgent call for pseudorabies eradication in domestic pigs

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#IDSky #ClinMicro #ViroSky #zoonosis #OpenAccess #OA

📢NEW: February issue now online featuring #Sepsis, #ColonCancer, #HIV, #PalliativeCare, #Autism, #TB, #HeartFailure, and much more with our editorial on social media bans for young people

…all available #OpenAccess❗️

Read more here: www.thelancet.com/issue/S2589-...

Attribution: Getty

New review article

Global perspective on gaps in fungal diagnostics in low-resource settings: WHO landscape analysis and research priorities for invasive fungal diseases

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#IDSky #ClinMicro #MycoSky #OpenAccess #OA

New research article

Serotype-specific pneumococcal invasiveness: a global meta-analysis of paired estimates of disease incidence and carriage prevalence

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#IDSky #ClinMicro #Streptococcus #IPD #OpenAccess #OA

Figure showing diagnostic and therapeutic algorithm of leprosy. Copyright: 2025 Elsevier Ltd. All rights are reserved.

Leprosy, or Hansen's disease, remains a key global health issue.

In a Seminar, authors provide an update on key public health and clinical aspects of the disease: spkl.io/63328AQzar

New research article

Efficacy and safety of #lenacapavir, #teropavimab, and #zinlirvimab: week-26 primary outcome results from a multicentre, open-label, randomised, active-controlled, phase 2 study

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #ViroSky #HIV #OpenAccess #OA

New research article

Spatiotemporal patterns of #RiftValleyFever virus in Africa: a retrospective genomic epidemiology and phylodynamic modelling study

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #ViroSky #RVFV #OpenAccess #OA

New research article

#Bedaquiline resistance in patients with Xpert MTB/RIF Ultra-tested #rifampicin resistant #tuberculosis in the Western Cape, South Africa: a prospective study

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #TBSky #TB #AMR #OpenAccess #OA

New research article

#Bedaquiline resistance in patients with Xpert MTB/RIF Ultra-tested #rifampicin resistant #tuberculosis in the Western Cape, South Africa: a prospective study

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #TBSky #TB #AMR #OpenAccess #OA

Development and validation of the AURIS score for predicting candidaemia in Candidozyma auris-colonised patients in the intensive care unit: a bicentric retrospective cohort study The AURIS score provides a pragmatic tool for risk stratification among C auris-colonised ICU patients, with value in identifying those at low risk of candidaemia, reducing unnecessary empirical antif...

New Research

Development and validation of the AURIS score for predicting candidaemia in Candidozyma auris-colonised patients in the intensive care unit: a bicentric retrospective cohort study

www.thelancet.com/journals/lan...

New research article

Spatiotemporal patterns of #RiftValleyFever virus in Africa: a retrospective genomic epidemiology and phylodynamic modelling study

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #ViroSky #RVFV #OpenAccess #OA

The Lancet Global Health editors on conferences, implementation, and 2026 Podcast Episode · The Lancet Global Health in conversation with · 02/16/2026 · 29m

🎙️ Our podcast this month features your TLGH editorial team! Zoë, Pingyue, Gavin, and Shangrong discuss the problems with conferences in HICs, equitable research partnership, and the research we'd like to see in 2026!
Apple: podcasts.apple.com/us/podcast/t...
Spotify: open.spotify.com/episode/2y7y...

New research article

Efficacy and safety of #lenacapavir, #teropavimab, and #zinlirvimab: week-26 primary outcome results from a multicentre, open-label, randomised, active-controlled, phase 2 study

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #ViroSky #HIV #OpenAccess #OA

Efficacy of ETVAX, a vaccine against enterotoxigenic Escherichia coli-positive diarrhoea in Gambian children: a double-blind, randomised, placebo-controlled, phase 2b trial ETVAX was safe and immunogenic. Although the primary endpoint was not met, the secondary and exploratory findings suggest ETVAX protects Gambian children against ETEC-positive MSD particularly when ad...

New Research

Efficacy of ETVAX, a vaccine against enterotoxigenic Escherichia coli-positive diarrhoea in Gambian children: a double-blind, randomised, placebo-controlled, phase 2b trial

www.thelancet.com/journals/lan...

Prophylactic antibiotics to prevent recurrent urinary tract infections and risk of antibiotic resistance: target trial emulation with the SAIL Databank In our target trial emulation, prophylactic antibiotic use did not increase the risk of hospital admission with an antibiotic-resistant infection or urine infection, but it did increase the risk of ur...

NEW ONLINE. A target trial emulation has looked at the use of prophylactic antibiotics in women with recurrent urinary tract infections. The findings showed a potentially higher risk of antibiotic resistance, but no increase in risk of hospital admission.
👉 www.thelancet.com/journals/lan...

I worked at WHO: the USA leaving will not make America healthier On Jan 30, 2020, WHO declared COVID-19 a Public Health Emergency of International Concern (PHEIC), the highest alarm it can sound, which is used for moments when the world must act together or risk ca...

New comment

I worked at WHO: the USA leaving will not make America healthier

www.thelancet.com/journals/lan...

The looming crisis of bedaquiline-resistant tuberculosis and a promising way forward Drug-resistant tuberculosis is entering a new and dangerous phase. Bedaquiline and other newer drugs have transformed drug-resistant tuberculosis treatment, yet resistance to these agents is now being...

New Personal View

The looming crisis of bedaquiline-resistant tuberculosis and a promising way forward

www.thelancet.com/journals/lan...

Global health leap: an urgent call to action The ongoing global health crisis presents a pivotal opportunity to transform and reform the fragmented global health architecture. This Viewpoint issues an urgent call for coordinated action—a Global ...

"We need to address this crisis head-on to avoid a generational legacy of increased morbidity, mortality, and insecurity."

@sanianishtar.bsky.social calls for coordinated action—a Global Health Leap— to transform & reform the fragmented global health architecture: tinyurl.com/mvzw872t

Figure showing tetanus pathophysiology. Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

Tetanus, although preventable by a highly effective vaccine, continues to cause 30,000-50,000 deaths annually.

A recent Seminar explores the current state of tetanus, underscoring the importance of sustained immunisation efforts & improved access to care: spkl.io/63321AtXJW

The February 2026 issue of The Lancet Regional Health - Americas is now available online!
lnkd.in/ga54tTSX

In this issue: #E-cigarette, #GastrointestinalSurgery, #ChildGrowth, #Chagas, #BariatricSurgery, #Dementia, #PediatricARDS, #HealthSystemResilience, #NasopharyngealCarcinoma, and much more.

New research article

The effect of pneumococcal conjugate vaccine and pneumococcal polysaccharide vaccine on nasopharyngeal colonisation following human infection challenge with serotype 3 and serotype 6B (PREVENTING PNEUMO 2)

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #OpenAccess #OA

February cover of The Lancet Microbe

Our February issue is now online:

www.thelancet.com/journals/lan...

Our journal is #OpenAccess, so you are free to explore all of our content. But these hashtags offer a flavour: #Klebsiella #AMR #malaria #dermatophytosis #trichuriasis #gonorrhoea #meningitis #tuberculosis

#IDSky #ClinMicro #OA

Our March issue is now live at www.thelancet.com/gastrohep!

Content includes: #alcohol, #IBD, #HBV, #MASLD, #SIMD (#SIBO) + more!

#GastroSky #LiverSky #MedSky

Reimagining radical cure for Plasmodium vivax Eliminating Plasmodium vivax malaria remains one of the most persistent challenges in global health. Relapses from dormant liver-stage hypnozoites continue to be the major biological barrier to contro...

New comment

Reimagining radical cure for Plasmodium vivax

www.thelancet.com/journals/lan...

Effectiveness and safety of 7-day high-dose primaquine and single-dose tafenoquine versus 14-day low-dose primaquine in patients with Plasmodium vivax malaria (EFFORT): a multicentre, open-label, rand... Both unsupervised 7-day high-dose primaquine and single-dose tafenoquine were well tolerated in patients with normal G6PD activity and they had a lower risk of P vivax recurrence compared with those i...

New Research

Effectiveness and safety of 7-day high-dose primaquine and single-dose tafenoquine versus 14-day low-dose primaquine in patients with Plasmodium vivax malaria (EFFORT): a multicentre, open-label, randomised, controlled, superiority trial

www.thelancet.com/journals/lan...